Texas Medical Center Vacations

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Where to stay in Texas Medical Center

Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Discovery Green which includes a city, central business district and a high rise building

Downtown Houston

3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

Find hotels in Downtown Houston

Texas Medical Center Hotel Deals

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
The price is AED 327 per night from Jan 4 to Jan 5
AED 327
AED 387 total
4 Jan - 5 Jan
includes taxes & fees
8.2/10 Very Good! (1,791 reviews)
The hotel was great and convenient. Easy check in an check out. Will definitely stay again.

Reviewed on 22 December 2025

Hilton Houston Plaza/Medical Center
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
The price is AED 479 per night from Jan 18 to Jan 19
AED 479
AED 560 total
18 Jan - 19 Jan
includes taxes & fees
9/10 Wonderful! (3,642 reviews)
The hotel was wonderful. Excellent rooms and the lobby is stunning. Amazing staff; whether it’s the front desk or the valet crew, everyone was so friendly and helpful. Highly recommend this hotel.

Reviewed on 2 January 2026

Blossom Hotel Houston, Curio Collection by Hilton
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
The price is AED 503 per night from Jan 3 to Jan 4
AED 503
AED 626 total
3 Jan - 4 Jan
includes taxes & fees
9/10 Wonderful! (1,031 reviews)
Everything was great. No complaints here. Very convenient location and can access from the Hospital Bridges.

Reviewed on 26 December 2025

The Westin Houston Medical Center/Museum District
See all 6,819 properties in Texas Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Texas Medical Center

Close to the entrance of convention center.

George R. Brown Convention Center

4/5(961 reviews)

During your trip, find out what's happening at George R. Brown Convention Center, a top convention center in Houston. Experience the great live music and lively festivals in this vibrant area.

George R. Brown Convention Center
NASA Johnson Space Center

NASA Johnson Space Center

4.5/5(1,214 reviews)

After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.

NASA Johnson Space Center
At the main entrance.

Toyota Center

4/5(967 reviews)

Catch an event at Toyota Center during your trip to Houston. Experience the acclaimed theater scene and entertainment choices in this vibrant area.

Toyota Center