The Best Resorts & Hotels with Spas in Tlaquepaque from AED 173 in 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Tlaquepaque hotels with a spa

A bathroom with a tiled wall, a sink with a mirror, and a bench.

1. Quinta Don Jose Boutique Hotel

Centro

Escape to this boutique inn with rejuvenating spa services, a tranquil garden waterfall pool, and unique individually furnished rooms.

AED 520 total

includes taxes & fees

5 Nov - 6 Nov

A bride seated at a wooden table with potted plants and candles in the background.

2. Casa Morales Hotel Boutique Tlaquepaque

Centro

Indulge in rejuvenating spa services at this beautiful boutique guesthouse with peaceful gardens and jetted tubs.

AED 585 total

includes taxes & fees

5 Nov - 6 Nov

3. Aura Hotel Boutique

Centro

Discover a boutique escape where massage therapy meets modern comfort in Guadalajara's cultural heart, steps from the cathedral.

AED 296 total

includes taxes & fees

6 Nov - 7 Nov

A corridor with arches, potted plants, wooden furniture, and a tiled floor.

4. Casona Tlaquepaque Temazcal y Spa

Centro

Revitalizing escape at a colonial spa haven with aromatherapy, mud baths, and garden oasis.

AED 281 total

includes taxes & fees

5 Nov - 6 Nov

A poolside area with a tiled pool, lounge chairs, and a table with a glass of wine.

5. Sara N Hotel & Spa

Zapotlanejo

Escape to this central city hotel with a full-service spa, outdoor pool, and sauna for complete wellness restoration.

AED 309 total

includes taxes & fees

5 Nov - 6 Nov

A cozy room with a bed, a stone wall, and a window with curtains.

6. Hotel Santo Santiago

Tonala Centro

Fragrant aromatherapy and hot stone massages await in this serene spa hotel.

AED 210 total

includes taxes & fees

5 Nov - 6 Nov

A person lying on a bed under a transparent dome-like structure, possibly for a spa treatment.

7. Hard Rock Hotel Guadalajara

Zapopan

Immerse in signature spa treatments and rooftop pool relaxation at this hotel steps from Guadalajara's attractions.

AED 597 total

includes taxes & fees

9 Nov - 10 Nov

A room with a massage table, a bed, and a small stool.

8. Hotel Morales Historical & Colonial Downtown Core

Downtown Guadalajara

Escape to a historic boutique hotel with rejuvenating spa services and a serene rooftop terrace in the heart of downtown Guadalajara.

AED 270 total

includes taxes & fees

4 Dec - 5 Dec

A spa room with two massage tables, a statue, and a large window with sheer curtains.

9. Hotel Hacienda San Isidro

Tala

Rejuvenate at this mountain hotel where couples can enjoy massages together at the full-service spa surrounded by natural serenity.

AED 508 total

includes taxes & fees

5 Nov - 6 Nov

A modern lounge area with wooden chairs, round tables, and a sofa.

10. Grand Fiesta Americana Guadalajara Country Club

Providencia

Spa sanctuary offers tranquil rejuvenation with massages, facials, and a steam room in upscale Guadalajara.

AED 943 total

includes taxes & fees

4 Dec - 5 Dec

View all properties

Choose what matters most at spa hotels in Tlaquepaque

Pool

Breakfast included

Top Tlaquepaque Hotel Reviews

Casa Morales Hotel Boutique Tlaquepaque

Centro

10/10 Excellent

Stunningly beautiful hotel with top notch art collection to enjoy on premises. Owner Ester and her husband Larry are the perfect hosts. Both are bilingual. Staff are efficient. Pepe provided support and security, Myrna was a great cook for the breakfast that was included. Hotel was always kept clean. Bed was very comfortable. Located 1 block from Tlaquepaque's restaurant and night life. I will definitely stay at Casa Morales again!

Leonor

Quinta Don Jose Boutique Hotel

Centro

10/10 Excellent

Raul

A hotel room with two beds, wooden paneling on the walls, and framed artwork on the wall.

Origen 438 Luxury Boutique Hotel

Downtown Guadalajara

10/10 Excellent

The hotel is definitely a hidden gem! The rooms are a great size and by far the nicest I've stayed at in Guadalajara. We were upgraded to King suite and it did not disappoint. The Hotel was literally a 1 minute walk to Downtown and the area was most definitely safe. The staff was the best part!! From the check-in staff, security, servers and to our amazing bartender Abraham!!! We will definitely be back.

Marlena

Grand Fiesta Americana Guadalajara Country Club

Providencia

10/10 Excellent

Teresa

Hotel Morales Historical & Colonial Downtown Core

Downtown Guadalajara

10/10 Excellent

Ann

A courtyard with outdoor seating, a decorative lantern, and a view of the building's interior.

Palpatio Hotel Boutique

Downtown Guadalajara

10/10 Excellent

Julio

A swimming pool with a tiled floor, a covered seating area with cushions, and a patterned wall.

GALA Hotel Boutique

Colonia Americana

10/10 Excellent

Gabriel

Hard Rock Hotel Guadalajara

Zapopan

10/10 Excellent

Anonymous traveler

Sara N Hotel & Spa

Zapotlanejo

10/10 Excellent

Claribel

A poolside area with a lounge chair, a table, and a view of the pool.

Hotel Estancia Business Class

Zona Expo

10/10 Excellent

Since we walked into the lobby we were greated by the bell boy, and the person at the front desk in a very nice and warm way, checked in with no issues and was informed of the restaurant service, as well room service. The room was clean and fresh very well kept, you can tell the cleaning crew takes a lot of pride in what they do. Every employee that we encounter thru out the whole stay was nice, kind and very helpful. The pool area was clean and the water in tho pool sparkly, it closes at 9 pm...

David

Aura Hotel Boutique

Centro

10/10 Excellent

I was arriving very lat actually very early in the morning and the arranged my taxi from the airport they gave me all of the codes I needed to get into my room so that at 4 in the morning from the time I got out of the taxi it was less than 2 minutes that I was in the room. Breakfast was exceptional, the orange juice was freshly squezed and the food was great. The location was exactly where it was described and the room was net well laid out and very comfortable There is no question that If I...

Allen

A modern bedroom with a large window, a bed, and a shower area.

Casa Habita, Guadalajara, a Member of Design Hotels

Zona Minerva

10/10 Excellent

Jorge M.

Frequently Asked Questions

Looking for a spa hotel in Tlaquepaque?

Soothe the senses with some time in one of our wonderful spa hotels. Travelers recommend the gourmet restaurants in Tlaquepaque. Take in the culture at the art galleries and museums during your stay. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your weekend away.

What is the best spa hotel in Tlaquepaque?

Casa Morales Hotel Boutique Tlaquepaque is a top spa hotel with 7 rooms, an outdoor entertainment area, and concierge services. Spend an afternoon at the spa where you’ll find facials, Swedish massages, and deep-tissue massages. In-room massages are also available. Other popular spa hotels in Tlaquepaque include Casona Tlaquepaque Temazcal y Spa and Posada Margaritas.

How many spa hotels will I find in Tlaquepaque?

Among Expedia's 89 accommodation options in Tlaquepaque, there are 3 spa hotels.

What's there to see and do in Tlaquepaque?

Enjoy Tlaquepaque with a stop at San Pedro Parish, Refuge Cultural Center, and Capilla del Calvario. If you have some spare time during your trip, you might want to check out Jardin Rincon de los Poetas and Tlaquepaque Letters.

What is a Tlaquepaque spa hotel?

Spa hotels in Tlaquepaque provide lodging and have a full on-site spa offering services like couples massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

Find Resorts & Hotels with Spas in Tlaquepaque

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Tlaquepaque hotels with a spa

1. Quinta Don Jose Boutique Hotel

2. Casa Morales Hotel Boutique Tlaquepaque

3. Aura Hotel Boutique

4. Casona Tlaquepaque Temazcal y Spa

5. Sara N Hotel & Spa

6. Hotel Santo Santiago

7. Hard Rock Hotel Guadalajara

8. Hotel Morales Historical & Colonial Downtown Core

9. Hotel Hacienda San Isidro

10. Grand Fiesta Americana Guadalajara Country Club

Choose what matters most at spa hotels in Tlaquepaque

Top Tlaquepaque Hotel Reviews

Casa Morales Hotel Boutique Tlaquepaque

10/10 Excellent

Frequently Asked Questions

Looking for a spa hotel in Tlaquepaque?

What is the best spa hotel in Tlaquepaque?

How many spa hotels will I find in Tlaquepaque?

What's there to see and do in Tlaquepaque?

What is a Tlaquepaque spa hotel?