A historic building with ornate architecture and a modern brick structure in the foreground.

Find Resorts & Hotels with Spas in Uptown, OH

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Check availability on Uptown Resorts & Hotels with Spas

Tonight
16 Oct - 17 Oct
Tomorrow
17 Oct - 18 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Uptown hotels with a spa

A modern hotel room with a bathroom, a sofa, and a bed.
A hotel room with a wooden headboard, a bedside lamp, a laptop, and a framed picture on the wall.
A dining area with wooden tables and chairs, a wine cellar with wine racks, and a seating area with cushioned sofas.
A spiral staircase with a black metal railing and a white wall.

1. 21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati
Downtown Cincinnati
  • Luxuriate in rejuvenating spa treatments and facials at this boutique hotel with 3 dedicated wellness rooms.
AED 559
AED 685 total
includes taxes & fees
5 Nov - 6 Nov
21c Museum Hotel Cincinnati
A reception area with a reception desk, two armchairs, and a round table.
Restaurant
A modern bar area with a circular seating arrangement, a central bar counter, and a decorative light fixture.
A large brick building with a prominent entrance and a sign reading "The Lyole Hotel."

2. The Lytle Park Hotel, Autograph Collection

The Lytle Park Hotel, Autograph Collection
Downtown Cincinnati
AED 1,282
AED 1,529 total
includes taxes & fees
18 Oct - 19 Oct
The Lytle Park Hotel, Autograph Collection
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Choose what matters most at spa hotels in Uptown

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Uptown Hotel Reviews

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