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Find Luxury Hotels in Wytheville, VA

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Check availability on Wytheville Luxury Hotels

Tonight
5 Dec - 6 Dec
Tomorrow
6 Dec - 7 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top Wytheville Luxury Hotels

Bar (on property)
Ramada by Wyndham Wytheville

Ramada by Wyndham Wytheville

2.5 star property
Wytheville
8.0 out of 10, Very Good, (1496)
"Clean room - comfortable beds - friendly staff "
United States
ELIZABETH
The price is AED 217
AED 254 total
includes taxes & fees
7 Dec - 8 Dec
Ramada by Wyndham Wytheville
Exterior
Travel Lite Motel

Travel Lite Motel

2.0 star property
Wytheville
7.4 out of 10, Good, (180)
"Was nice to be in the little town of Wytheville and be able to walk to dinner"
United States
LAUREL
Travel Lite Motel
Lobby
Quality Inn & Suites

Quality Inn & Suites

2.0 star property
Wytheville
7.4 out of 10, Good, (70)
"A variety for breakfast and plenty of parking."
United States
Diane
The price is AED 234
AED 270 total
includes taxes & fees
5 Jan - 6 January 2026
Quality Inn & Suites
Lobby
Red Roof Inn Wytheville

Red Roof Inn Wytheville

3.0 star property
Wytheville
8.4 out of 10, Very Good, (156)
"Room was clean and parking in front of room was convenient."
United States
Kathleen
The price is AED 225
AED 259 total
includes taxes & fees
11 Dec - 12 Dec
Red Roof Inn Wytheville
Lobby
Edyn Hotel By Townhouse Wytheville US 52

Edyn Hotel By Townhouse Wytheville US 52

2.0 star property
Wytheville
6.8 out of 10, (303)
"Nice clean room exactly as pictured. Nice pool, sauna and hot tub. Wonderful host. Would stay here again. "
United States
Dewayne
The price is AED 213
AED 271 total
includes taxes & fees
6 Dec - 7 Dec
Edyn Hotel By Townhouse Wytheville US 52
Exterior
Days Inn by Wyndham Wytheville

Days Inn by Wyndham Wytheville

2.0 star property
Wytheville
8.0 out of 10, Very Good, (1000)
"Room was clean and staff was friendly."
United States
Diahanna
The price is AED 203
AED 234 total
includes taxes & fees
28 Dec - 29 Dec
Days Inn by Wyndham Wytheville
Room, 2 Queen Beds, Non Smoking | Desk, iron/ironing board, free WiFi
Americas Best Value Inn Wytheville

Americas Best Value Inn Wytheville

2.5 star property
Wytheville
7.2 out of 10, Good, (484)
"Check in staff very friendly and helpful."
Canada
Christina
Americas Best Value Inn Wytheville
Front of property - evening/night
The Bolling Wilson Hotel

The Bolling Wilson Hotel

3.0 star property
Wytheville
9.6 out of 10, Exceptional, (773)
"Great place. Great staff"
United States
Kevin
The price is AED 447
AED 554 total
includes taxes & fees
7 Dec - 8 Dec
The Bolling Wilson Hotel
Lobby
Deluxe Inn Wytheville

Deluxe Inn Wytheville

2.5 star property
Wytheville
7.6 out of 10, Good, (1000)
" The pool was closed, it was the off season. Clean and quiet, the bed was comfortable. Breakfast was very small. There was some cereal and milk, juice, bananas and coffee and tea. "
United States
Kimberly J
The price is AED 234
AED 270 total
includes taxes & fees
4 Jan - 5 January 2026
Deluxe Inn Wytheville
Free daily buffet breakfast
Comfort Suites Wytheville

Comfort Suites Wytheville

2.5 star property
Wytheville
8.8 out of 10, Excellent, (1001)
"The staff was very friendly and tgecroom was spotless. "
United States
Kim
The price is AED 340
AED 392 total
includes taxes & fees
4 Jan - 5 January 2026
Comfort Suites Wytheville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Wytheville Hotel Reviews

Red Roof Inn Wytheville

Red Roof Inn Wytheville

10/10 Excellent
"We stayed 1 night on Dec 2, 2025. 2 adults and a German Shepard. The motel appears to be recently remodeled and everything was bright and sparkling clean. For a motel I rate it 5 stars."
Russell 1-night trip
Posted 3 days ago
Red Roof Inn Wytheville

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Frequently asked questions

Are you looking for a luxury hotel for your Wytheville vacation?
Amenities are important when you plan a trip, so we make it easy to get what you'd like to make your stay special. If you want an upscale hotel with fine dining, a spa, or several swimming pools, Expedia can help you find the best luxury hotel experience that Wytheville offers. During your visit, you might want to enjoy the entertainment which Wytheville is known for.
When can I expect good weather in Wytheville?
Planning for the weather is a good way to make your trip to Wytheville relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 68°F, while the coldest months are January and February with an average of 36°F. Average annual precipitation for Wytheville is 44 inches.
What's there to see and do in Wytheville?
When you're in Wytheville, enjoy exploring the sights and attractions here including Wytheville Meeting Center, Wohlfahrt Haus Dinner Theatre, and Galewinds Amusement Park. If you have a little extra time during your trip, you might want to check out Big Walker Lookout and Jefferson National Forest.