A large suspension bridge, industrial cranes, and a calm river.

Find 5 Star Hotels in Panama Canal Zone from AED 425

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Check availability on Panama Canal Zone 5 Star Hotels

Tonight
3 Oct - 4 Oct
Tomorrow
4 Oct - 5 Oct
Next weekend
9 Oct - 11 Oct
In two weeks
16 Oct - 18 Oct

Our top choices for Panama Canal Zone 5-star hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A modern hotel room with a dining area, a TV, and a city view.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
United States
Avanel
AED 506
AED 556 total
includes taxes & fees
25 Oct - 26 Oct
Hotel Riu Plaza Panama
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.
A tall, modern building with a prominent logo at the top, surrounded by other high-rise buildings in a cityscape.
A modern interior with a decorative ceiling, a person in a white dress, and a blue-lit wall.
An outdoor seating area with wicker chairs and tables, large windows offering a city view at dusk.

2. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
United States
Aysha
AED 931
AED 1,024 total
includes taxes & fees
31 Oct - 1 Nov
Waldorf Astoria Panama
A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious lobby with a round coffee table, seating areas, and a large wall clock.
A hotel with a rooftop pool, lounge chairs, and a view of the sea.
A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.

3. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
United States
Jose
AED 1,289
AED 1,418 total
includes taxes & fees
3 Nov - 4 Nov
Sofitel Legend Casco Viejo, Panama City
A modern hotel room with a sofa, a coffee table, a TV mounted on the wall, and a dining area with a table and chairs.
A modern lobby with a staircase, marble flooring, and large windows with tropical plants.
The exterior of the Renaissance Hotel with a modern design, featuring a prominent 'R' logo, a geometric ceiling design, and a well-lit entrance area.
A modern hotel entrance with a prominent 'Renaissance Hotel' sign, a well-lit outdoor area with a wooden structure, and a staircase leading to the upper floors.

4. Renaissance Panama City Hotel

Renaissance Panama City Hotel
Bella Vista
United States
Carlos
AED 466
AED 513 total
includes taxes & fees
9 Oct - 10 Oct
Renaissance Panama City Hotel
A poolside area with lounge chairs and a view of the ocean.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.
A modern building with a symmetrical facade, multiple balconies, and a central atrium with lighting.
A terrace with seating and a view of the ocean.

5. JW Marriott Panama

JW Marriott Panama
San Francisco
United States
Nemanja
AED 996
AED 1,096 total
includes taxes & fees
31 Oct - 1 Nov
JW Marriott Panama
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A spacious lobby with a curved ceiling, a central staircase, and a reception desk.
A spacious hotel lobby with modern furniture, large windows, and a city view.
A modern building with a sign reading 'HYATT REGENCY.'

6. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
United States
Mariah
AED 687
AED 756 total
includes taxes & fees
11 Oct - 12 Oct
Hyatt Regency Panama City
A hotel entrance with a central water feature, seating areas, and potted plants.
A spacious lobby with a wooden ceiling, a central wooden table surrounded by potted plants, and a marble wall with a large window in the background.
The entrance of The Santa Maria with a covered walkway and a view of the interior.
An outdoor dining area with wicker chairs and tables, a bar with bottles, and a pool in the background.

7. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
United States
Shelly-Ann
AED 851
AED 936 total
includes taxes & fees
31 Oct - 1 Nov
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A modern high-rise building with a prominent 'W' logo, surrounded by other buildings and a busy street at night.
A modern hotel room with a large bed, a desk, a chair, and a view of the cityscape.
A high-rise building with a rooftop pool area, surrounded by other buildings.

8. W Panama

W Panama
Bella Vista
United States
Naomi
AED 849
AED 934 total
includes taxes & fees
1 Nov - 2 Nov
W Panama
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A marina with boats docked, a city skyline with illuminated buildings, and a visible moon in the sky.
A modern bar area with seating and a view of the city.
A modern interior with a spiral staircase, a large window, and a seating area.

9. Hilton Panama

Hilton Panama
Bella Vista
United States
Simon
AED 931
AED 1,024 total
includes taxes & fees
2 Nov - 3 Nov
Hilton Panama
A hotel with a pool, beach, and palm trees.
A spacious lobby with a modern design, featuring a central seating area with sofas and ottomans, surrounded by large, open spaces and natural light.
A beachfront hotel with a large building, a beach, and a clear sky.
A large hotel with multiple towers, a central courtyard with a swimming pool, and surrounding landscaped areas.

10. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
Veracruz
United States
Anna
AED 757
AED 833 total
includes taxes & fees
12 Oct - 13 Oct
The Westin Playa Bonita Panama
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.
A person performing a yoga pose in a living room with a large window and a sofa.
A rooftop swimming pool with a cityscape view, glass railings, and a modern architectural design.
A cozy outdoor seating area with a wooden bench and white tables, surrounded by lush greenery and potted plants.

11. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
Bella Vista
United States
Juliet
AED 777
AED 855 total
includes taxes & fees
4 Oct - 5 Oct
Bristol Panama, a Registry Collection Hotel
Lobby
Breakfast area
Banquet hall
Bar (on property)

12. Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
Bella Vista
United States
Aldo
AED 384
AED 425 total
includes taxes & fees
4 Oct - 5 Oct
Waymore Hotel Spa and Casino
Terrace/patio
Room
Outdoor pool
Casino

13. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
MARVIN
AED 784
AED 866 total
includes taxes & fees
29 Oct - 30 Oct
Megapolis Hotel Panamá
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama Canal Zone.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
AED 514
AED 590 total
9 Oct - 10 Oct
includes taxes & fees
Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama
AED 699
AED 768 total
5 Oct - 6 Oct
includes taxes & fees
9/10 Wonderful! (1,002 reviews)
Central Hotel Panama Casco Viejo
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Avenida Balboa Panama City
AED 531
AED 584 total
26 Oct - 27 Oct
includes taxes & fees
8.6/10 Excellent! (1,759 reviews)
Megapolis Hotel Panamá
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Learn more about Panama Canal Zone

Explore the relaxing area of Panama Canal Zone—natural beauty, golf courses, and popular sights like Albrook Shopping Mall.

See all hotels in Panama Canal Zone
A large suspension bridge, industrial cranes, and a calm river.

Top Panama Canal Zone Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Si"
Otto 1-night trip
Posted 7 hours ago
Hotel Riu Plaza Panama

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Panama Canal Zone?
The amount you pay for a 5-star hotel in Panama Canal Zone can vary depending on when you decide to travel and how long you plan to be away, among a range of factors. Use our price per night filter and other search tools to score the best deal on a high-end getaway.
  • Search for the lowest price per night from AED 584
What makes a hotel 5 stars in Panama Canal Zone?
In Panama Canal Zone, a hotel needs to offer a certain amount of upscale amenities to be designated 5 stars. These can include gourmet restaurants, saunas and spas, on-site gyms, premium bedding, complimentary luxury toiletries and more. What also sets 5-star hotels apart is their guest-focused standard of service. You can look forward to things like nightly turn-down services, concierge services and in-room massages. Some may also offer extra touches such as welcome gifts.
Are there any 5-star all-inclusive resorts in Panama Canal Zone?
Our filter tool is the quickest way to find exactly what you want. Select "All inclusive" and "5-star" to see the most upscale resorts in Panama Canal Zone where your accommodations, meals, entertainment and activities are included in the price. At these escapes, your trip is pure leisure from the moment you check in.