
Find 5 Star Hotels in Southern Indiana from AED 542
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check availability on Southern Indiana 5 Star Hotels
Tonight
10 Oct - 11 OctTomorrow
11 Oct - 12 OctNext weekend
16 Oct - 18 OctIn two weeks
23 Oct - 25 OctSave an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Southern Indiana.

Galt House Hotel Trademark Collection by Wyndham
140 North Fourth Street Louisville KY
AED 533
AED 627 total
25 Oct - 26 Oct
includes taxes & fees
9/10 Wonderful! (4,357 reviews)

Omni Louisville Hotel
400 S. 2nd Street Louisville KY
AED 933
AED 1,098 total
30 Oct - 31 Oct
includes taxes & fees

The Brown Hotel
335 W Broadway Louisville KY
AED 460
AED 542 total
28 Oct - 29 Oct
includes taxes & fees
9.4/10 Exceptional! (1,358 reviews)
Still don't see what you're looking for?
See all properties in Southern Indiana.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Southern Indiana
Live music, casinos, and sights from Patoka Lake Swimming Beach to Patoka Lake—discover it all in Southern Indiana.
See all hotels in Southern Indiana
Top Southern Indiana Hotel Reviews
Frequently asked questions
How much does it cost to stay in a 5-star hotel in Southern Indiana?
The amount you pay for a 5-star hotel in Southern Indiana can vary according to when you want to travel and how long you plan to stay, among a range of factors. Use our price per night filter and other search tools to score the best deal on a high-end stay.
- Search for the lowest price per night from AED 542
What makes a hotel 5 stars in Southern Indiana?
Exemplary guest service is the hallmark of every 5-star hotel in Southern Indiana. From the minute you arrive, staff cater to your every whim, whether answering room service calls 24/7 or providing in-room massages. What's more, hotels must feature upscale amenities to be entitled to a 5-star rating. These can include deluxe baths, saunas or spas, swimming pools, fine dining kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Southern Indiana?
Our filters are the quickest way to narrow down what you want. Select "All inclusive" and "5-star" to see the most luxurious hotels in Southern Indiana where your meals, lodging, entertainment and activities are included in the upfront price. At these stays, your vacation is pure leisure from the moment you arrive.