Find hotels in Defiance, MO from AED 231

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30 Jun - 1 Jul
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1 Jul - 2 Jul
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4 Jul - 6 Jul
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11 Jul - 13 Jul

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Compare 818 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Crowne Plaza St. Louis Airport by IHG
Lobby sitting area

Crowne Plaza St. Louis Airport by IHG

3.5 star property
  • Pool
  • Free airport shuttle
  • Free WiFi
  • Restaurant
  • Air conditioning
  • Gym
8.0 out of 10, Very Good, (1004)
  • cleanliness
    Travelers can unwind at the indoor pool with sun loungers or hit the gym before exploring the entertainment options at nearby Westport Plaza

What verified guests said

"Great stay "

Crowne Plaza St. Louis Airport by IHG highlights

Crowne Plaza St. Louis Airport, near Hollywood Casino Amphitheatre, offers a practical base. Cloud's Restaurant serves breakfast, and the bar is great for evening drinks. Enjoy the 24-hour business center, free in-room WiFi, and attentive staff.
The price is AED 424
AED 504 total
includes taxes & fees
20 Jul - 21 Jul
Crowne Plaza St. Louis Airport by IHG
MainStay Suites St Louis Airport
Free daily buffet breakfast

MainStay Suites St Louis Airport

3.0 star property
  • Breakfast included
  • Parking included
  • Free WiFi
  • Air conditioning
  • Gym
  • Parking available
8.2 out of 10, Very Good, (285)
  • cleanliness
    Travelers find the perfect blend of convenience and leisure with on-site shopping and nearby golfing at this airport-adjacent retreat

What verified guests said

"Always a safe convenient place to stay "

MainStay Suites St Louis Airport highlights

MainStay Suites St Louis Airport offers a practical location near the airport with thoughtful amenities. Enjoy a breakfast buffet, 24-hour gym, horseback riding, free in-room WiFi, and on-site dry cleaning for a comfortable stay.
The price is AED 380
AED 453 total
includes taxes & fees
2 Jul - 3 Jul
MainStay Suites St Louis Airport
Comfort Inn St. Louis Airport
Lobby

Comfort Inn St. Louis Airport

3.0 star property
  • Breakfast included
  • Parking included
  • Free WiFi
  • Air conditioning
  • Gym
  • Business services
8.6 out of 10, Excellent, (865)
  • cleanliness
    Guests start their day with a complimentary breakfast buffet before tackling work in the business center or keeping fit in the 24-hour gym

What verified guests said

"I had a great stay"

Comfort Inn St. Louis Airport highlights

Comfort Inn St Louis – Airport welcomes travelers with a hearty breakfast buffet each morning. Practical amenities include laundry facilities and a 24/7 gym. In-room WiFi keeps everyone connected, and the attentive staff consistently earns positive reviews from guests.
The price is AED 331
AED 395 total
includes taxes & fees
6 Jul - 7 Jul
Comfort Inn St. Louis Airport
Embassy Suites by Hilton St. Louis Airport
Lobby

Embassy Suites by Hilton St. Louis Airport

3.5 star property
  • Pool
  • Breakfast included
  • Free airport shuttle
  • Pet friendly
  • Parking included
  • Free WiFi
7.6 out of 10, Good, (1001)
  • cleanliness
    Travelers start their day with a complimentary breakfast before handling last-minute details through convenient express check-in and dry cleaning services

What verified guests said

"Breakfast was best "

Embassy Suites by Hilton St. Louis Airport highlights

Embassy Suites by Hilton St. Louis Airport offers a convenient retreat near the airport with free full breakfast and roundtrip shuttle service. Guests can relax in the indoor pool or shop at the on-site grocery store. Attentive staff earn positive reviews.
The price is AED 548
AED 648 total
includes taxes & fees
20 Jul - 21 Jul
Embassy Suites by Hilton St. Louis Airport
Extended Stay America Select Suites - St. Louis - Airport - Central
Studio, 2 Double Beds, Non Smoking | Desk, free WiFi, bed sheets

Extended Stay America Select Suites - St. Louis - Airport - Central

2.5 star property
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Laundry
  • Microwave
7.0 out of 10, Good, (972)
  • cleanliness
    Travelers can grab a quick breakfast before catching their flight or unwind with a barbecue dinner after exploring the local attractions nearby

What verified guests said

"Clean and had good accommodation "

Extended Stay America Select Suites - St. Louis - Airport - Central highlights

Extended Stay America Suites St Louis Airport Central offers a convenient airport location with practical amenities. Guests enjoy free to-go breakfast, barbecue grills, WiFi, coffee in the lobby, and laundry facilities for a comfortable extended stay.
The price is AED 307
AED 368 total
includes taxes & fees
20 Jul - 21 Jul
Extended Stay America Select Suites - St. Louis - Airport - Central
Hilton St. Louis Frontenac
Lobby

Hilton St. Louis Frontenac

4.0 star property
  • Pool
  • Free airport shuttle
  • Parking included
  • Free WiFi
  • Restaurant
  • Air conditioning
8.8 out of 10, Excellent, (1002)
  • cleanliness
    Travelers can enjoy classic American dishes at Provinces Restaurant or relax poolside after visiting nearby attractions like Forest Park and St. Louis Zoo

What verified guests said

"Great service and great location. "

Hilton St. Louis Frontenac highlights

Hilton St. Louis Frontenac is near iconic city attractions. Enjoy the seasonal outdoor pool for a refreshing break, and savor American cuisine at Provinces Restaurant. A complimentary area shuttle lets you explore nearby landmarks hassle-free.
The price is AED 496
AED 578 total
includes taxes & fees
6 Jul - 7 Jul
Hilton St. Louis Frontenac
La Quinta Inn & Suites by Wyndham St. Louis Westport
Exterior

La Quinta Inn & Suites by Wyndham St. Louis Westport

3.0 star property
  • Pool
  • Breakfast included
  • Free airport shuttle
  • Pet friendly
  • Parking included
  • Free WiFi
7.2 out of 10, Good, (1008)
  • cleanliness
    Travelers start their day with a self-serve breakfast at La Quinta Inn & Suites by Wyndham St. Louis Westport, where the outdoor pool offers afternoon relaxation

What verified guests said

"Staff was great. "

La Quinta Inn & Suites by Wyndham St. Louis Westport highlights

La Quinta Inn & Suites by Wyndham blends comfort with practicality in St. Louis Westport. Guests connect with in-room WiFi throughout their stay, while the on-site gym provides workout options after a day of exploring. The property's self-serve breakfast fuels morning adventures.
The price is AED 340
AED 395 total
includes taxes & fees
28 Jul - 29 Jul
La Quinta Inn & Suites by Wyndham St. Louis Westport
Extended Stay America Select Suites - St. Louis - Westport - E Lackland Rd
Studio, 2 Twin Beds, Non Smoking | Desk, free WiFi, bed sheets

Extended Stay America Select Suites - St. Louis - Westport - E Lackland Rd

2.5 star property
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Laundry
  • Microwave
5.8 out of 10, (1005)

What verified guests said

"Unable to locate the person at the front desk to check in for a hour the first room smells do I ask to switch rooms which was much better."
The price is AED 284
AED 330 total
includes taxes & fees
1 Jul - 2 Jul
Extended Stay America Select Suites - St. Louis - Westport - E Lackland Rd
Red Roof Inn St Louis - Westport/ Maryland Heights
Exterior

Red Roof Inn St Louis - Westport/ Maryland Heights

2.0 star property
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Business services
  • Laundry
5.4 out of 10, (1003)
  • cleanliness
    Travelers stay connected with free WiFi while handling laundry on-site, and the lobby coffee station provides a perfect pre-exploration energy boost

What verified guests said

"Its a quiet little area. Building is a bit run down on.the outside so dont let the appearance discourage you the room are nice. Newly remodeled and comfortable. "

Red Roof Inn St Louis - Westport/ Maryland Heights highlights

The Red Roof Inn St Louis - Westport places visitors in the city's vibrant heart with practical amenities. Enjoy productivity features like a business center, in-room WiFi, and complimentary self-parking for a hassle-free stay.
The price is AED 265
AED 307 total
includes taxes & fees
3 Jul - 4 Jul
Red Roof Inn St Louis - Westport/ Maryland Heights
The Lodge Hotel and Banquets
Terrace/patio

The Lodge Hotel and Banquets

2.0 star property
  • Pool
  • Parking included
  • Free WiFi
  • Air conditioning
  • Business services
  • Laundry
5.0 out of 10, (352)
  • cleanliness
    Travelers can shop to their heart's content at the adjacent retail center before unwinding with a refreshing dip in the hotel's indoor pool

What verified guests said

"Every thing was clean and very nice kept was very wonderful pool "

The Lodge Hotel and Banquets highlights

The Lodge Hotel and Banquets offers relaxation and productivity with an indoor pool and free WiFi. Located in a shopping center, it provides easy access to attractions. Attentive staff create a welcoming atmosphere, making guests feel at home.
The price is AED 253
AED 305 total
includes taxes & fees
1 Jul - 2 Jul
The Lodge Hotel and Banquets
Courtyard by Marriott St Louis Westport Plaza
Exterior

Courtyard by Marriott St Louis Westport Plaza

3.0 star property
  • Parking included
  • Free WiFi
  • Restaurant
  • Air conditioning
  • Gym
  • Breakfast available
8.8 out of 10, Excellent, (1004)
  • cleanliness
    Travelers can enjoy a leisurely breakfast or relax with the morning paper by the lobby fireplace at this conveniently located Westport Plaza hotel

What verified guests said

"The property was clean and the staff was very friendly."

Courtyard by Marriott St Louis Westport Plaza highlights

Located in the business district, Courtyard by Marriott St Louis Westport Plaza offers a peaceful garden setting and welcoming lobby with fireplace. Enjoy American dishes at The Bistro or coffee from the on-site shop. Helpful staff and free WiFi ensure a comfortable stay.
The price is AED 452
AED 524 total
includes taxes & fees
20 Jul - 21 Jul
Courtyard by Marriott St Louis Westport Plaza
Residence Inn St Louis Westport
Exterior

Residence Inn St Louis Westport

3.0 star property
  • Pool
  • Breakfast included
  • Pet friendly
  • Free WiFi
  • Air conditioning
  • Gym
9.2 out of 10, Wonderful, (411)
  • cleanliness
    Travelers relax by the firepit or enjoy a swim at this comfortable, convenient Residence Inn in St Louis Westport's business district

What verified guests said

"Loved it "

Residence Inn St Louis Westport highlights

Frances recommends starting the day with the free full breakfast at Residence Inn St Louis Westport before exploring. The helpful staff offers grocery shopping and a 24-hour front desk. Guests enjoy the indoor pool for swimming and the outdoor firepit for evening relaxation.
The price is AED 559
AED 648 total
includes taxes & fees
27 Jul - 28 Jul
Residence Inn St Louis Westport
Fairfield Inn & Suites St Louis Westport
Exterior

Fairfield Inn & Suites St Louis Westport

2.5 star property
  • Pool
  • Breakfast included
  • Free WiFi
  • Air conditioning
  • Gym
  • Parking available
9.2 out of 10, Wonderful, (781)
  • cleanliness
    Travelers fuel up for meetings or adventures at this Westport hotel, where relaxation by the firepit balances perfectly with workouts in the fitness center

What verified guests said

"Fairfiled Inn has always been very reliable, clean and comfortable and great breakfast options"

Fairfield Inn & Suites St Louis Westport highlights

The Fairfield Inn & Suites St Louis Westport welcomes guests in the business district. Start your day with a complimentary breakfast buffet. After a busy day, refresh in the indoor pool or unwind by the outdoor firepit.
The price is AED 492
AED 571 total
includes taxes & fees
20 Jul - 21 Jul
Fairfield Inn & Suites St Louis Westport
Extended Stay America Select Suites St Louis Westport Craig
Studio, 2 Queen Beds, Non Smoking | Desk, laptop workspace, iron/ironing board, free WiFi

Extended Stay America Select Suites St Louis Westport Craig

2.5 star property
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Business services
  • Laundry
6.4 out of 10, (750)
  • cleanliness
    Travelers stay connected with complimentary WiFi and parking at this suburban hotel where laundry facilities make extended stays more comfortable

What verified guests said

"Great hotel quiet friendly staff will always come back when im in the area"

Extended Stay America Select Suites St Louis Westport Craig highlights

Extended Stay America Select Suites St Louis Westport Craig is a quiet suburban hotel ideal for long visits. It offers conference space, free WiFi, self-parking, and on-site laundry facilities for convenience and routine maintenance.
The price is AED 301
AED 349 total
includes taxes & fees
30 Jul - 31 Jul
Extended Stay America Select Suites St Louis Westport Craig
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Lobby

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

2.5 star property
  • Pool
  • Breakfast included
  • Parking included
  • Free WiFi
  • Air conditioning
  • Gym
4.6 out of 10, (1008)
  • cleanliness
    Travelers find comfort just steps from Hollywood Casino Amphitheatre with morning coffee options and fitness facilities to keep routines intact

What verified guests said

"Enjoyed staying "

Days Inn and Suites by Wyndham St. Louis/Westport Plaza highlights

Located near Westport Plaza, Days Inn and Suites by Wyndham St. Louis/Westport Plaza offers convenient amenities. Enjoy a to-go breakfast, library, laundry facilities, outdoor pool, in-room WiFi, and attentive staff for a pleasant stay.
The price is AED 244
AED 282 total
includes taxes & fees
27 Jul - 28 Jul
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Courtyard by Marriott St Louis Creve Coeur
Lobby

Courtyard by Marriott St Louis Creve Coeur

3.0 star property
  • Parking included
  • Free WiFi
  • Restaurant
  • Air conditioning
  • Gym
  • Breakfast available
8.6 out of 10, Excellent, (1003)
  • cleanliness
    This welcoming hotel near Westport Plaza offers a perfect mix of relaxation options - from gathering around the firepit to enjoying a fresh coffee in the café

What verified guests said

"Great place to stay! Lots of options for food and shopping. "

Courtyard by Marriott St Louis Creve Coeur highlights

Located near Hollywood Casino and Westport Plaza, Courtyard by Marriott St Louis Creve Coeur offers thoughtful comfort. Guests can relax by the outdoor firepit, grab coffee at the café, or enjoy dinner at The Bistro. The helpful staff consistently earns positive reviews.
The price is AED 419
AED 487 total
includes taxes & fees
27 Jul - 28 Jul
Courtyard by Marriott St Louis Creve Coeur
Comfort Inn St. Louis - Westport Event Center
Lobby

Comfort Inn St. Louis - Westport Event Center

3.0 star property
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
7.0 out of 10, Good, (1005)
  • cleanliness
    Travelers start their day with a complimentary breakfast buffet at this convenient hotel, then relax by the fireplace or head out to explore St. Louis attractions

What verified guests said

"Plently of dining options close by. Parking was easy. Staff was nice, friendly and helpful. Would stay here again. "

Comfort Inn St. Louis - Westport Event Center highlights

The Comfort Inn St. Louis - Westport Event Center offers a welcoming atmosphere with practical amenities. Guests enjoy garden views, a lobby fireplace, in-room WiFi, and convenient dry cleaning. The free breakfast buffet helps travelers prepare for their day.
The price is AED 344
AED 399 total
includes taxes & fees
6 Jul - 7 Jul
Comfort Inn St. Louis - Westport Event Center
Best Western Plus St. Louis West-Westport
Lobby

Best Western Plus St. Louis West-Westport

2.5 star property
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
8.0 out of 10, Very Good, (1007)
  • cleanliness
    Travelers begin their day with a complimentary full breakfast before lounging by the pool or tackling work projects in the well-equipped business center.

What verified guests said

"Clean, quiet, safe"

Best Western Plus St. Louis West-Westport highlights

The Best Western Plus St. Louis West-Westport is centrally located, offering practical amenities for relaxation and productivity. Guests can maintain their exercise routine in the gym, swim in the pool, or use the convenient dry cleaning and laundry services during their stay.
The price is AED 360
AED 417 total
includes taxes & fees
14 Jul - 15 Jul
Best Western Plus St. Louis West-Westport
Hampton Inn St. Louis/Westport
Standard Room, 2 Double Beds, Non Smoking | In-room safe, desk, laptop workspace, iron/ironing board

Hampton Inn St. Louis/Westport

2.5 star property
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
7.8 out of 10, Good, (947)
  • cleanliness
    Business travelers find everything they need at this Westport hotel, from a hearty breakfast buffet to high-speed WiFi and a 24-hour gym for energizing workouts

What verified guests said

"Great communication from staff."

Hampton Inn St. Louis/Westport highlights

Located in the heart of the business district, Hampton Inn St. Louis/Westport offers a practical stay with essential conveniences. Enjoy the breakfast buffet each morning, use dry cleaning services, and unwind in the seasonal outdoor pool after a productive day.
The price is AED 371
AED 431 total
includes taxes & fees
20 Jul - 21 Jul
Hampton Inn St. Louis/Westport
Extended Stay America Suites St Louis Westport Central
Terrace/patio

Extended Stay America Suites St Louis Westport Central

2.5 star property
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Gym
7.4 out of 10, Good, (962)
  • cleanliness
    Travelers can stay productive at this suburban St. Louis hotel where outdoor grills provide relaxation after workouts in the 24-hour gym

What verified guests said

"Great place "

Extended Stay America Suites St Louis Westport Central highlights

Extended Stay America Suites St Louis Westport Central offers practical comforts for longer stays. Guests start their mornings with to-go breakfast and free WiFi. The hotel provides convenient laundry facilities and barbecue grills for unwinding after busy days.
The price is AED 314
AED 364 total
includes taxes & fees
6 Jul - 7 Jul
Extended Stay America Suites St Louis Westport Central
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Defiance

Trip time! Discover the wineries, parks, and history in Defiance.

See all hotels in Defiance

Frequently asked questions

What's the best place to stay in Defiance?

Hollywood Casino & Hotel St. Louis, located 18.1 mi (29.2 km) from the heart of Defiance, is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West and Wingate by Wyndham St. Louis/Fenton Route 66. See all available top hotels, or vacation rentals in Defiance.

What's the top vacation rental in Defiance?

St. Charles 1860's Gem - Sleeps 6!: Visitors like this Defiance vacation home rental. It is located on a river and has a garden, a selection of books, and air-conditioning to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in Defiance.

If I need to cancel my hotel reservation in Defiance, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.

Where can I learn more about changing or cancelling my trip to Defiance?

For more information about changing or cancelling your trip to Defiance, head over to our customer service page.

Where is the best hotel to stay with easy access to August A. Busch Memorial Conservation Area?

Sleep Inn & Suites O'Fallon MO - Technology Drive is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 2.6 mi (4.3 km) from August A. Busch Memorial Conservation Area. Other good options within a few miles include Hilton Garden Inn St. Louis/O'Fallon MO and Holiday Inn Express St. Louis West - O'Fallon, an IHG Hotel.

What about the best place to stay near Chandler Hill Vineyards?

One of the top choices for your stay is The Wildwood Hotel, located 10 mi (16.1 km) from Chandler Hill Vineyards, and this 3.5-star hotel offers free breakfast and an indoor pool.

What are some accommodations with pools in Defiance?

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West: Hotel, 14-minute walk from Hollywood Casino Amphitheatre. Offers daily, an indoor pool, and complimentary wired internet access. Wingate by Wyndham St. Louis/Fenton Route 66 and The Wildwood Hotel are two additional hotels that offer an onsite pool. View all hotels with pools in Defiance.

What's the best place to stay near Lambert-St. Louis International Airport (STL)?

Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.

What's it like to stay in Defiance?

Visitors can enjoy all that Defiance has to offer including the wineries and parks. Top sights in the area include Busch Stadium, St. Louis Union Station, and Enterprise Center. In Defiance, there are 20 hotels and other accommodations to choose from. Find out more about Defiance.

What is there to see in Defiance?

Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River, and Matson Hill Park Trailhead. A couple of additional sights to add to your agenda are Yellow Farmhouse Winery and Chandler Hill Vineyards. Check out what more to see and do in Expedia's Defiance guide.

What's the seasonal weather like in Defiance?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.