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Our top choices for Santa Ana hotels

1. Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (102 reviews)
"Always an amazing stay"
United States
chris
The price is AED 277
AED 416 total
includes taxes & fees
6 Aug - 7 Aug
Casco View Apartments

2. Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (73 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is AED 103
AED 114 total
includes taxes & fees
3 Aug - 4 Aug
Hostal La Cigarra

3. Hotel República

Hotel República
2.0 star property
Santa Ana
6.8 out of 10, (196 reviews)
"Good location. Walking distance to shops and public transport."
Canada
Danilo
The price is AED 96
AED 327 total
includes taxes & fees
1 Sep - 2 Sep
Hotel República

4. La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood
3.0 star property
Santa Ana
7.6 out of 10, Good, (18 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is AED 278
AED 406 total
includes taxes & fees
2 Aug - 3 Aug
La Manzana Barrio Vivo by Wynwood

5. Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
The price is AED 94
AED 104 total
includes taxes & fees
2 Aug - 3 Aug
Hotel Riazor

6. ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (11 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is AED 90
AED 99 total
includes taxes & fees
29 Aug - 30 Aug
ART CASCO The Hotel

7. Hotel Caracas - Casco Viejo

Hotel Caracas - Casco Viejo
3.0 star property
Santa Ana
9.0 out of 10, Wonderful, (2 reviews)
"It is what you would expect for the $30/ night. Clean bed, and room, a/c worked well, limited water for showers at times, limited hot water. Great location for walking around close to Casco Viejo."
United States
William
The price is AED 95
AED 105 total
includes taxes & fees
24 Aug - 25 Aug
Hotel Caracas - Casco Viejo

8. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
21.1 km from Santa Ana
8.6 out of 10, Excellent, (2,621 reviews)
"Excellent hotel and convenient to Tocumen airport."
United States
James
The price is AED 481
AED 554 total
includes taxes & fees
6 Aug - 7 Aug
Crowne Plaza Panama Airport by IHG

9. ORHO Hotel Boutique 15 Minutes from PTY Airport

ORHO Hotel Boutique 15 Minutes from PTY Airport
2.0 star property
20.5 km from Santa Ana
8.8 out of 10, Excellent, (169 reviews)
"Staff were friendly, helpful and always accommodating."
United States
Laurence
The price is AED 366
AED 478 total
includes taxes & fees
1 Sep - 2 Sep
ORHO Hotel Boutique 15 Minutes from PTY Airport

10. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
19.8 km from Santa Ana
8.4 out of 10, Very Good, (1,809 reviews)
"great location and friendly staff. Hotel provided airport shuttle was a bonus - staff knew departure times and coordinated checkout with the shuttle departure."
United States
Celia Rosa
The price is AED 390
AED 429 total
includes taxes & fees
5 Aug - 6 Aug
Riande Aeropuerto Hotel & Casino

11. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
14.7 km from Santa Ana
9.0 out of 10, Wonderful, (1,002 reviews)
"Enjoyed my short stay"
United States
Chantelle
The price is AED 359
AED 395 total
includes taxes & fees
14 Aug - 15 Aug
Courtyard by Marriott Panama Metromall

12. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz, 12.7 km from Santa Ana
9.6 out of 10, Exceptional, (721 reviews)
"Excellent hotel conveniently located just 15 min away from Tocumen airport. Not far from downtown. 15 min without traffic. Rooms were nice and beds super comfy. Hotel restaurant was good and staff very professional and friendly. Would definitely stay again."
United States
Carlos
The price is AED 989
AED 1,088 total
includes taxes & fees
14 Aug - 15 Aug
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

13. Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
4.0 star property
Costa del Este, 10.2 km from Santa Ana
9.4 out of 10, Exceptional, (333 reviews)
"This is a great stay , property is very quiet and peaceful highly recommend"
United States
kenron
The price is AED 354
AED 583 total
includes taxes & fees
3 Aug - 4 Aug
Corporate Stays Arcadia | Executive Furnished Apartments

14. The Westin Panama

The Westin Panama
4.0 star property
Costa del Este, 9.4 km from Santa Ana
9.0 out of 10, Wonderful, (339 reviews)
"Amazing area and hotel"
United States
Kendall
The price is AED 787
AED 865 total
includes taxes & fees
22 Aug - 23 Aug
The Westin Panama

15. Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco, 5.7 km from Santa Ana
8.6 out of 10, Excellent, (1,004 reviews)
"Very nice stay, walking distance to Multi Plaza mall"
United States
Sergio
The price is AED 628
AED 691 total
includes taxes & fees
8 Aug - 9 Aug
Sheraton Grand Panama

16. Aloft by Marriott Panama

Aloft by Marriott Panama
3.5 star property
San Francisco, 5.7 km from Santa Ana
8.8 out of 10, Excellent, (1,001 reviews)
"Everything was awesome , 10/10 stay"
United States
Javannah
The price is AED 436
AED 480 total
includes taxes & fees
14 Aug - 15 Aug
Aloft by Marriott Panama

17. JW Marriott Panama

JW Marriott Panama
5.0 star property
Punta Pacifica, 4.3 km from Santa Ana
9.0 out of 10, Wonderful, (1,000 reviews)
"Hotel was clean and staff was very helpful."
United States
Benjamin A
The price is AED 937
AED 1,031 total
includes taxes & fees
29 Aug - 30 Aug
JW Marriott Panama

18. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco, 5.1 km from Santa Ana
9.6 out of 10, Exceptional, (1,280 reviews)
"Is a great hotel"
United States
Raoel
The price is AED 459
AED 505 total
includes taxes & fees
2 Aug - 3 Aug
Ramada Plaza by Wyndham Panama Punta Pacifica

19. Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
Punta Paitilla, 4 km from Santa Ana
9.2 out of 10, Wonderful, (660 reviews)
"Everything was perfect, breakfast was good with many options and the fruits amazing, staff are very friendly and helpful, I really recommend this hotel."
United States
Frank David Delgado
The price is AED 823
AED 905 total
includes taxes & fees
21 Aug - 22 Aug
Residence Inn by Marriott Panama City

20. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 3.4 km from Santa Ana
9.4 out of 10, Exceptional, (2,220 reviews)
"Great breakfast, location excellent, staff friendly and spacious room"
United States
Gilberto
The price is AED 379
AED 417 total
includes taxes & fees
18 Aug - 19 Aug
Plaza Paitilla Inn Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers
Casco View Apartments
3.5 star property
9.0
Wonderful
102 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
73 reviews
View
Twin Room | In-room safe, desk, soundproofing, WiFi (free)
Hotel República
2.0 star property
6.8
196 reviews
View
Front of property
ART CASCO The Hotel
2.0 star property
6.0
11 reviews
View
Exterior
Hotel Caracas - Casco Viejo
3.0 star property
9.0
Wonderful
2 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Pacific Center while you're in town.

Top Santa Ana Hotel Reviews

Find out more about Santa Ana

Top reasons to visit Santa Ana

  • Vibrant Nightlife: Experience the lively bar scene in Santa Ana, perfect for those looking to enjoy Panama City's nightlife.
  • Cultural Attractions: Visit historical sites such as Santa Ana Casco Viejo and local museums to immerse yourself in Panama's rich heritage.
  • Stunning Views: Enjoy picturesque hilltop views that provide a breathtaking backdrop for your vacation.
  • Family-Friendly Activities: Explore various attractions and parks that cater to visitors of all ages.
  • Diverse Accommodations: Choose from a range of hotels and apartments that meet different needs and preferences.

Find great hotels near Santa Ana

Santa Ana offers a diverse selection of accommodations, including hotels and apartments, perfect for every traveler. Whether you seek a pet-friendly stay, a business-friendly environment, or a relaxed vacation experience, you'll find suitable options. With popular choices like Hotel El Panama and various city-themed hotels, Santa Ana is an ideal base for exploring Panama City while enjoying modern amenities and a welcoming atmosphere.

  • Central Hotel Panama Casco Viejo: Experience romance and luxury at the Central Hotel Panama Casco Viejo, a 4-star gem located a mere 805m from Santa Ana. This hotel is an ideal choice for couples seeking a romantic getaway, featuring enticing romance packages and exquisite food and beverage services, including 24-hour room service and champagne service. Guests can indulge in rejuvenating spa treatments, with amenities like facial treatments and a full-service spa available. The hotel’s central location makes it a perfect base for exploring the vibrant city while enjoying a serene retreat.
  • American Trade Hotel: The American Trade Hotel, a stylish 4.5-star property located 644m from Santa Ana, caters to business travelers and pet owners alike. This city-themed hotel provides a blend of comfort and convenience, allowing some pets on-site with waived fees for service animals. Guests can enjoy modern amenities and a prime location in the heart of the city, making it easy to conduct business or explore nearby attractions. With its elegant design and thoughtful services, the American Trade Hotel is perfect for those combining work and leisure.
  • Innfiniti Hotel & Suites: Offering a welcoming atmosphere, the Innfiniti Hotel & Suites is a 3.5-star accommodation located 1.4km from Santa Ana. This city-themed hotel is tailored for business travelers, providing essential amenities and a convenient location in the bustling city center. With comfortable rooms and a focus on guest satisfaction, Innfiniti is an excellent choice for those looking to balance work and relaxation during their stay in Panama City.

Where to stay near Santa Ana

Santa Ana, a vibrant neighborhood in Panama City, offers a unique blend of family-friendly attractions and business opportunities. Visitors can enjoy the welcoming atmosphere and explore nearby areas that showcase the rich culture of Panama. From local markets to luxurious accommodations, Santa Ana caters to all types of travelers seeking relaxation or adventure. Immerse yourself in the charm of this lively neighborhood while discovering the diverse experiences that Panama City has to offer.

  • Panama City: The vibrant heart of Panama, Panama City boasts a unique blend of modern skyscrapers and historic neighborhoods. Santa Ana is situated within its bustling limits, making it a convenient base for your adventures. Travelers flock here year-round, with peak visits in January, July, and September, drawn by its family-friendly atmosphere and urban experiences. Don't miss the chance to explore shopping centers and malls, while local attractions like beaches, parks, and lively streets offer a perfect backdrop for relaxation and exploration.
  • Casco Viejo: Just 644m from Santa Ana, Casco Viejo is a historic neighborhood filled with charming cobblestone streets and colonial architecture. This area is particularly popular in January and the spring months, catering to families and outdoor enthusiasts alike. Visitors can indulge in shopping at local markets and enjoy the vibrant atmosphere of cafes and restaurants. With close proximity to beautiful parks and stunning beachfront views, Casco Viejo is a must-visit for those looking to soak in the culture and history of Panama City.
  • San Felipe: Also located 644m from Santa Ana, San Felipe is known for its rich history and cultural landmarks. This neighborhood attracts families and outdoor lovers, especially during peak seasons in February, March, and December. Explore local resorts and shopping areas, and take a leisurely stroll through picturesque parks or along the beach. With historic sites nearby, San Felipe offers a delightful mix of recreation and education, making it an enriching stop on your Panama journey.

Things to do near Santa Ana

Santa Ana offers a vibrant mix of family-friendly and business-themed activities perfect for any traveler. Explore nearby shopping malls and centers, or indulge in the local bar crawl to experience Panama City's lively nightlife. Whether you're looking to shop or enjoy entertainment, Santa Ana provides a variety of options to make your vacation enjoyable and memorable.

Shopping

For a great shopping experience in Santa Ana, visit Albrook Shopping Mall, just 1.6km away, offering a mix of entertainment and family vibes. Avenida Central, only 483m away, features a lively atmosphere, while Uruguay Street, 3.2km away, is perfect for exploring local shops.

Recreation

In Santa Ana, you can visit Maracana Stadium for an energetic atmosphere, perfect for sports enthusiasts. Estadio Rommel Fernandez and Estadio Nacional Rod Carew offer vibrant sports experiences, making them excellent spots to enjoy local games and immerse yourself in Panama's sports culture.

Adventure

Explore the Honeycreeper Ridge Trail, a stunning hiking trail 43.5km from Santa Ana, offering breathtaking scenery and a chance to connect with nature. For an adrenaline rush, visit Gatun Eco Adventures, a thrilling zipline ropes course located 48.3km away, perfect for adventure seekers.

Nightlife

In Santa Ana, the vibrant nightlife features venues like the National Theater, Anita Villalaz Theater, and Amador Theater, all within 1.6km's reach. Each offers a unique blend of romance, culture, and entertainment, making for an enchanting evening in Panama City.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Ana

To save money on your trip to Santa Ana, consider visiting between September and November, when prices are lower. Book your stay on a Tuesday for the best rates, as Saturdays tend to be the most expensive. Use Expedia’s search tool to filter options by budget and location, and arrange results from lowest to highest price. Additionally, combining hotel reservations with flights and activities through an Expedia package deal can lead to significant savings. Don't forget to look for expedia coupons to maximize your budget.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Santa Ana are September to November, where the prices are slightly lower. This is in comparison to January and March to April, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Santa Ana is Tuesday. The most expensive day to stay around Santa Ana is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your preferences, such as your budget, desired location, and the type of hotel you’re looking for. To find the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel reservations in Santa Ana with your flights and activities through an Expedia package deal.

Find the best attractions near Santa Ana

Santa Ana offers a delightful mix of family-friendly, city-themed, and business vacation options. Visitors can explore fascinating attractions like hilltop views, history museums, and cathedrals. Key points of interest include Santa Ana Casco Viejo, Plaza Santa Ana, Panama City Beach, Santa Ana Square, and Playa Bonita. These sites provide a rich cultural experience, stunning scenery, and a taste of local history, ensuring a memorable visit for travelers.

  • Metropolitan Cathedral of Panama: An architectural marvel, this cathedral features stunning colonial design and intricate details. Visitors can immerse themselves in the rich history and vibrant cultural atmosphere that surrounds this sacred space.
  • Interoceanic Canal Museum: Delve into the fascinating history of the Panama Canal at this engaging museum. With interactive exhibits and informative displays, you'll gain insights into the canal's significance and impact on global trade and travel.
  • Ancon Hill: Offering breathtaking panoramic views of Panama City and the canal, Ancon Hill is perfect for outdoor enthusiasts. Enjoy a scenic hike or leisurely stroll amidst lush greenery and diverse wildlife, making it a peaceful retreat from urban life.

Best time to go to Santa Ana

The best time to visit Santa Ana can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santa Ana falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around Santa Ana falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.8°F (26.0°C)No RainMostly SunnyAverageSlightly High
February79.2°F (26.2°C)No RainMostly SunnySlightly HighAverage
March79.7°F (26.5°C)No RainMostly SunnySlightly HighSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageSlightly High
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudySlightly LowAverage
July79.3°F (26.3°C)Frequent RainMostly CloudyAverageAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly LowSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudyAverageSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly HighAverage

The nearest major airports for your trip to Santa Ana

Traveling to Santa Ana, Panama is convenient with access to major airports. Panama City (PTY-Tocumen Intl.) is located 20.9km away, with nearby hotels like The Santa Maria, a Luxury Collection Hotel, 8.0km from the airport, and JW Marriott Panama, 16.1km away. Alternatively, Panama City (PAC-Marcos A. Gelabert Intl.) is only 3.2km from Santa Ana, featuring excellent accommodations such as Waldorf Astoria Panama and Sofitel Legend Casco Viejo, both within 3.2km of the airport. For a more remote option, Rio Hato (RIH-Scarlett Martinez Intl.) is 91.7km away, with resorts like The Buenaventura Golf & Beach Resort offering transport services to the airport.

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Avenida Balboa and El Machetazo Santa Ana while you're in the neighborhood.
Where is the best hotel for a stay in Santa Ana?
Based on our traveler data, Casco View Apartments is one of the top choices for your stay in Santa Ana. This condo is a short 8-minute walk from Avenida Balboa, and it offers an outdoor pool and in-room kitchens.
How many hotels can I expect to find in Santa Ana?
Expedia has 122 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.
What is there to do in this Panama City neighborhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.