Domus 21 Luxury Suites

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Luxury
VIP Access
9.6

Exceptional

Historic elegance in Rome's heart

Amidst Rome's Historic District, this boutique hotel offers a serene escape with modern, stylish interiors and ancient frescoes. Enjoy spacious rooms, luxurious bath products, and attentive service, all within walking distance of iconic landmarks like the Trevi Fountain and Pantheon.

Popular amenities

  • Pet friendly
  • Free WiFi
  • Air conditioning
  • Laundry
  • Housekeeping
The current price is AED 497
AED 588 total
includes taxes & fees
17 Nov - 18 Nov

Room options

Available filters for rooms
Showing 4 of 4 rooms

View all photos for Superior Room, 1 Queen Bed, Courtyard View

A hotel room with a bed, a desk, a chair, a TV, and a window with a view.

Superior Room, 1 Queen Bed, Courtyard View

10.0 out of 10
Exceptional
(2 reviews)
  • 20 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 Queen Bed
  • Free wired internet

View all photos for Deluxe Room, City View

A hotel room with a large bed, a window with a view of buildings, a small table with a lamp, and a chair.

Deluxe Room, City View

9.8 out of 10
Exceptional
(6 reviews)
  • City view
  • 24 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed OR 2 Twin Beds
  • Free wired internet

View all photos for Junior Suite

A hotel room with a bed, a desk, a chair, a TV, and a window with a view of a building.

Junior Suite

10.0 out of 10
Exceptional
(3 reviews)
  • City view
  • 40 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free wired internet

View all photos for Grand Room

A modern bedroom with a large bed, bedside tables, a mirror, and decorative plants.

Grand Room

  • City view
  • 34 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free wired internet

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1 Nov - 2 Nov
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About the neighborhood

Located in Rome City Centre neighborhood, Domus 21 Luxury Suites is connected to a rail/subway station. Vatican Museums and Castel Sant'Angelo are cultural highlights, and travelers looking to shop may want to visit Via del Corso and Via Veneto. Looking to enjoy an event or a game? See what's going on at Foro Italico or Stadio Olimpico. Be sure not to miss outdoor adventures like mountain biking, ziplining, and skydiving, or hop on a segway rental nearby and take a self-guided tour around the aera. Visit our Rome travel guide
View more Guest Houses in Rome
Map
Corso Vittorio Emanuele II 21, Rome, RM, 00186

What's nearby

  • Ancient ruins with columns and buildings in the background.
    Largo di Torre Argentina
    2 min walk - 0.2 km
  • Teatro Faiano
    1 min walk - 0.0 km
  • Piazza della Minerva
    2 min walk - 0.2 km
  • Chiesa del Gesù
    2 min walk - 0.2 km
  • Crypta Balbi
    2 min walk - 0.2 km

Getting around

  • Venezia Tram Stop
    4 min walk
  • Rome San Pietro Station
    5 min drive
  • Fiumicino - Leonardo da Vinci Intl. Airport (FCO)
    40 min drive

Restaurants

  • Shari Vari
    5 min walk
  • Cafffè Camerino
    5 min walk
  • PASTAEAT la pastapoke
    1 min walk
  • Te Amo
    5 min walk
  • Gigi Rigolatto Roma
    4 min walk

About this property

Domus 21 Luxury Suites

  • Luxury family-friendly guesthouse connected to the convention center
  • A short walk from Pantheon and Campo de' Fiori, Domus 21 Luxury Suites provides dry cleaning/laundry services and more. Guests can connect to free in-room WiFi.
  • Other perks include:
    • A roundtrip airport shuttle (surcharge), an electric car charging station, and express check-out
    • Express check-in, tour/ticket assistance, and free newspapers
    • An elevator, bicycle parking, and smoke-free premises
    • Guest reviews speak highly of the helpful staff
  • Room features
  • All guestrooms at Domus 21 Luxury Suites have comforts such as premium bedding and pillow menus, in addition to thoughtful touches like laptop-compatible safes and air conditioning.
  • Extra amenities include:
    • Highchairs, children's books, and art supplies
    • Reusable coffee/tea filters, recycling, and composting
    • Rainfall showers, designer toiletries, and bidets
    • Childcare services, free infant beds, and electric kettles

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includes taxes & fees
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Frequently asked questions

Is Domus 21 Luxury Suites pet-friendly?

Yes, this property allows cats and dogs (limit 4 total) with a maximum weight of up to 22 lbs per pet.

How much does it cost to stay at Domus 21 Luxury Suites?

As of 23 October 2026, prices found for a 1-night stay for 2 adults at Domus 21 Luxury Suites on 17 November 2026 start from AED 497, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What time is check-in at Domus 21 Luxury Suites?

Check-in start time: 2:00 PM; Check-in end time: 11:00 AM.

What time is check-out at Domus 21 Luxury Suites?

Check-out is at 11:00 AM.

Does Domus 21 Luxury Suites provide a shuttle to the airport?

Yes, there's an airport shuttle that runs on request. A fee of EUR 80 per vehicle applies.

Where is Domus 21 Luxury Suites located?

This family-friendly Rome guesthouse is located near the airport, within a 5-minute walk of Corso Vittorio Emanuele II, Pantheon, and Piazza Venezia. Piazza Navona and Campo de' Fiori are also within 10 minutes. Venezia Tram Stop and Arenula-Cairoli Tram Station are within a 5-minute walk.

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Domus 21 Luxury Suites Reviews

9.6

Exceptional

9.8

Cleanliness

9.4

Amenities

9.8

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 97 out of 116 reviews
Rating 8 - Good. 15 out of 116 reviews
Rating 6 - Okay. 3 out of 116 reviews
Rating 4 - Poor. 0 out of 116 reviews
Rating 2 - Terrible. 1 out of 116 reviews

Reviews

Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great spot. Perfect location.
Stayed 2 nights in Sep 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Our stay at the Domus 21 was great. The staff is excellent. The rooms are beautiful and clean. And the shower is the best anywhere. Thank you
Stayed 3 nights in Sep 2026
Verified review

8/10 Good

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Perfect location, helpful and friendly staff who were brilliant, they contacted us with all the check-in information, offered to arrange our airport transfer. The rooms were clean and comfortable. Would definitely stay there again
Stayed 4 nights in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Would definitely stay here again - staff were very friendly and helpful and was a lovely room in a very convenient location for sightseeing
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Only 7 suites, owner greeted us and our rooms were available upon arrival at 11:30 am. Great restaurants & shopping close. Super experience and will stay here again!
Stayed 2 nights in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Perfect spot for a quick Rome trip. The room was beautiful with high ceilings, the staff were very friendly and helpful with luggage staying after check-out and the location is right in the middle of everything. Perfect!
Stayed 1 night in Jul 2026
Verified review

6/10 Okay

Liked: Cleanliness, staff & service, property conditions & facilities
First of all the entrance is daunting. Everything is by keypad. As a 71 year old once we entered through the old door from the street using the key pad we found ourselves having to carry the luggage up a extra long flight of stairs to get to the rickety old elevator to take us to the fifth floor. Had I known this was a requirement I would not have booked it. This is Definitely accommodation for a much younger traveller. As for the room it was nice, location is great and is well kept. I would recommend the place and increase my stars to 4 but only for the 50 or younger. For the older traveller it can be considered but you need to be somewhat in shape.
Stayed 2 nights in Oct 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely room and host, fantastic location
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Liked: Staff & service, amenities, property conditions & facilities
Room was in a great location! Walking distance from Trevi fountain. Elevator made it easy to go to the 5th floor. Room was huge with high ceilings and a great shower. Will stay again when visiting Rome.
Stayed 2 nights in Jun 2026
Verified review

10/10 Excellent

Perfect location to see all of Rome on foot. Beautiful room. Wonderful helpful staff.
Stayed 3 nights in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Domus 21 was a great combination of modern amenities with old world feel. The historic feel of the property from the street to the entry way is carried over into the room with an excellent fresco on the ceiling along with Roman inspired decorations. While modern feeling with concrete and clean lines, it still feels respectful to the past: the shower feel akin to your own personal Roman bath and the view out the window transports you to another time entirely. I would definitely return to this property the next time my travels bring me to Rome.
Stayed 2 nights in May 2026
Verified review

6/10 Okay

First I will say housekeeping was outstanding.
Stayed 4 nights in Feb 2026
Verified review

8/10 Good

Liked: Cleanliness, staff & service, amenities
Was shown the room and amenities. Great location
Stayed 1 night in Nov 2025
Verified review

10/10 Excellent

Liked: Cleanliness, amenities, property conditions & facilities
Very lovely property! Close to so many restaurants, shopping, bus stops and site seeing.
Stayed 4 nights in Jun 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very good location and stylish
Stayed 2 nights in Nov 2024
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely size rooms that are really clean and quiet. Great location and friendly reception staff
Stayed 4 nights in Oct 2024
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice staff. Great location
Stayed 1 night in Apr 2025
Verified review

8/10 Good

Liked: Cleanliness
Disliked: Staff & service
Overall our stay was alright but we travel often and stay at great places and I wouldn’t call Domus 21 “luxury” if you’re looking for extremely nice accommodations. The positives: Great location, walkable to many tourist sites and tons of shopping and food. Great water pressure and plenty of hot water! Very bright lighting in room. Negatives: Hard to find where to check in- they emailed instructions but it wasn’t marked well with signage in the lobby and the email came the day of check in so many probably do not see the email if traveling. Old and scary elevator lol. Had to separate our party and bags to not put too much weight in it and it stuck once and I was trapped inside but luckily was able to go up a floor again and back down and the doors unlocked that time. Also- you have one staircase to get to the elevator so be prepared to lift your bags up those stairs. Staff is on hand very, very limited hours and was not very welcoming- it is more like an air bnb than a hotel that is staffed. No one around to ask questions etc. For the price and being told the water soda coffee and snacks were complimentary then to he charged 13 euro for two extra nespresso pods and two waters was ridiculous… luxury accommodations include these simple items and we were not told requesting a couple extra would incur a charge until the end. Big deal? No… just not welcoming, and not “luxury”. Room had limited storage for belongings no where to hide luggage… and could be in better condition.
Stayed 2 nights in Sep 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Perfect Stay in Rome

Great location. Super clean. Friendly staff. Comfy bed. Hot shower. Everything I needed for my stay in Rome.
Stayed 1 night in Aug 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent location and service. Even though the hotel doesn't have a 24 hr reception, the staff is invaluable with anything, and the size of the room and location are superb.
Stayed 5 nights in Apr 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Love this hotel!!! Awesome location, very nice inside, beds are super comfortable and staff was friendly and helpful! It also has a lift, which is great when u don’t pack light:-) They do not 24 reception so if you are arriving early or late you will just need to make arrangements.
Stayed 1 night in Oct 2025
Verified review

8/10 Good

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Location, location, location. Great restaurants all around. Walkable to Trevi, the Colosseum and Pantheon.
Stayed 3 nights in Mar 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This is exceptional space to spend time in Rome. The staff and rooms are superior. Their space is very aesthetic and the attention to detail in their design did not go unnoticed. I would not hesitate to stay here again! Thank you for the beautiful accommodations!
Stayed 1 night in Jun 2025
Verified review

8/10 Good

Liked: Cleanliness, staff & service, property conditions & facilities
Fabulous location. Very quiet and peaceful room.
Stayed 4 nights in Sep 2023
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very nice rooms. good location. walkable to colusseum and many nice areas.
Stayed 3 nights in Mar 2024