Default HTG hotel image

Find hotels in Santee, NE from AED 349

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
27 Aug - 28 Aug
Tomorrow
28 Aug - 29 Aug
This weekend
28 Aug - 30 Aug
Next weekend
4 Sep - 6 Sep

Filter by

Star rating

Guest rating

Our top choices for Santee hotels

Family Quadruple Room | Living area | 32-inch LCD TV with digital channels, TV
Family Quadruple Room | Private kitchen | Coffee/tea maker, fridge, microwave, oven
Front of property
Interior detail

1. Lewis and Clark Resort

Lewis and Clark Resort
Yankton
United States
Melissa
AED 331
AED 349 total
includes taxes & fees
8 Sep - 9 Sep
Lewis and Clark Resort
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Top Santee Hotel Reviews

Inviting 3-bedroom house near Gavins Point Dam and Lewis and Clark Lake area.

Inviting 3-bedroom house near Gavins Point Dam and Lewis and Clark Lake area.

10/10 Excellent
"Nice place to stay in Yankton. Close to Gavins Point Dam and to town. Enjoyed our accomodations."
Rebecca P. 3-night trip
Posted 2 days ago
Inviting 3-bedroom house near Gavins Point Dam and Lewis and Clark Lake area.
The Bohemian Bungalow near Main Street in Scenic Verdigre, Nebraska

The Bohemian Bungalow near Main Street in Scenic Verdigre, Nebraska

10/10 Excellent
"The stay was absolutely wonderful! The property was beautiful, clean, comfortable, and exactly as described. The host was friendly, responsive, and made everything easy from check-in to check-out. We had a fantastic experience and would happily stay here again. Highly recommended!"
Anonymous traveler 1-night trip
Posted 3 days ago
The Bohemian Bungalow near Main Street in Scenic Verdigre, Nebraska
Spacious Lakeview Cabin Minutes from Private Beach

Spacious Lakeview Cabin Minutes from Private Beach

10/10 Excellent
"Lots of room for sleeping - open spacious living room with a beautiful lake view."
Kaylee O. 3-night trip
Posted 4 days ago
Spacious Lakeview Cabin Minutes from Private Beach
Lewis and Clark Resort

Lewis and Clark Resort

10/10 Excellent
"This condo was beautiful! Very clean and well maintained. Great location for everything we wanted to do in the Okoboji area. Would definitely stay here again."
Melissa 3-night trip
Posted 9 days ago
Lewis and Clark Resort
Family, friendly country farm home. Enjoying peace and quiet.

Family, friendly country farm home. Enjoying peace and quiet.

10/10 Excellent
"This house had everything we needed for our family’s stay. The kids really enjoyed the garage space. So many things to keep them entertained. House was very clean and AC worked great! So convenient that each family had their own bathroom. Beautiful view from the deck with morning coffee."
Ann B. 2-night trip
Posted 11 days ago
Family, friendly country farm home. Enjoying peace and quiet.
Haven by the Lake

Haven by the Lake

10/10 Excellent
"Great getaway spot with easy access to the state park and its trails and beaches. Our family spent every day at the beach from here."
Jim S. 7-night trip
Posted 11 days ago
Haven by the Lake
Beautiful newly renovated home overlooking Lewis and Clark lake.

Beautiful newly renovated home overlooking Lewis and Clark lake.

10/10 Excellent
"A beautiful home! Enjoyed making memories with our kids and granddaughter!"
Brian T. 4-night trip
Posted 2 weeks ago
Beautiful newly renovated home overlooking Lewis and Clark lake.
Fully furnished lake house with cozy spaces, full kitchen, and lake views.

Fully furnished lake house with cozy spaces, full kitchen, and lake views.

10/10 Excellent
"Very accommodating."
Jason W. 3-night trip
Posted 2 weeks ago
Fully furnished lake house with cozy spaces, full kitchen, and lake views.
Cozy cabin near Lewis and Clark Lake and CJ’s at the Lake

Cozy cabin near Lewis and Clark Lake and CJ’s at the Lake

10/10 Excellent
"Checked all the boxes for what we needed for this stay, thanks Tony !"
Sheena A. 2-night trip
Posted 1 month ago
Cozy cabin near Lewis and Clark Lake and CJ’s at the Lake

More cheap stays in Santee

Lewis and Clark Resort

Lewis and Clark Resort

43496 Shore Drive Yankton SD
AED 331
AED 349 total
8 Sep - 9 Sep
includes taxes & fees
9/10 Wonderful! (333 reviews)
Lewis and Clark Resort

Frequently asked questions

Where is the best place for a stay in Santee?
Lewis and Clark Resort, located 16.8 mi (27 km) from the heart of Santee, is a top choice for your stay based on our traveler data. Family, friendly country farm home. Enjoying peace and quiet. is another good choice for your stay in the area. See all available top hotels, or vacation rentals in Santee.
What are some of the best vacation rentals that Santee has to offer?
Newly Remodeled Creekside Bungalow on 3 acres with private Beach/Creek access: This vacation home rental near Santee is located in a rural location and offers a barbecue grill, air-conditioning, and WiFi to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Santee.
If I need to cancel my hotel reservation in Santee, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santee.
Where can I learn more about changing or cancelling my trip to Santee?
For more information about rescheduling or cancelling your trip to Santee, click here.
What is staying in Santee like?
Those traveling to Santee are sure to enjoy the sights to see and things to do. There are 66 hotels and other accommodations in the surrounding area. Find out more about Santee.
What are the top places to visit in Santee?
A favorite place to visit is Lewis and Clark Lake. You'll also find Niobrara State Park and Lewis and Clark Recreation Area in the area. Check out what more to see and do in Expedia's Santee guide.
What's the weather like in Santee?
The hottest months are usually July and August with an average temp of 72°F, while the coldest months are January and February with an average of 26°F. The snowiest months in Santee are January, December, October, and March, with each month seeing an average of 8 inches of snowfall.