A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

St. Charles Vacation Rentals

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Check prices for these dates

In two weeks
20 Nov - 22 Nov
In two months
1 Jan - 3 Jan
In three months
29 Jan - 31 Jan
In four months
26 Feb - 28 Feb

Our top choices for St. Charles vacation rentals

A cozy living room with a brick wall, a white sofa with colorful cushions, a small black table, and a potted plant.

1. Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (123 reviews)
"Great"
United States
Richard W.
The price is AED 357
AED 801 total
includes taxes & fees
9 Nov - 10 Nov
Prime Loft of Main Street
An outdoor hot tub area with seating and a covered patio.

2. Private Basement - Two King Beds and Hot Tub

Private Basement - Two King Beds and Hot Tub
Saint Charles
9.6 out of 10, Exceptional, (5 reviews)
"Clean. The patio was very comfortable and nice to sit and relax. The beds were also very comfortable."
United States
Beth S.
The price is AED 375
AED 1,082 total
includes taxes & fees
9 Nov - 10 Nov
Private Basement - Two King Beds and Hot Tub
A spacious living area with a wooden floor, a dining table with chairs, a flat-screen TV mounted on the wall, and a kitchen area with modern appliances.

3. The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (196 reviews)
"Very cute place, walking distance to everything."
United States
Liberty A.
The price is AED 408
AED 860 total
includes taxes & fees
9 Nov - 10 Nov
The Lofts of North Main Street
A staircase with white railings and a ceiling fan.

4. Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (72 reviews)
"This was a prime spot for downtown activities! Near everything and not far from STL. Would absolutely stay here again!"
United States
Rebecca F.
The price is AED 408
AED 860 total
includes taxes & fees
9 Nov - 10 Nov
Amazing Renovated Historic Loft on Main Street
A living room with a sofa, armchairs, a coffee table, a lamp, a ceiling fan, and a rug.

5. Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!
St. Charles Historic District
9.6 out of 10, Exceptional, (87 reviews)
"Quaint and quiet, with easy access to downtown St Charles."
United States
Jeffrey E.
The price is AED 437
AED 871 total
includes taxes & fees
9 Nov - 10 Nov
Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!
A neatly made bed with a stack of folded towels, a bedside lamp, and a ceiling fan in a room with a large window and a wall-mounted artwork.

6. Home Near Main with Pet-Friendly Yard and Office

Home Near Main with Pet-Friendly Yard and Office
St. Charles Historic District
10.0 out of 10, Exceptional, (13 reviews)
"Very close to downtown St. Charles and the Kati Trail. The home is cute and bed is comfortable. Easy check in process and fenced in back yard was nice to have."
United States
Jessica S.
The price is AED 420
AED 961 total
includes taxes & fees
10 Nov - 11 Nov
Home Near Main with Pet-Friendly Yard and Office
A modern apartment with a living room, kitchen, and dining area.

7. Adorable 2 King Bed Frenchtown Home

Adorable 2 King Bed Frenchtown Home
Saint Charles
10.0 out of 10, Exceptional, (5 reviews)
"Great location. Pet friendly. Perfect space for my wife and I to work remotely. So many great local places in close proximity. Host was quick to answer any and all questions. Would absolutely book again."
United States
Don S.
The price is AED 441
AED 1,135 total
includes taxes & fees
9 Nov - 10 Nov
Adorable 2 King Bed Frenchtown Home
A living room with a black leather sofa, two grey armchairs, a wooden coffee table, and a wall clock.

8. 6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
9.0 out of 10, Wonderful, (4 reviews)
"Excellent"
United States
Scott N.
The price is AED 364
AED 1,008 total
includes taxes & fees
9 Nov - 10 Nov
6th street 101 - Walk to Main St
A spacious living area with a grey sofa, a wooden coffee table, and a kitchen area with a bar stool seating.

9. Charming open 4bd and screen-in porch! Sleeps 10!

Charming open 4bd and screen-in porch! Sleeps 10!
Saint Charles
9.0 out of 10, Wonderful, (52 reviews)
"Great property, plenty of space, was very clean!"
United States
Will M.
The price is AED 739
AED 2,373 total
includes taxes & fees
9 Nov - 10 Nov
Charming open 4bd and screen-in porch! Sleeps 10!
A bar area with a wooden bar and two stools, a ceiling fan, and a window with blinds.

10. The Olive House - Near Main Street- Fully rehabbed

The Olive House - Near Main Street- Fully rehabbed
Saint Charles
8.6 out of 10, Excellent, (13 reviews)
"This was the perfect place to stay and the property was great"
United States
Stephen L.
The price is AED 459
AED 1,236 total
includes taxes & fees
9 Nov - 10 Nov
The Olive House - Near Main Street- Fully rehabbed
A modern living room with a sofa, coffee table, and armchair, a painting on the wall, and large windows with blinds.

11. Rustic Revival 2BR on Main with Free Parking

Rustic Revival 2BR on Main with Free Parking
St. Charles Historic District
9.6 out of 10, Exceptional, (9 reviews)
"We loved the vibe of this area. So much history and beauty. The property was clean. The beds were comfy and the bedding was so cozy as well. There is no oven or stove but has a hot plate and a microwave. The parking access was great as well. Smooth checking and great communication with host. 10/10 recommend this place. "
Canada
Amanda B.
The price is AED 480
AED 1,188 total
includes taxes & fees
10 Nov - 11 Nov
Rustic Revival 2BR on Main with Free Parking
A living room with a flat-screen TV, a sofa with patterned cushions, a coffee table, and a rug.

12. Cottage on Historic Main Street- Low Cleaning fee

Cottage on Historic Main Street- Low Cleaning fee
St. Charles Historic District
10.0 out of 10, Exceptional, (24 reviews)
"This was the perfect space for a quick trip! Extremely clean and in a great location, definitely would stay again!"
United States
Elizabeth D.
The price is AED 489
AED 1,100 total
includes taxes & fees
9 Nov - 10 Nov
Cottage on Historic Main Street- Low Cleaning fee
A hallway with a door, two potted plants, a doormat, and a view of a brick building through large windows.

13. Dog-Friendly 2BR Near Main Street

Dog-Friendly 2BR Near Main Street
Saint Charles
8.0 out of 10, Very good, (5 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
The price is AED 414
AED 1,081 total
includes taxes & fees
23 Nov - 24 Nov
Dog-Friendly 2BR Near Main Street
A living room with a gray sectional sofa, a wooden coffee table, and a patterned rug.

14. 5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1

5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1
St. Charles Historic District
8.8 out of 10, Excellent, (16 reviews)
"House was beautiful. Very nice quiet stay"
United States
Amy S.
The price is AED 364
AED 896 total
includes taxes & fees
9 Nov - 10 Nov
5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1
A modern kitchen with white cabinets, a built-in microwave, a stove, and a window providing natural light.

15. Pet-Friendly Duplex on Historic Main

Pet-Friendly Duplex on Historic Main
St. Charles Historic District
10.0 out of 10, Exceptional, (26 reviews)
"Great location"
United States
todd p.
The price is AED 444
AED 992 total
includes taxes & fees
10 Nov - 11 Nov
Pet-Friendly Duplex on Historic Main
A modern kitchen with white cabinets, a stainless steel refrigerator, and a central island with bar stools.

16. Stunning 1890's Home - Sleeps 8!

Stunning 1890's Home - Sleeps 8!
St. Charles Historic District
10.0 out of 10, Exceptional, (141 reviews)
"Super cute property, fantastic location. Very well maintained and clean, would definitely stay here again. "
United States
Jason T.
The price is AED 678
AED 1,425 total
includes taxes & fees
10 Nov - 11 Nov
Stunning 1890's Home - Sleeps 8!
A modern kitchen with stainless steel appliances, white cabinetry, and a brick accent wall.

17. Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (39 reviews)
"Lovely place to stay!"
United States
Margaret A.
The price is AED 456
AED 1,270 total
includes taxes & fees
10 Nov - 11 Nov
Historic Main St. Customs House Upstairs Apartment
A spacious living room with a green sofa, a purple armchair, a wooden staircase, and a ceiling fan.

18. St. Charles 1860's Gem - Sleeps 6!

St. Charles 1860's Gem - Sleeps 6!
St. Charles Historic District
9.8 out of 10, Exceptional, (171 reviews)
"Perfect home, fantastic stay. Thank you so much. We hope to visit again!"
United States
Jackie D.
The price is AED 580
AED 1,119 total
includes taxes & fees
15 Nov - 16 Nov
St. Charles 1860's Gem - Sleeps 6!
A modern living room with a spiral staircase, a brick wall, a dining area, and a gray sofa.

19. Historic Main Street 2BR Near Shops

Historic Main Street 2BR Near Shops
St. Charles Historic District
9.4 out of 10, Exceptional, (42 reviews)
"This property has a nice renovation while keeping a lot of its original character. Very clean and comfortable beds as well. The location couldn’t be better! We really enjoyed our stay."
United States
William O.
The price is AED 480
AED 1,477 total
includes taxes & fees
10 Nov - 11 Nov
Historic Main Street 2BR Near Shops
A two-story house with a front porch, a mailbox, and a number 815 sign.

20. HotTub-2br2b-near Historic Main Street

HotTub-2br2b-near Historic Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (28 reviews)
"Comfy beds, great location!"
United States
Jessie W.
The price is AED 585
AED 1,149 total
includes taxes & fees
12 Nov - 13 Nov
HotTub-2br2b-near Historic Main Street
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles Hotel Reviews

Moonrise Hotel

Moonrise Hotel

8/10 Good
"This was our 4th stay this year and while we would certainly stay again I was disappointed by the cleanliness of the room. The garbage had not been taken out and a towel from the previous guests was still in the bathroom."
Meaghan 1-night trip
Posted 10 hours ago
Moonrise Hotel

Frequently asked questions

Can I find vacation rentals in St. Charles?

Yes, you can find vacation rentals near popular attractions in St. Charles, or you can choose a secluded option if you're looking for relaxation. Tourists like the array of shops and top-notch restaurants in St. Charles. The live music and theater scene are some other things you might like to check out during your trip.

What are some of the best vacation rentals that St. Charles has to offer?

The St. Charles Guest House, lovely historic home, fun for families and groups: This St. Charles vacation home rental is located on a river and offers a fireplace, air-conditioning, and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Some other top choices in St. Charles are St. Charles 1860's Gem - Sleeps 6! and Honky Tonk Hideaway | 2BR Near Historic Main St.

How many vacation rentals are there in St. Charles?

Expedia has 88 vacation rentals for your stay in St. Charles.

What can I see and do in St. Charles?

Katy Trail and Mississippi River are a couple of scenic spots to enjoy the outdoors, whereas Missouri Artists on Main is one of the cultural attractions. Other places in town to visit include Historic Main Street and Lewis & Clark Boathouse and Nature Center.

What are vacation rentals like in St. Charles?

Vacation rentals are privately owned accommodations you can book for several days or more in St. Charles. Vacation rentals provide amenities such as laundry facilities and kitchens to help you enjoy your stay. If you're concerned about a clean environment, vacation rentals can offer a sense of privacy away from shared hotel elevators and lobbies packed with people while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which makes a vacation rental an attractive option for a family getaway.