Clayton, MO
St. Louis
Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's acclaimed art scene or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Gateway Arch
Find out about the history of Gateway Arch, one of the top monuments in St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
St. Louis Zoo
Why not visit the native and exotic animals who live at St. Louis Zoo during your trip to St. Louis? Amble around the area's lush forest or attend a sporting event.
City Museum
You can spend an afternoon studying the exhibits at City Museum during your trip to St. Louis. Experience the area's fascinating museums and great live music.
Forest Park
After visiting Forest Park, make a plan to see the other sights and activities in St. Louis. Discover the area's entertainment choices and shops.
Clayton Hotel Deals
Clayton Plaza Hotel & Extended Stay
All the employees were friendly and welcoming. The breakfast is amazing
Reviewed on 18 January 2026
The Ritz-Carlton, St. Louis
Very courteo
Reviewed on 13 January 2026
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
The breakfast was fresh. LOts of great options.. I do wish there were a few more meat choices and egg choices. BUt you have a great variety and very friendly kitchen help!! Also the bar had great Service and bartender was super nice.. A few more options and price lowered and it wouldve been perfect.. ...
Reviewed on 12 January 2026
AC Hotel St. Louis Clayton
My room was spotless and very well put together.
Reviewed on 9 January 2026
21C Museum Hotel St Louis
Great hotel! Art, food and drinks were fantastic
Reviewed on 18 January 2026
Hyatt Regency St. Louis at The Arch
Very clean rooms the staff was excellent and ver helpful and friendly. Being so close to the arch was wonderful for views at night 100/10 recommend
Reviewed on 20 January 2026
Other neighborhoods around Clayton
University City
Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.
Dogtown
If you're looking for some top things to see and do in Dogtown and surrounding area, you can visit St. Louis Zoo and St. Louis Art Museum.
Ladue
The restaurants and churches are a few reasons travelers visit Ladue. Though there aren't many top sights in the neighborhood, you can visit Saint Louis Galleria Mall and St. Louis Art Museum, a few notable attractions nearby.
The Hill
If you're looking for some top things to see and do in The Hill and surrounding area, you can visit St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
The Grove
The Grove might not have many top sights, but St. Louis Science Center and Missouri Botanical Gardens and Arboretum are two attractions nearby that you can check out.
Clayton, MO
- Places of interest
- Clayton Hotels by Star Rating
- More Hotel Options in Clayton
- Hotels in top St. Louis neighborhoods
- Clayton Hotels by Brand
- Chapel of St. Timothy And St. Titus
- St. Louis Union Station
- Busch Stadium
- Gateway Arch
- St. Louis Zoo
- Washington University in St. Louis
- Enterprise Center
- Barnes Jewish Hospital
- America's Center Convention Complex
- Dome at America’s Center
- City Museum
- Forest Park
- Ameristar Casino St. Charles
- St. Louis University
- Mississippi River
- Hollywood Casino Amphitheatre
- Fox Theater
- Westport Plaza
- St Charles Convention Center
- Horseshoe St. Louis Casino
- Anheuser-Busch Brewery
- Magic House - St. Louis Children's Museum
- Missouri Botanical Gardens and Arboretum
- Hidden Valley Ski Resort
- Grant's Farm
- St. Louis Children's Hospital
- Saint Louis Galleria Mall
- St. Louis Aquarium at Union Station
- Route 66 State Park
- Lindenwood University
- Show Me
- St. Louis Science Center
More Hotel Options in Clayton
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- Luxury Hotels in Clayton
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- Resorts & Hotels with Spas in Clayton
- Romantic Hotels in Clayton
- Shopping Hotels in Clayton
