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Holiday Inn Express & Suites St. Louis South - I-55 by IHG

2.5 star property
Hotel in St. Louis with free breakfast and a 24-hour fitness center

Choose dates to view prices

Located in the business district, Holiday Inn Express & Suites St. Louis South - I-55 offers practical comforts for busy travelers. Enjoy a hearty breakfast buffet, reliable in-room WiFi, an indoor pool for relaxation, and a 24-hour gym.

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Pool
  • Housekeeping
  • 24/7 front desk
  • Air conditioning
The current price is AED 433
AED 498 total
includes taxes & fees
9 Nov - 10 Nov

Room options

Available filters for rooms
Showing 10 of 10 rooms

View all photos for Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

Room amenity

Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

9.4 out of 10
Exceptional
(13 reviews)

Highlights

Air conditioning
Heating
Connecting rooms available
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
Shower/tub combination
  • 28 sq m
  • Sleeps 4
  • 2 Queen Beds

View all photos for Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

Standard Room, 2 Queen Beds, Accessible (Mobil Tub) | In-room safe, desk, laptop workspace, blackout drapes

Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

9.6 out of 10
Exceptional
(4 reviews)

Highlights

Air conditioning
Heating
Connecting rooms available
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
Hair dryer
  • 28 sq m
  • Sleeps 4
  • 2 Queen Beds

View all photos for Suite, 1 Bedroom (2 Queen, Extra Living Area)

Room amenity

Suite, 1 Bedroom (2 Queen, Extra Living Area)

9.4 out of 10
Exceptional
(26 reviews)

Highlights

Air conditioning
Heating
Connecting rooms available
Free rollaway/extra beds
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
  • 28 sq m
  • Sleeps 6
  • 2 Queen Beds

View all photos for Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

Room amenity

Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

9.0 out of 10
Wonderful
(7 reviews)

Highlights

Air conditioning
Heating
Connecting rooms available
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
Shower/tub combination
  • 28 sq m
  • Sleeps 4
  • 1 King Bed

View all photos for Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

Free toiletries, hair dryer, towels, soap

Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

10.0 out of 10
Exceptional
(1 review)

Highlights

Air conditioning
Heating
Connecting rooms available
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
Shower/tub combination
  • 28 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (Extra Living, Walk in Shwr)

Suite, 1 King Bed (Extra Living, Walk in Shwr) | In-room safe, desk, laptop workspace, blackout drapes

Suite, 1 King Bed (Extra Living, Walk in Shwr)

9.0 out of 10
Wonderful
(4 reviews)

Highlights

Air conditioning
Heating
Connecting rooms available
Free rollaway/extra beds
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
  • 28 sq m
  • Sleeps 4
  • 1 King Bed

View all photos for Standard Room, 1 King Bed (Bath Shwr Combo)

Room amenity

Standard Room, 1 King Bed (Bath Shwr Combo)

9.8 out of 10
Exceptional
(14 reviews)

Highlights

Air conditioning
Heating
Connecting rooms available
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
Shower/tub combination
  • 28 sq m
  • Sleeps 4
  • 1 King Bed

View all photos for Standard Room

Standard Room | In-room safe, desk, laptop workspace, blackout drapes

Standard Room

Highlights

Air conditioning
Heating
Connecting rooms available
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
Shower/tub combination
  • 28 sq m
  • Sleeps 2
  • 1 Twin Bed

View all photos for Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living) | In-room safe, desk, laptop workspace, blackout drapes

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

Highlights

Air conditioning
Heating
Connecting rooms available
Free rollaway/extra beds
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
  • 28 sq m
  • Sleeps 4
  • 1 King Bed

View all photos for Standard Room, 2 Queen Beds

Room amenity

Standard Room, 2 Queen Beds

9.4 out of 10
Exceptional
(72 reviews)

Highlights

Air conditioning
Heating
Connecting rooms available
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
Shower/tub combination
  • 28 sq m
  • Sleeps 4
  • 2 Queen Beds

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  • Pet friendly
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includes taxes & fees
23 Nov - 24 Nov
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About the neighborhood

Map
4250 Midamerica Lane, St. Louis, MO, 63129

What's nearby

  • Barnes Jewish South Campus - 5 min walk - 0.4 km
  • Mercy Hospital South - 4 min drive - 7.3 km
  • River City Casino - 10 min drive - 12.8 km
  • Magic House - St. Louis Children's Museum - 12 min drive - 17.5 km
  • Grant's Farm - 13 min drive - 15.6 km

Getting around

  • Kirkwood Station - 17 min drive
  • St. Louis Lambert Intl. Airport (STL) - 32 min drive

Restaurants

  • ‪Burger King - ‬10 min walk
  • ‪Popeyes Louisiana Kitchen - ‬4 min walk
  • ‪Starbucks - ‬9 min walk
  • ‪Rich & Charlie's Italian Restaurant - ‬3 min drive
  • ‪Hardee's / Red Burrito - ‬11 min walk

About this property

Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Hotel in the business district
A free breakfast buffet, a 24-hour gym, and a business center are just a few of the amenities provided at Holiday Inn Express & Suites St. Louis South - I-55 by IHG. Stay connected with free in-room WiFi.
You'll also enjoy perks such as:
  • An indoor pool along with sun loungers
  • Free self parking
  • A 24-hour front desk, meeting rooms, and an elevator
  • A front-desk safe, a vending machine, and smoke-free premises
  • Guest reviews say great things about the breakfast and helpful staff
Room features
All 99 rooms offer comforts such as laptop-friendly workspaces and air conditioning, as well as thoughtful touches like free WiFi and safes. Guest reviews highly rate the clean rooms at the property.
More amenities include:
  • Bathrooms with free toiletries and hair dryers
  • 49-inch flat-screen TVs with cable channels
  • Wardrobes/closets, refrigerators, and microwaves

Similar properties

Exterior

Fairfield Inn & Suites by Marriott St. Louis South

  • Pool
  • Breakfast included
  • Parking included
  • Free WiFi
9.6 out of 10, Exceptional, 317 reviews
The price is AED 426
AED 490 total
includes taxes & fees
23 Nov - 24 Nov
Fairfield Inn & Suites by Marriott St. Louis South

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 9:30 AM

Things to do

  • 24-hour gym
  • Indoor pool

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • Indoor pool

Conveniences

  • 24-hour front desk
  • Safe at front desk
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Housekeeping (daily)

Business services

  • Business center
  • Meeting rooms

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Stair-free path to entrance
  • Visual alarms in hallways
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible van parking

More

  • 4 floors
  • At least 10% of profits reinvested in community and sustainability
  • Banquet hall
  • No plastic drinking straws
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 49-inch flat-screen TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: 2:30 AM
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets not allowed (service animals are welcome, and are exempt from fees)

Children and extra beds

Children are welcome
Free cribs are available on request at the property

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)

We should mention

Pool access available from 8 AM to 10 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Holiday Inn Express St. Louis South I-55 Hotel
Holiday Inn Express St. Louis South I-55
Inn Express St Louis I55
Holiday Inn Express Suites St. Louis South I 55
Holiday Inn Express Suites St. Louis South I 55 by IHG
Holiday Inn Express Suites St. Louis South I 55 an IHG Hotel
Holiday Inn Express & Suites St. Louis South - I-55 by IHG Hotel

Frequently asked questions

Does Holiday Inn Express & Suites St. Louis South - I-55 by IHG have a pool?

Yes, this property has an indoor pool. Pool access is from 8 AM–10 PM.

How much does it cost to stay at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

As of 5 November 2025, prices found for a 1-night stay for 2 adults at Holiday Inn Express & Suites St. Louis South - I-55 by IHG on 9 November 2025 start from $135.69, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is Holiday Inn Express & Suites St. Louis South - I-55 by IHG pet-friendly?

No, only service animals are welcome at the property.

How much is parking at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Self parking is free at this property.

What time is check-in at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Check-in start time: 3:00 PM; Check-in end time: 2:30 AM.

What time is check-out at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Check-out is at 11 AM.

Where is Holiday Inn Express & Suites St. Louis South - I-55 by IHG located?

Situated in the business district, this hotel is 0.3 mi (0.6 km) from Barnes Jewish South Campus and within 3 mi (5 km) of St Anthony's and Suson Park. Meramec River and Mercy Hospital South are also within 6 mi (10 km).

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