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Compare Seneca 3 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Clemson University's James F. Martin Inn
Clemson University's James F. Martin Inn
9.6 out of 10, Exceptional, (929)
The price is AED 547
AED 607 total
includes taxes & fees
3 Sep - 4 Sep

The Inn at Patrick Square
The Inn at Patrick Square
9.8 out of 10, Exceptional, (749)
The price is AED 584
AED 648 total
includes taxes & fees
3 Sep - 4 Sep

Days Inn by Wyndham Clemson
Days Inn by Wyndham Clemson
7.0 out of 10, Good, (184)
The price is AED 291
AED 323 total
includes taxes & fees
8 Sep - 9 Sep

Holiday Inn Anderson by IHG
Holiday Inn Anderson by IHG
8.8 out of 10, Excellent, (675)
The price is AED 400
AED 444 total
includes taxes & fees
10 Sep - 11 Sep

Hilton Garden Inn Anderson
Hilton Garden Inn Anderson
9.0 out of 10, Wonderful, (641)
The price is AED 343
AED 381 total
includes taxes & fees
14 Sep - 15 Sep

Home2 Suites by Hilton Anderson Downtown
Home2 Suites by Hilton Anderson Downtown
9.2 out of 10, Wonderful, (192)
The price is AED 526
AED 583 total
includes taxes & fees
14 Sep - 15 Sep

Courtyard Marriott Clemson
Courtyard Marriott Clemson
9.0 out of 10, Wonderful, (510)
The price is AED 526
AED 583 total
includes taxes & fees
14 Sep - 15 Sep

Residence Inn by Marriott Anderson Clemson
Residence Inn by Marriott Anderson Clemson
9.6 out of 10, Exceptional, (82)
The price is AED 525
AED 583 total
includes taxes & fees
14 Sep - 15 Sep
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Learn more about Seneca
Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

Photo by Cindy Keese
Open Photo by Cindy Keese
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Explore more hotels
- Fall fun at the cabin! Convenient to Lake Keowee and Clemson
- 6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.
- Charming 3-bedroom house with WiFi and AC in serene Seneca on Lake Hartwell
- New to VRBO! Big water views, private dock, pool table, 15 min Clemson!
- Fabulous Tiny House with AC in charming Seneca
- Incredible 10 BR home with pool
- 5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!
- Days Inn by Wyndham Anderson
- Best Western Plus Clemson Hotel & Conference Center
- Comfort Inn & Suites Clemson - University Area
- The Shepherd Hotel Downtown Clemson
- Inn @ Clemson
- Wooded Cottage - 3 Mi to Clemson University
- Horizon Inn & Suites
- Hampton Inn Clemson-University Area
- Quality Inn Clemson near University
- Clemson University's James F. Martin Inn
- Days Inn by Wyndham Easley/Greenville/Clemson Area
- Baymont by Wyndham Easley/Greenville
- Holiday Inn Express & Suites Clemson by IHG