Find 4 Star Hotels in Florida Keys from AED 1,213

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Florida Keys 4 Star Hotels

Our top choices for Florida Keys 4-star hotels

Reefhouse Resort & Marina

Reefhouse Resort & Marina
4.5 star property
Key Largo
9.2 out of 10, Wonderful, (1,388 reviews)
"Clean rooms, nice staff, great beach area."
United States
Brittany
The price is AED 1,392
AED 1,713 total
includes taxes & fees
12 Apr - 13 Apr
Reefhouse Resort & Marina

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
Key Largo
8.6 out of 10, Excellent, (1,009 reviews)
"Great resort. Very pretty beach."
United States
Borsu Valente
The price is AED 1,596
AED 1,998 total
includes taxes & fees
13 Apr - 14 Apr
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Amara Cay Resort

Amara Cay Resort
4.0 star property
Matecumbe
8.8 out of 10, Excellent, (1,257 reviews)
"Loved the resort, we actually arrived a little earlier than the check in time but we were able to enjoy the amenities. Took the bikes for a little ride around, hang out by the pool and grab some nachos at the bar (amazing) definitely will come back on my next visit."
United States
Leibeth
The price is AED 897
AED 1,278 total
includes taxes & fees
26 Mar - 27 Mar
Amara Cay Resort

Hawks Cay Resort

Hawks Cay Resort
4.0 star property
Marathon
8.0 out of 10, Very Good, (1,009 reviews)
"Beautiful property with amazing pools. Restaurants were fabulous. Would definitely stay again. "
United States
Lisa
The price is AED 1,433
AED 1,869 total
includes taxes & fees
12 Apr - 13 Apr
Hawks Cay Resort

Islander Resort

Islander Resort
4.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,007 reviews)
"Wonderful stay. Staff, rooms, grounds, food were all excellent."
United States
Kim
The price is AED 1,367
AED 1,785 total
includes taxes & fees
12 Apr - 13 Apr
Islander Resort

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
8.8 out of 10, Excellent, (1,005 reviews)
"Room was spacious. "
United States
Christia
The price is AED 1,466
AED 1,851 total
includes taxes & fees
12 Apr - 13 Apr
Playa Largo Resort & Spa, Autograph Collection

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
4.0 star property
Islamorada
9.0 out of 10, Wonderful, (170 reviews)
"Spotless room, friendly staff, excellent food"
United States
Denise
The price is AED 1,058
AED 1,434 total
includes taxes & fees
15 Apr - 16 Apr
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

La Siesta Resort & Villas

La Siesta Resort & Villas
4.0 star property
Matecumbe
8.8 out of 10, Excellent, (1,001 reviews)
"Grrat view from room and location is awesome."
United States
Cheryl
The price is AED 839
AED 1,213 total
includes taxes & fees
25 Mar - 26 Mar
La Siesta Resort & Villas

Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
4.0 star property
Marathon
8.8 out of 10, Excellent, (1,005 reviews)
"Everything was great"
United States
Peter
The price is AED 1,386
AED 1,802 total
includes taxes & fees
12 Apr - 13 Apr
Tranquility Bay Beachfront Hotel and Resort

Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
4.0 star property
Marathon
8.2 out of 10, Very Good, (178 reviews)
"Property was clean and staff were helpful. Would stay again."
United States
Douglas Fredrick
The price is AED 3,522
AED 4,190 total
includes taxes & fees
26 Mar - 27 Mar
Villas At Hawks Cay Resort

Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
4.0 star property
Marathon
9.4 out of 10, Exceptional, (418 reviews)
"Every single part of our stay at Grassy Flats was 5/5! Staff, room, ocean view, pool, dining, market, beach, etc. highly recommend!"
Canada
KAREN
The price is AED 1,157
AED 1,478 total
includes taxes & fees
14 Apr - 15 Apr
Grassy Flats Resort & Beach Club

The Islands of Islamorada

The Islands of Islamorada
4.0 star property
Matecumbe
9.8 out of 10, Exceptional, (72 reviews)
"Beautiful accommodations and location, very clean, many activities available at resort"
United States
Janet
The price is AED 2,567
AED 3,091 total
includes taxes & fees
13 Apr - 14 Apr
The Islands of Islamorada

The Reef at Marathon, Florida Keys

The Reef at Marathon, Florida Keys
4.0 star property
Marathon
9.0 out of 10, Wonderful, (14 reviews)
"We enjoyed the pool, canoe, parking right near the unit. Clean, had everything you needed. Centrally located in the middle of the keys. "
United States
Linda L
The Reef at Marathon, Florida Keys

Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
4.0 star property
Marathon
10.0 out of 10, Exceptional, (2 reviews)
"Wonderful vacation!"
United States
Chardell
Marlin Bay Resort & Marina

Waterfront Luxury Villa

Waterfront Luxury Villa
4.0 star property
Marathon Shores
Waterfront Luxury Villa

The Caribbean Resort Coconut Palm North

The Caribbean Resort Coconut Palm North
4.0 star property
Matecumbe
The Caribbean Resort Coconut Palm North
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Florida Keys.
Still don't see what you're looking for?
See all properties in Florida Keys.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colorful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

Higgs Beach showing a sandy beach and tropical scenes as well as a large group of people

Top Florida Keys Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
If your Florida Keys adventure is in Key Largo, stay at Playa Largo Resort & Spa, Autograph Collection. With lots of amenities such as a firepit and a pillowtop mattress, it earns top marks from many Expedia travelers. Another sought-after option here is Bakers Cay Resort Key Largo, Curio Collection by Hilton. It's also rated 4 stars and features a steam room and a swimming pool.
How much does it cost to stay in a 4-star hotel in Florida Keys?
To find a 4-star hotel in Florida Keys that fits your budget, take advantage of Expedia's handy search filters. Take a look at the availability during your vacation dates and use our pricing filter to set your maximum rate. You can also sort your results by the most affordable retreat first.

  • Search for the lowest price from AED 1,531

What's the difference between 5-star and 4-star hotels in Florida Keys?
Offering a welcoming traveler experience and upmarket décor, 4-star hotels are an excellent option for your Florida Keys getaway. These types of accommodations generally feature loads of useful amenities that make it easy to unpack and relax — think pillowtop mattresses, pools and restaurants. Or live the high life at a 5-star hotel designed to spoil you with high-end perks and amenities. Concierge assistance, premium toiletries and fine dining are typically included at these deluxe properties.

Explore a world of travel with Expedia