Find 4 Star Hotels in Murphysboro, IL from AED 477
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Murphysboro 4 Star Hotels
Compare Murphysboro 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Walker's Bluff Casino Resort
Walker's Bluff Casino Resort
9.4 out of 10, Exceptional, (338)
The price is AED 477
AED 530 total
includes taxes & fees
8 Jun - 9 Jun

Davie School Inn
Davie School Inn
10.0 out of 10, Exceptional, (48)
The price is AED 573
AED 636 total
includes taxes & fees
8 Jun - 9 Jun
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Murphysboro
Escape to Murphysboro! Enjoy its fishing, food, and golf.

Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Murphysboro Hotels by Star Rating
Stay near popular Murphysboro attractions
- Hotels near Lake Murphysboro State Park
- Hotels near Hickory Ridge Public Golf Center
- Hotels near General John A. Logan Museum
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Southern Illinois University
- Hotels near Lake of Egypt
- Hotels near Giant City State Park
- Hotels near DuQuoin State Fairgrounds
- Hotels near I-57 Drag Strip
- Hotels near Marion Cultural and Civic Center
- Hotels near Blue Sky Vineyards
- Hotels near John A. Logan College
- Hotels near Stone Creek Golf Club and Resort
More Hotel Options in Murphysboro
More Accommodation Types in Murphysboro
- Vacation Homes in Murphysboro
- Cabin Rentals in Murphysboro
- Apartments in Murphysboro
- Motels in Murphysboro
- Cottages in Murphysboro
- RV Parks in Murphysboro
- B&B in Murphysboro
- Lodges in Murphysboro
- Farmstay in Murphysboro
- Condo Rentals in Murphysboro
- Guest Houses in Murphysboro
- Resorts in Murphysboro
- Villas in Murphysboro
Explore more hotels
- Motel 6 Marion, IL
- Comfort Inn & Suites Marion I-57
- Holiday Inn Express Hotel & Suites Marion Northeast by IHG
- Country Inn & Suites by Radisson, Marion, IL
- Home2 Suites by Hilton Carbondale
- Econo Lodge
- Quality Inn And Suites
- University Inn of Carbondale
- Hotel 7 Inn Anna
- Americas Best Value Inn Marion, IL
- Hampton Inn Carbondale
- Beautiful location in the secluded woods
- Americas Best Value Inn West Frankfort
- New cabin in the woods with private hot tub
- Laketree Inn And Suites Marion
- Quality Inn Carbondale University area
- Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
- Stones Throw from Giant City Park, Wineries, Hiking, Biking, Hunting and more.
- Rest, Relax and Renew. Our log cabin experience awaits your arrival.
- Secluded Rental Cabin on Southern Illinois Wine Trail, Private Hot Tub