Find 4 Star Hotels in Murphysboro, IL from AED122
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Murphysboro Hotels by Star Rating
Stay near popular Murphysboro attractions
- Lake Murphysboro State Park
- Hickory Ridge Public Golf Center
- General John A. Logan Museum
- Shawnee National Forest
- Mississippi River
- Southern Illinois University
- Lake of Egypt
- Giant City State Park
- DuQuoin State Fairgrounds
- I-57 Drag Strip
- Blue Sky Vineyards
- Marion Cultural and Civic Center
- Trail of Tears State Park
- John A. Logan College
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- Vacation Homes in Murphysboro (82)
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- Apartments in Murphysboro (19)
- Cottages in Murphysboro (14)
- Motels in Murphysboro (10)
- B&B in Murphysboro (4)
- Farmstay in Murphysboro (3)
- Condo Rentals in Murphysboro (2)
- Lodges in Murphysboro (2)
- Guest Houses in Murphysboro (1)
- Resorts in Murphysboro (1)
- Villas in Murphysboro (1)
Explore more hotels
- Quality Inn Carbondale University area
- Holiday Inn Carbondale-Conference Center, an IHG Hotel
- Super 8 by Wyndham Marion
- Motel 6 Marion, IL
- Hotel 7 Inn Anna
- Hampton Inn Carbondale
- Holiday Inn Express Hotel & Suites Marion Northeast, an IHG Hotel
- Americas Best Value Inn & Suites Pinckneyville
- Fairgrounds Inn
- Country Inn & Suites by Radisson, Marion, IL
- New cabin in the woods with private hot tub
- Rest, Relax and Renew. Our log cabin experience awaits your arrival.
- Econo Lodge
- Americas Best Value Inn West Frankfort
- Wine Country Farmhouse On the Wine 🍷 Trail! Private Lake kayaks Fire Pit 🔥
- Super 8 by Wyndham Du Quoin
- Feels like your in a Tree House!On the Wine 🍷Trail! Fire🔥Pit Private Location
- Americas Best Value Inn Marion, IL
- Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
- University Inn of Carbondale