Photo by Cindy Keese

Find 4 Star Hotels in Seneca, SC from AED 272

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Compare Seneca 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (647)
"This was a phenomenal place to stay in downtown Clemson. We will definitely be back! "
The price is AED 657
AED 730 total
includes taxes & fees
1 Sep - 2 Sep
The Shepherd Hotel Downtown Clemson

The Abernathy of Clemson

4.0 star property
9.6 out of 10, Exceptional, (536)
"Big rooms, convenient parking, quiet. I would stay again in a heartbeat! "
The Abernathy of Clemson

Liberty Hall Bed and Breakfast

4.0 star property
10.0 out of 10, Exceptional, (67)
"In town for a recent college visit. Great location in a stunning historic BNB. Breakfast was wonderful and customer service was exceptional. Would absolutely recommend staying here and plan to stay again."
The price is AED 394
AED 621 total
includes taxes & fees
7 Aug - 8 Aug
Liberty Hall Bed and Breakfast

Southern Sunshine Retreat

4.0 star property
Southern Sunshine Retreat

Lake Hartwell Frank Howard Home Clemson

4.0 star property
The price is AED 272
AED 1,465 total
includes taxes & fees
4 Aug - 5 Aug
Lake Hartwell Frank Howard Home Clemson

Belvedere

4.0 star property
8.0 out of 10, Very Good, (1)
"Bring everything. Including hangers for your clothes, salt and pepper, etc. it is like staying at a place that has one purpose, to rent out. Beds are uncomfortable. Nice big closets with one wire hanger. Why??? "
Belvedere

228 Lakeland

4.0 star property
228 Lakeland

Pendleton

4.0 star property
Pendleton
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Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

View from the dike in Clemson, SC. This trail is used by runners, bikers, and lots of dog walkers.
Photo by Cindy Keese
Open Photo by Cindy Keese

Top Seneca Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Seneca?
To book a 4-star hotel in Seneca that fits your budget, use Expedia's handy search filters. Check out the available options during your vacation dates and use our pricing filter to set your maximum rate. You can also sort your results by the most wallet-friendly stay first.

  • Search for the lowest price from AED 272

What's the difference between 5-star and 4-star hotels in Seneca?
If you decide to vacation at a 4-star hotel in Seneca, you'll usually find lots of amenities to make sure you're relaxed, such as a gym, pool and restaurant. You can look forward to excellent service and deluxe accommodations. Choose a 5-star hotel and you'll get a few extra perks — think around-the-clock concierge, on-site spas and opulent turndown services. You'll most likely get additional amenities and first-class services at a 5-star stay, but both are fabulous options for luxury guests.
Does Seneca have any 4-star all-inclusive resorts?
Finding your dream resort in Seneca is as simple as entering your dates and destination, and selecting our "All inclusive" filter. Stay and play where everything is already taken care of like your accommodations, food, activities and entertainment, or go for a standard 4-star resort in or around this much-loved destination.