Find 4 Star Hotels in Southeast Missouri, MO

To book a 4-star hotel in Southeast Missouri that matches your budget, take advantage of Expedia’s handy search filters. Browse the available options during your chosen dates and use our pricing filter to set your limit. You can also list your results by the cheapest stay first.

• Search for the lowest price

Treat yourself to refined living during your Southeast Missouri vacation by choosing a 4-star hotel. As well as featuring upmarket surroundings, these retreats are typically packed with amenities, including complimentary bathrobes, large beds and more. A 5-star hotel will go above and beyond to make your trip an even more lavish and memorable one. 24-hour front desk, on-site spas and gourmet dining are a few of the superior services and conveniences you’ll likely have access to.

Use our “All inclusive” filter to find your next escape in Southeast Missouri where just about everything is taken care of, from your accommodations to your food, entertainment and activities. We can also help you find standard 4-star stays in and around this sought-after destination.

You’ll feel at home at Urban Lofts in Perryville, Southeast Missouri. Our 4-star apartments offer the freedom and convenience to fully immerse yourself in the local atmosphere, while ensuring you have all the necessary comforts for an unforgettable stay.