A red truck parked near a tent in a desert at night with stars visible in the sky.

Find 5 Star Hotels in Eastern Oregon, OR

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Eastern Oregon 5 Star Hotels

Tonight
14 Oct - 15 Oct
Tomorrow
15 Oct - 16 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Eastern Oregon

Casinos, a scenic riverfront, and sights from Anthony Lakes Ski Area to Crystal Crane Hot Springs—discover it all in Eastern Oregon.

See all hotels in Eastern Oregon
A road with cattle on the side, surrounded by dry grassland and hills in the distance.
Photo by Rachel Samanyi

Top Eastern Oregon Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Eastern Oregon?
There are various pricing options for a 5-star hotel in Eastern Oregon on Expedia. The amount you pay will depend on your travel dates, trip length and other factors. Compare all of the available accommodations for your preferred dates and make use of our pricing and other filters to score the perfect high-end stay.
  • Search for the lowest price per night
What makes a hotel 5 stars in Eastern Oregon?
From gourmet dining venues and all-day gyms to swimming pools and dreamy bedding, the 5-star experience in Eastern Oregon is all about indulgence and comfort. But it requires more than just upscale amenities to receive a 5-star rating. Accommodations also have to deliver outstanding guest-focused services like in-room massages, on-site laundry and dry cleaning and room service any time night or day.
Are there any 5-star all-inclusive resorts in Eastern Oregon?
Find an upscale retreat that includes your lodging, food, activities and entertainment in Eastern Oregon with our handy filters. Search for properties rated 5 stars and select the "All inclusive" filter. Double-check what's included in the purchase price. That way, you can take full advantage of the premium perks on offer from the moment you get there.

Explore a world of travel with Expedia