Are there any 5-star all-inclusive resorts in Ladys Island?

Our convenient filters are the quickest way to search for exactly what you're looking for. Check the "All inclusive" and "5-star" boxes to show the most luxurious properties in Ladys Island where your meals, room, activities and entertainment are included in the upfront price. At these getaways, your trip is pure leisure from the moment you enter the lobby.

What are the top 5-star spa hotels in Ladys Island?

One of the best spa accommodations around Ladys Island, Anchorage 1770 is where you can escape the worries of everyday life. Select this 5-star stay and indulge in a variety of activities and treatments that are aimed at enhancing your overall health and well-being.

Are there any 5-star vacation rentals in Ladys Island?

You won't find any 5-star vacation rentals in Ladys Island on our site, but there are a range of other highly rated options worth looking into. Browse our vacation rentals in Ladys Island to find the best place for your stay.

The Best 5 Star Hotels in Ladys Island, SC from AED 589

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Our top choices for Ladys Island 5-star hotels

Montage Palmetto Bluff

Palmetto Bluff

Christine

AED 1,960 total

includes taxes & fees

4 Feb - 5 Feb

Anchorage 1770

Downtown Beaufort

Carla

Montage Palmetto Bluff Residences

Palmetto Bluff

"This was our second visit to Montage Palmetto Bluff and once again it did not disappoint. The hospitality we find here is second to none. Everywhere we went we were greeted with smiling faces. We’d like to give a special shout out to Carmela at the concierge desk who was so incredibly wonderful with our 4 year-old son, Henry. Everything she did and every recommendation she provided enhanced our stay. The natural beauty of this place is beyond compare. We cannot wait to visit again. "

Ashley

AED 6,267 total

includes taxes & fees

16 Feb - 17 Feb

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Ladys Island.

Hilton Beachfront Resort & Spa Hilton Head Island

1 Hotel Circle Hilton Head Island SC

AED 509

AED 700 total

25 Jan - 26 Jan

includes taxes & fees

8.4/10 Very Good! (1,405 reviews)

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Ladys Island

Venture to sights like Coosaw Island and Cat Island Driving Range as you discover Ladys Island.

See all hotels in Ladys Island