A coastal town with terracotta-roofed houses, a beach, and a castle on a hill.

Find 5 Star Hotels in Mytilene from AED 363

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Check availability on Mytilene 5 Star Hotels

Tonight
30 Sep - 1 Oct
Tomorrow
1 Oct - 2 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for Mytilene 5-star hotels

A resort with a pool, outdoor seating, and a view of the sea at dusk.
A spacious living room with a large window, a sofa, a coffee table, and a dining area with chairs and a table.
A dining area with a table and chairs, a vase with a flower, and a view of the sea through large windows.
A modern hotel room with a large bed, a desk, and a view of the ocean.

1. Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat
Lesvos
United States
Jack
AED 341
AED 437 total
includes taxes & fees
2 Oct - 3 Oct
Mythical Coast Wellness Retreat
A person standing on a balcony overlooking a pool and a modern building with a clear view of the sea.
A modern bar area with seating and a bar counter.
A modern hotel with a swimming pool, outdoor seating, and a view of the sea.
A hotel room with a bed, a desk, a TV, and a window with a view of buildings.

2. Elysion Hotel

Elysion Hotel
Lesvos
Turkey
ANINDYA
AED 408
AED 614 total
includes taxes & fees
15 Oct - 16 Oct
Elysion Hotel
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mytilene.
Loriet Hotel

Loriet Hotel

Vareia, Mitilene Lesvos Lesvos Island
AED 325
AED 398 total
7 Oct - 8 Oct
includes taxes & fees
8.4/10 Very Good! (92 reviews)
Loriet Hotel
Heliotrope Hotels

Heliotrope Hotels

Varia Lesvos Lesvos Island
AED 294
AED 363 total
2 Oct - 3 Oct
includes taxes & fees
Heliotrope Hotels
Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel

7, Skra str, Hatzidimitriou Park Lesvos
AED 458
AED 544 total
4 Oct - 5 Oct
includes taxes & fees
9.6/10 Exceptional! (172 reviews)
Theofilos Paradise Boutique Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Mytilene

The harbor city's neoclassical mansions and Byzantine castle offer glimpses into its rich past as a trading center. Explore the Archaeological Museum's ancient artifacts, then enjoy fresh seafood at tavernas along the waterfront promenade.

See all hotels in Mytilene
A coastal town with terracotta-roofed houses, a beach, and a castle on a hill.

Top Mytilene Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Mytilene?
You can find a range of pricing options for 5-star hotels in Mytilene on Expedia. How much you'll pay will depend on when you plan to travel, length of stay and other factors. Compare all of the available properties for your preferred dates and use our pricing and other filters to lock in the ideal high-end stay.
  • Search for the lowest price per night from AED 363
What makes a hotel 5 stars in Mytilene?
From high-end dining venues and fitness centers to pools and dreamy bedding, the 5-star experience in Mytilene is all about comfort and indulgence. But it calls for more than just top-notch amenities to receive a 5-star rating. Stays must also deliver remarkable guest-focused services like massage treatments, laundry and dry cleaning and room service any time night or day.
Are there any 5-star all-inclusive resorts in Mytilene?
Our handy filters are the quickest way to narrow down what you're looking for. Check the "All inclusive" and "5-star" boxes to show the most luxurious hotels in Mytilene where your lodging, meals, entertainment and activities are included in the price. At these stays, your trip is pure leisure from the moment you check in.

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