Find 5 Star Hotels in Port Isabel, TX from AED 282

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Check availability on Port Isabel 5 Star Hotels

Our top choices for Port Isabel 5-star hotels

Family House, 5 Bedrooms, Private Pool, Bay View | 5 bedrooms, Egyptian cotton sheets, premium bedding
Spacious Bay

Spacious Bay

Spacious Bay
5.0 star property
Port Isabel
Spacious Bay
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Port Isabel.
Margaritaville Beach Resort South Padre Island

Margaritaville Beach Resort South Padre Island

310 Padre Blvd South Padre Island TX
The price is AED 213 per night from Jan 4 to Jan 5
AED 213
AED 282 total
4 Jan - 5 January 2026
includes taxes & fees
8.6/10 Excellent! (1,899 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Port Isabel

Climb the historic lighthouse for sweeping views of South Padre Island and spot dolphins playing in the turquoise waters. Explore the treasures at Pirates Landing pier, where fishing adventures and fresh seafood restaurants create the perfect coastal getaway.

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Port Isabel

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Frequently asked questions

How much does it cost to stay in a 5-star hotel in Port Isabel?
You can find several pricing options for 5-star hotels in Port Isabel on Expedia. How much you'll pay will depend on your travel dates, length of stay and other factors. Compare available properties for your preferred dates and use our pricing and other filters to lock in the ideal upscale stay.

  • Search for the lowest price per night from AED 282

What makes a hotel 5 stars in Port Isabel?
Outstanding guest service is at the heart of every 5-star hotel in Port Isabel. From the minute you step through the door, staff ensure your every need is met, whether offering luggage assistance and storage or providing in-room massages. Plus, hotels must offer upscale conveniences to meet the standard for a 5-star rating. These can include luxury baths, spa facilities, swimming pools, gastronomic restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Port Isabel?
Expedia's filters are the easiest way to narrow down what you want. Check the "All inclusive" and "5-star" boxes to see the most luxurious resorts in Port Isabel where your meals, lodging, entertainment and activities are included in the upfront price. At these stays, your vacation is absolute indulgence from the moment you step foot in the lobby.

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