A cityscape with modern high-rise buildings, including a distinctive arch structure.

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Check availability on Santa Fe 5 Star Hotels

This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Santa Fe 5-star hotels

A spacious lobby with a modern staircase, two armchairs, and a large abstract wall structure.

1. Hyatt Regency Mexico City

Hyatt Regency Mexico City
5.0 star property
Polanco
9.4 out of 10, Exceptional, (1,506 reviews)
"Amazing location, Amazing Staff and Great rooms !"
United States
Angel
The price is AED 1,190
AED 1,422 total
includes taxes & fees
11 Oct - 12 Oct
Hyatt Regency Mexico City
A modern building with a glass facade, wooden deck, and potted plants.

2. Mondrian Mexico City Condesa

Mondrian Mexico City Condesa
5.0 star property
La Condesa
9.2 out of 10, Wonderful, (940 reviews)
"Great location and hotel. Good attention to detail by staff and in room amenities."
Canada
Carol
The price is AED 1,035
AED 1,236 total
includes taxes & fees
27 Oct - 28 Oct
Mondrian Mexico City Condesa
A tall, modern hotel with a prominent vertical design, large windows, and a well-lit entrance.

3. Grand Fiesta Americana Chapultepec

Grand Fiesta Americana Chapultepec
5.0 star property
Reforma
9.6 out of 10, Exceptional, (1,253 reviews)
"Wonderful stay! One of the cleanest hotel rooms I have ever had. Great location, and the staff was super kind! Thank you so much again for your hospitality!!!"
United States
Flavia
The price is AED 720
AED 860 total
includes taxes & fees
18 Oct - 19 Oct
Grand Fiesta Americana Chapultepec
A restaurant with a long table set for dining, surrounded by wicker chairs, and a large tree in the center.

4. JW Marriott Hotel Mexico City Polanco

JW Marriott Hotel Mexico City Polanco
5.0 star property
Polanco
9.4 out of 10, Exceptional, (1,000 reviews)
"Excellent"
United States
JOSE
The price is AED 2,182
AED 2,608 total
includes taxes & fees
25 Oct - 26 Oct
JW Marriott Hotel Mexico City Polanco
A clear blue pool with a city skyline in the background.

5. Andaz Condesa Mexico City, By Hyatt

Andaz Condesa Mexico City, By Hyatt
5.0 star property
La Condesa
9.2 out of 10, Wonderful, (451 reviews)
"Excellent hotel all around! Would highly recommend."
United States
Kimberly
The price is AED 1,145
AED 1,368 total
includes taxes & fees
11 Oct - 12 Oct
Andaz Condesa Mexico City, By Hyatt
An outdoor seating area with a fire pit, surrounded by lush greenery and a view of a building with balconies.

6. Four Seasons Hotel Mexico City

Four Seasons Hotel Mexico City
5.0 star property
Reforma
9.4 out of 10, Exceptional, (1,000 reviews)
"Still close too food stands."
United States
Giovanni
The price is AED 4,261
AED 5,092 total
includes taxes & fees
25 Oct - 26 Oct
Four Seasons Hotel Mexico City
A wooden deck with seating and a vertical garden wall.

7. Live Aqua Ciudad de México Bosques de las Lomas

Live Aqua Ciudad de México Bosques de las Lomas
5.0 star property
Santa Fe
9.6 out of 10, Exceptional, (1,000 reviews)
"Many places to eat and shop inside the same property"
United States
Waldemar
The price is AED 1,004
AED 1,215 total
includes taxes & fees
25 Oct - 26 Oct
Live Aqua Ciudad de México Bosques de las Lomas
A woman relaxing in a bathtub filled with water and flowers, with a cityscape view through large windows.

8. Sofitel Mexico City Reforma

Sofitel Mexico City Reforma
5.0 star property
Reforma
9.6 out of 10, Exceptional, (1,000 reviews)
"Excellent location and beautiful hotel"
United States
Fernando
The price is AED 2,311
AED 2,761 total
includes taxes & fees
25 Oct - 26 Oct
Sofitel Mexico City Reforma
A modern indoor pool area with a concrete floor, surrounded by lush greenery and a seating area with a sofa and curtains.

9. Volga, Member of Preferred Hotels & Resorts

Volga, Member of Preferred Hotels & Resorts
5.0 star property
Reforma
9.2 out of 10, Wonderful, (203 reviews)
"Property was great and in a great location. The club was closed for renovation but the restaurant food was great and the staff were attentive and helpful."
United States
Lane
The price is AED 1,375
AED 1,753 total
includes taxes & fees
28 Oct - 29 Oct
Volga, Member of Preferred Hotels & Resorts
A rooftop terrace with a hot tub, seating area, potted plants, and a city view.

10. Collections by ULIV Palacio

Collections by ULIV Palacio
5.0 star property
Polanco
9.4 out of 10, Exceptional, (320 reviews)
"Really comfortable hotel, great location, clean and great taste!"
United States
Fernando Vargas
The price is AED 748
AED 894 total
includes taxes & fees
18 Oct - 19 Oct
Collections by ULIV Palacio
A modern lounge with a curved sofa, a round table, and a city view through large windows.

11. W Mexico City

W Mexico City
5.0 star property
Polanco
8.8 out of 10, Excellent, (1,006 reviews)
"Staff were very helpful and courteous. We only had a problem with the thermostat in our room- too cold so they brought A portable heater to use. Locations was great- walking distance to a number of restaurants and parks."
United States
Lisa
The price is AED 1,553
AED 1,855 total
includes taxes & fees
24 Oct - 25 Oct
W Mexico City
A high-rise interior with a panoramic city view, modern furnishings, and a glass ceiling.

12. The Ritz-Carlton, Mexico City

The Ritz-Carlton, Mexico City
5.0 star property
Reforma
9.4 out of 10, Exceptional, (290 reviews)
"Excellent property with attentive and pleasant staff"
United States
Samuel
The price is AED 3,597
AED 4,298 total
includes taxes & fees
19 Oct - 20 Oct
The Ritz-Carlton, Mexico City
A room with a large window, two chairs, a small round table with a cup and pastry, and a view of city buildings.

13. Hyde Mexico City Reforma

Hyde Mexico City Reforma
5.0 star property
Reforma
9.2 out of 10, Wonderful, (23 reviews)
"Excellent location"
United States
Woneui
The price is AED 713
AED 853 total
includes taxes & fees
11 Oct - 12 Oct
Hyde Mexico City Reforma
A modern bar area with a curved counter, multiple seating options, and a high ceiling with geometric light fixtures.

14. Alexander, Member of The Leading Hotels of the World

Alexander, Member of The Leading Hotels of the World
5.0 star property
Miguel Hidalgo
9.4 out of 10, Exceptional, (110 reviews)
"Great hotel tos pens a short weekend"
United States
Juan Carlos
The price is AED 2,011
AED 2,587 total
includes taxes & fees
11 Oct - 12 Oct
Alexander, Member of The Leading Hotels of the World
A reception desk with a marble top, wooden panels, and a 'nomu' sign.

15. Nomu Mexico City by Lumina

Nomu Mexico City by Lumina
5.0 star property
Roma Norte
9.4 out of 10, Exceptional, (41 reviews)
"Great stay"
United States
Rodney
The price is AED 628
AED 891 total
includes taxes & fees
20 Oct - 21 Oct
Nomu Mexico City by Lumina
A rooftop pool with a cityscape view.

16. The St. Regis Mexico City

The St. Regis Mexico City
5.0 star property
Reforma
9.6 out of 10, Exceptional, (751 reviews)
"Todo excelente!"
Mexico
Rafael
The price is AED 3,112
AED 3,719 total
includes taxes & fees
9 Nov - 10 Nov
The St. Regis Mexico City
A multi-story building with balconies, a street with light trails from moving vehicles, and a speed limit sign.

17. Kukun Sócrates Polanco

Kukun Sócrates Polanco
5.0 star property
Polanco
8.8 out of 10, Excellent, (209 reviews)
"Excellent stay. We got the 3 room apt and it was perfect for us 5. It was super clean and our mattress was the best we have ever had. Pillows were soft and plenty. The staff was Excellent and very responsive to our needs. The wi-fi work perfectly. The kitchen (we had two) and 3 bathrooms were great. Its in a super safe location and you can walk anywhere. We ate most of our breakfast at the Gusina de Oaxaca and last night dinner. Its a Michelin star restaurant with great prices and excelent...
United States
Edward
The price is AED 491
AED 591 total
includes taxes & fees
11 Oct - 12 Oct
Kukun Sócrates Polanco
View from room

18. Lamartine

Lamartine
5.0 star property
Polanco
9.2 out of 10, Wonderful, (187 reviews)
"Great staff, gorgeous room, in a great area as well!"
United States
Jaysa Mia
The price is AED 824
AED 997 total
includes taxes & fees
11 Oct - 12 Oct
Lamartine
A spiral staircase with wooden steps and patterned cushions.

19. Las Alcobas, a Luxury Collection Hotel, Mexico City

Las Alcobas, a Luxury Collection Hotel, Mexico City
5.0 star property
Polanco
9.8 out of 10, Exceptional, (313 reviews)
"Small boutique hotel in a great location "
United States
TONY
The price is AED 2,090
AED 2,565 total
includes taxes & fees
2 Nov - 3 Nov
Las Alcobas, a Luxury Collection Hotel, Mexico City
A building with a balcony, a window with a decorative iron railing, and a tree in front.

20. Roso Guest House

Roso Guest House
5.0 star property
Roma Norte
9.6 out of 10, Exceptional, (103 reviews)
"Excellent to stay relaxed and be close to everything to enjoy"
United States
Georgina
The price is AED 785
AED 939 total
includes taxes & fees
6 Nov - 7 Nov
Roso Guest House
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Fe.
Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

Mexico City
The price is AED 502 per night from Nov 2 to Nov 3
AED 502
AED 600 total
2 Nov - 3 Nov
includes taxes & fees
8.8/10 Excellent! (14,155 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santa Fe Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Santa Fe?
Enjoy premium amenities and the finest level of service at Live Aqua Urban Resort México. Located around the Mexico City neighborhood of Santa Fe, this 5-star hotel is the preferred choice for many based on reviews by Expedia guests.
How much does it cost to stay in a 5-star hotel in Santa Fe?
You'll find several pricing options for a 5-star hotel in Santa Fe on Expedia. The amount you pay will depend on your travel dates, length of your trip and other factors. Compare all of the available accommodations for your desired dates and use our pricing and other filters to land the perfect high-end stay.

  • Search for the lowest price per night from AED 467

What makes a hotel 5 stars in Santa Fe?
In Santa Fe, a hotel is required to offer a specific number of top-notch amenities to earn a 5-star rating. These can include saunas and spas, on-site gyms, gourmet restaurants, complimentary luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their extraordinary standard of service. You can look forward to things like concierge services, nightly turn-down services and in-room massage. Some may also offer extra touches such as a welcome gift.

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