Search Vacation Homes in 5th and Missouri Station

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Our top choices for 5th and Missouri Station vacation homes

Vacation Home in The Gate

Entire 4BR Home near Lafayette Square
9.8 out of 10, Exceptional, (85)
"What a great stay! We had everything we needed and the owners even went out of their way to accommodate an easier way to get into the house for a family member who had a recent surgery. "
United States
Linda L.
The price is AED 512
AED 1,034 total
includes taxes & fees
22 Dec - 23 Dec
Entire 4BR Home near Lafayette Square
9.8 out of 10, Exceptional, (7)
"This was a really nice place that’s just a few minutes away from every attraction and restaurant we wanted to visit. Plenty of room and beds for a large crowd. We liked that there private off the street parking, too."
United States
Randy M.
Artsy Creative Haven Home St. Louis Art District

Vacation Home in Lafayette Square

Historic luxury retreat
9.8 out of 10, Exceptional, (162)
"Excellent spot for a family trip to St Louis. Great location and very responsive to all needs!!"
United States
Liz S.
Historic luxury retreat
9.4 out of 10, Exceptional, (6)
"Yes, we loved the property and everything was perfect to our likings. "
United States
Markquetta
Modern Downtown Haven: Near STL Zoo, Arch & Park
2.0 star property
9.8 out of 10, Exceptional, (12)
"Very clean, like new, comfy beds"
United States
Scott or Janet T.
Spacious City Retreat w/ 2 Car Garage by StayLage
7.4 out of 10, Good, (3)
"Couldn’t check in on time due to cleaning and then someone partied Next Door All night and Did Donuts in their vehicle for hrs. Until about 4am. Even Noticed police talk to them and go back to party for hrs. lol. Other days were peaceful though. "
United States
Jason H.
3BR St. Louis Home | Games + Free Parking
9.4 out of 10, Exceptional, (50)
"It was very good stay! Thank you! "
United States
Trey S.
Rustic Charm 4BDRM Home| STL Developers
9.8 out of 10, Exceptional, (34)
"Awesome property for our group. "
United States
Justin R.
Modern & Luxurious. 4BR. Sleep 12. Minutes to downtown
9.0 out of 10, Wonderful, (2)
"Older home with nice modern touches. Ample space for larger groups. Fully stocked kitchen is always a plus. Hosts were great at communicating prior and during our visit. Really cool little golf cart community only minutes from downtown area."
United States
Matthew M.
3-bedroom house in charming St. Louis historic district Free shuttle to games
9.6 out of 10, Exceptional, (45)
"Great location. Great communication and support from the owner. Lots of bathrooms and beds! Spacious living room with lots of seating. Large table for meals (lots of chairs). Great place for a family gathering. We had 14 and fit very comfortably."
United States
Tim P.
Beautiful 6BR Fox Park Home // 1st Floor Master Bed and Bath + Private Parking!
2.0 star property
Uptown Elegant Escape | JZ Vacation Rentals
The Gathering Spot Downtown St. Louis by StayLage
3.5 star property
Welcoming Lafayette Square Home - JZ Vacation Rentals

Vacation Home in Benton Park

Historic Benton Park HUGE 2 BR Condo
8.4 out of 10, Very Good, (5)
"Place was exactly as advertised. Its a huge and spacious space. The hubby and I enjoyed our stay!"
United States
Melissa M.
Historic Benton Park HUGE 2 BR Condo

Vacation Home in The Gate

A Cottage in Downtown STL. Sleeps 10
2.0 star property
2.0 out of 10, (1)
"Live mice in upstairs bedroom and in kitchen cabinet. Soiled blankets and sofa. Dishwasher had standing water and smelled horrible as did the entire first floor. Did not feel comfortable using anything in kitchen due to mouse droppings and other sanitary issues. The first night we saw a mouse upstairs and contacted the host, the response was “is it still there?” No empathy, no apologies. It was a poor night of sleep for the entire family as we worried. The next morning, a mouse dropped from a...
United States
Mandi
A Cottage in Downtown STL. Sleeps 10

Vacation Home in Lafayette Square

The Marquis Manor | JZ Vacation Rentals
3.0 star property
The Marquis Manor | JZ Vacation Rentals
9.6 out of 10, Exceptional, (24)
"This house was beautiful and in a very nice spot in St. Louis. Close to everything and the hosts were amazing. Would definitely use again "
United States
Justin B.
The price is AED 479
AED 957 total
includes taxes & fees
14 Dec - 15 Dec
Brand New! Soulard Charmer - Pet Friendly.

Vacation Home in Old North Saint Louis

4bed/3bath House in St. Louis
9.2 out of 10, Wonderful, (22)
"Very beautiful and spacious home and yard. Plenty of bedrooms. The whole group enjoyed their stay. If we are ever back in St Louis, would rent it again"
United States
rachel h.
4bed/3bath House in St. Louis

Vacation Home in McKinley Heights

3 King Beds/Charm in Historic STL by StayStlouis
9.6 out of 10, Exceptional, (14)
"Location was great for our stay. Property was very clean and had everything we needed. Our kids loved the foosball table!"
United States
Troy O.
The price is AED 694
AED 1,532 total
includes taxes & fees
4 Jan - 5 January 2026
3 King Beds/Charm in Historic STL by StayStlouis
9.8 out of 10, Exceptional, (30)
"Beautiful neighborhood very clean and the host was super "
United States
alice u.
The price is AED 676
AED 1,488 total
includes taxes & fees
6 Jan - 7 January 2026
King Beds/3Baths Renovated Spacious By StayStLouis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top 5th and Missouri Station Hotel Reviews