The Best Hotels Closest to Buffalo Museum of Science in Buffalo for 2026

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Our top choices for Buffalo Museum of Science hotels

A grand staircase with ornate woodwork and a chandelier, leading to a room with a large wooden door and a stained glass window.

1. InnBuffalo off Elmwood

Elmwood Village, 3 km from Buffalo Museum of Science

Terese

AED 474 total

includes taxes & fees

12 Nov - 13 Nov

A spacious room with a wooden floor, a fireplace, a dining table, and several chairs.

2. Buffalo Harmony House

Allentown, 3.2 km from Buffalo Museum of Science

John

AED 1,385 total

includes taxes & fees

11 Nov - 12 Nov

A spacious dining area with a long table, multiple chairs, a chandelier, and a fireplace.

3. The Edward Hotel

Elmwood Village, 2.4 km from Buffalo Museum of Science

Grace

AED 731 total

includes taxes & fees

15 Nov - 16 Nov

A two-story building with a white exterior, a red door, and large windows.

4. Buffalo Guesthouse

Allentown, 2.4 km from Buffalo Museum of Science

Jose

AED 697 total

includes taxes & fees

9 Nov - 10 Nov

A grand entrance with a staircase leading to a door, surrounded by lush greenery and a well-maintained garden.

5. The Mansion On Delaware Ave

Allentown, 3 km from Buffalo Museum of Science

Marilyn

AED 831 total

includes taxes & fees

12 Nov - 13 Nov

A modern hotel lobby with a bar area, seating, and a large TV screen.

6. Residence Inn by Marriott Buffalo Downtown

Allentown, 2.6 km from Buffalo Museum of Science

Karen

AED 798 total

includes taxes & fees

24 Nov - 25 Nov

A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.

7. Wyndham Garden Buffalo Downtown

Downtown Buffalo, 1.9 km from Buffalo Museum of Science

Sara

AED 675 total

includes taxes & fees

9 Nov - 10 Nov

A hotel room with a bed, desk, chair, TV, and a bathroom with a sink and mirror.

8. Best Western on the Avenue

Allentown, 2.8 km from Buffalo Museum of Science

James

AED 652 total

includes taxes & fees

23 Nov - 24 Nov

A hotel lobby with seating areas, a coffee table, and a lamp.

9. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Buffalo Theater District, 3.1 km from Buffalo Museum of Science

Daniel

AED 519 total

includes taxes & fees

8 Dec - 9 Dec

A dining area with a wooden table and chairs, a fireplace, and large windows with a view of greenery outside.

10. Summer Street Guest House

Bryant, 3 km from Buffalo Museum of Science

Anthony

AED 1,905 total

includes taxes & fees

23 Nov - 24 Nov

A lobby with a staircase, seating area, and a view of the outdoors.

11. Lenox Hotel and Suites

Allentown, 2.6 km from Buffalo Museum of Science

Thomas

AED 446 total

includes taxes & fees

8 Dec - 9 Dec

A rooftop terrace with wicker furniture, a bar area, and a view of the cityscape.

12. Aloft by Marriott Buffalo Downtown

Buffalo Theater District, 3 km from Buffalo Museum of Science

Anthony T

AED 768 total

includes taxes & fees

29 Nov - 30 Nov

A hotel room with a large bed, a desk with a chair, a bathroom with a bathtub, and a mirror.

13. Salvatores Grand Hotel

13.1 km from Buffalo Museum of Science

Mary

AED 706 total

includes taxes & fees

22 Nov - 23 Nov

A hotel with a prominent entrance, a clock tower, and the name "REIKART HOUSE" displayed above the entrance.

14. Reikart House, Buffalo, a Tribute Portfolio Hotel

8.3 km from Buffalo Museum of Science

Jonathon

AED 936 total

includes taxes & fees

15 Nov - 16 Nov

15. Hampton Inn Buffalo - Amherst, NY

10.6 km from Buffalo Museum of Science

Lee

AED 458 total

includes taxes & fees

29 Nov - 30 Nov

A lobby with teal armchairs, a round table, a flat-screen TV, and a stone wall with a fireplace.

16. The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

9 km from Buffalo Museum of Science

Andres

AED 693 total

includes taxes & fees

15 Nov - 16 Nov

A large indoor swimming pool with clear blue water, surrounded by lounge chairs and a sauna area.

17. Hampton Inn Buffalo-Williamsville

9.6 km from Buffalo Museum of Science

Robert

AED 600 total

includes taxes & fees

15 Nov - 16 Nov

A patio area with outdoor seating, a barbecue grill, and a stone wall.

18. Tru by Hilton Williamsville Buffalo Airport

13 km from Buffalo Museum of Science

Stephen P

AED 458 total

includes taxes & fees

30 Nov - 1 Dec

A modern dining area with multiple tables and chairs, a long communal table, and a counter with a TV.

19. Springhill Suites Buffalo Airport

13 km from Buffalo Museum of Science

Matthias

AED 598 total

includes taxes & fees

7 Dec - 8 Dec

A modern hotel room with a large window, a sofa, a coffee table, and a TV.

20. Buffalo Marriott at LECOM HARBORCENTER

Downtown Buffalo, 4.4 km from Buffalo Museum of Science

Stephen

AED 1,017 total

includes taxes & fees

19 Nov - 20 Nov

View all properties

Compare top hotels near Buffalo Museum of Science

InnBuffalo off Elmwood 2.5 star property Elmwood Village, 3 km from Buffalo Museum of Science View	Buffalo Harmony House 4.5 star property Allentown, 3.2 km from Buffalo Museum of Science View	The Edward Hotel 3.0 star property Elmwood Village, 2.4 km from Buffalo Museum of Science View	Buffalo Guesthouse 4.0 star property Allentown, 2.4 km from Buffalo Museum of Science View	The Mansion On Delaware Ave 4.0 star property Allentown, 3 km from Buffalo Museum of Science View
10.0 Exceptional 225 reviews	10.0 Exceptional 58 reviews	9.6 Exceptional 270 reviews	9.4 Exceptional 231 reviews	9.4 Exceptional 1,004 reviews
The price is AED 413 AED 474 total includes taxes & fees 12 Nov - 13 Nov	The price is AED 1,191 AED 1,385 total includes taxes & fees 11 Nov - 12 Nov	The price is AED 531 AED 731 total includes taxes & fees 15 Nov - 16 Nov	The price is AED 607 AED 697 total includes taxes & fees 9 Nov - 10 Nov	The price is AED 724 AED 831 total includes taxes & fees 12 Nov - 13 Nov
Yes, Breakfast included No Pool No Spa No Pet friendly Yes, WiFi included Yes, Parking	Yes, Breakfast included No Pool No Spa No Pet friendly Yes, WiFi included No Parking	No Breakfast included No Pool No Spa No Pet friendly Yes, WiFi included Yes, Parking	Yes, Breakfast included Yes, Pool No Spa No Pet friendly Yes, WiFi included No Parking	Yes, Breakfast included No Pool No Spa No Pet friendly Yes, WiFi included Yes, Parking

Other attractions near Buffalo Museum of Science

Buffalo Central Terminal

You can find out about the history of Buffalo when you stop by Buffalo Central Terminal. Experience the entertainment choices and great live music in this vibrant area.

See properties

Top Buffalo Museum of Science Hotel Reviews

InnBuffalo off Elmwood

Elmwood Village

10/10 Excellent

Lerran

The Edward Hotel

Elmwood Village

10/10 Excellent

Dawn

The Mansion On Delaware Ave

Downtown Buffalo

10/10 Excellent

Evan

A circular fire pit with a metal railing, surrounded by a stone base, set on a tiled patio with a city skyline in the background.

Curtiss Hotel, an Ascend Collection Hotel

Downtown Buffalo

10/10 Excellent

Eric

Buffalo Marriott at LECOM HARBORCENTER

Downtown Buffalo

10/10 Excellent

Anonymous traveler

Reikart House, Buffalo, a Tribute Portfolio Hotel

Buffalo

10/10 Excellent

We were so pleasantly surprised when we arrived at the hotel. We travel to Buffalo often, family and our daughter is in college there. We have stayed in many hotels in the area but none were as charming, beautifully designed, clean, and had a staff that was available for anything you needed. The lobby is like being in someones beautifully decorated living room. Our room was lovely with a very comfortable bed and a small living room wtth a pull out sofa. Thanks for the candy when we arrived...

Anonymous traveler

Residence Inn by Marriott Buffalo Downtown

Downtown Buffalo

10/10 Excellent

Anonymous traveler

A spacious lobby with modern furniture, large windows, and a high ceiling with exposed beams.

The Westin Buffalo

Downtown Buffalo

10/10 Excellent

Jamal

Wyndham Garden Buffalo Downtown

Downtown Buffalo

10/10 Excellent

Kelly

Salvatores Grand Hotel

Buffalo

10/10 Excellent

This is a beautiful hotel. Our king suite was so very nice. Having a top rated restaurant right there was amazing and the breakfast next morning was delicious and well stocked. I can't wait to visit again and take some other family members. My husband said he would drive the 3 hours from where we live just to stay at the hotel and dine at Russells. That is saying something because he is not a traveler. The Christmas decorations were so very festive. We were there for a wake and memorial service...

Dawn

The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

Buffalo

10/10 Excellent

Marc

Hampton Inn Buffalo - Amherst, NY

Buffalo

10/10 Excellent

Sarah

A modern outdoor patio with stone walls, a fire feature, and outdoor furniture.

Courtyard Buffalo Downtown / Canalside

Downtown Buffalo

10/10 Excellent

Staff was polite and helpful. Too many chemicals in pool burned my son's eyes. Will bring goggles next time. He didn't even open his eyes under water. But I understand the use of chemicals to keep it clean. Only negative thing was another young couple came down in the evening to use the pool and were very inappropriate in the pool area in front of my children. Not hotels fault. But we left earlier than we would have so they didn't have to see them doing what they were doing.

Theresa

Hampton Inn Buffalo-Williamsville

Buffalo

10/10 Excellent

Erica

An outdoor patio with a fire pit, seating, and string lights.

Home2 Suites by Hilton Buffalo Airport / Galleria Mall

Buffalo

10/10 Excellent

Pam

Best Western on the Avenue

Downtown Buffalo

10/10 Excellent

Marc J

A hotel with a prominent red sign, large windows, and a parking lot with multiple cars.

Hampton Inn & Suites Buffalo Downtown

Downtown Buffalo

10/10 Excellent

Vanessa

Frequently Asked Questions

What's the area like around Buffalo Museum of Science?

Buffalo Museum of Science is located in a historic area of Buffalo known for its great live music scene. If you're looking for a convenient place to stay, check out the 14 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay near Buffalo Museum of Science?

Wyndham Garden Buffalo Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. It's located 1.2 mi (1.9 km) from Buffalo Museum of Science. Other good choices within 5 miles include Hyatt Regency Buffalo / Hotel and Conference Center and Buffalo Guesthouse.

How many hotels will I be able to find close to Buffalo Museum of Science?

Expedia has 14 hotels and other accommodations within a mile from Buffalo Museum of Science.

If I need to cancel the hotel reservation for my stay near Buffalo Museum of Science, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the top deals on offer near Buffalo Museum of Science.

Where can I learn more about changing or cancelling my trip in the area near Buffalo Museum of Science?

For more information about picking new dates or cancelling your stay near Buffalo Museum of Science, go to https://www.expedia.com/service/.

What can I see and do near Buffalo Museum of Science?

Study the collections at Buffalo AKG Art Museum, Buffalo History Museum, or Buffalo and Erie County Naval and Military Park. Some landmarks that you won't want to miss include Buffalo Central Terminal, Statler Tower, and Richardson Olmsted Complex. You can watch performances at Kleinhans Music Hall, Town Ballroom, and Road Less Traveled Productions if you're interested in local theater.

Find hotels near Buffalo Museum of Science, Buffalo from AED 413

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Our top choices for Buffalo Museum of Science hotels

1. InnBuffalo off Elmwood

2. Buffalo Harmony House

3. The Edward Hotel

4. Buffalo Guesthouse

5. The Mansion On Delaware Ave

6. Residence Inn by Marriott Buffalo Downtown

7. Wyndham Garden Buffalo Downtown

8. Best Western on the Avenue

9. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

10. Summer Street Guest House

11. Lenox Hotel and Suites

12. Aloft by Marriott Buffalo Downtown

13. Salvatores Grand Hotel

14. Reikart House, Buffalo, a Tribute Portfolio Hotel

15. Hampton Inn Buffalo - Amherst, NY

16. The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

17. Hampton Inn Buffalo-Williamsville

18. Tru by Hilton Williamsville Buffalo Airport

19. Springhill Suites Buffalo Airport

20. Buffalo Marriott at LECOM HARBORCENTER

Compare top hotels near Buffalo Museum of Science

InnBuffalo off Elmwood

Buffalo Harmony House

The Edward Hotel

Buffalo Guesthouse

The Mansion On Delaware Ave

Other attractions near Buffalo Museum of Science

Buffalo Central Terminal

Top Buffalo Museum of Science Hotel Reviews

InnBuffalo off Elmwood

10/10 Excellent

Frequently Asked Questions

What's the area like around Buffalo Museum of Science?

What's the best hotel to stay near Buffalo Museum of Science?

How many hotels will I be able to find close to Buffalo Museum of Science?

If I need to cancel the hotel reservation for my stay near Buffalo Museum of Science, will I receive a refund?

Where can I learn more about changing or cancelling my trip in the area near Buffalo Museum of Science?

What can I see and do near Buffalo Museum of Science?