Find Family Hotels in Cairo, IL

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Check availability on Cairo Family Hotels

Tonight
30 Sep - 1 Oct
Tomorrow
1 Oct - 2 Oct
This weekend
3 Oct - 5 Oct
Next weekend
10 Oct - 12 Oct

Top Cairo Family Hotels

Super 8 by Wyndham Charleston/Sikeston East MO
Front of property - evening/night

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (593)
"Thank you!!!"
The price is AED 209
AED 232 total
includes taxes & fees
5 Oct - 6 Oct
Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Cairo I-57
Lobby

Quality Inn Cairo I-57

2.5 star property
6.6 out of 10, (270)
"Break fast was excellent "
The price is AED 250
AED 277 total
includes taxes & fees
6 Oct - 7 Oct
Quality Inn Cairo I-57
Quality Inn Charleston - Sikeston
Desk, laptop workspace, blackout drapes, iron/ironing board

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (403)
"I consistently choose to stay there due to positive past encounters."
The price is AED 241
AED 268 total
includes taxes & fees
28 Oct - 29 Oct
Quality Inn Charleston - Sikeston
The Hickory Chicken "Hard to find, worth the search"
Terrace/patio

The Hickory Chicken "Hard to find, worth the search"

The price is AED 441
AED 649 total
includes taxes & fees
2 Oct - 3 Oct
The Hickory Chicken "Hard to find, worth the search"
Hickory Hideaway - 4 Bedroom /2 Bath in quiet country setting
Terrace/patio

Hickory Hideaway - 4 Bedroom /2 Bath in quiet country setting

The price is AED 514
AED 967 total
includes taxes & fees
2 Oct - 3 Oct
Hickory Hideaway - 4 Bedroom /2 Bath in quiet country setting
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cairo Hotel Reviews

Quality Inn Cairo I-57

Quality Inn Cairo I-57

10/10 Excellent
"Break fast was excellent "
Uma 1-night trip
Posted 3 days ago
Quality Inn Cairo I-57

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's Cairo like for family-friendly vacations?
You might want to consider the historic destination of Cairo if you've been thinking about a trip for the whole family. The entertainment, restaurants, and libraries are just a few things that make this an attractive spot for a family vacation. Arrange a flight into Cairo, IL (CIR-Cairo Regional), which is the closest airport, or Paducah, KY (PAH-Barkley Regional), which is located 22.9 mi (36.8 km) from the city center.
What's the best hotel for a family vacation to Cairo?
Quality Inn Cairo I-57 is a hotel with free parking and free breakfast, and it's a top choice on Expedia for families.
When's the best time to book a family-friendly vacation in Cairo?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.
What's there to see and do with your family in Cairo?
While you and the family are vacationing in Cairo, you might want to get outside and enjoy the great outdoors at spots such as Mississippi River, Shawnee National Forest, and Ohio River. Make sure you have time to check out activities like Ballard Wildlife Management Area and Fort Defiance State Park.