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Check prices for these dates

Next weekend
9 Jan - 11 Jan
In two weeks
16 Jan - 18 Jan
In one month
30 Jan - 1 Feb
In two months
27 Feb - 1 Mar

Our top choices for Cairo motels

Front of property - evening/night
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (615)
"Staff was great! Room was nice. "
United States
Lana
The price is AED 228
AED 253 total
includes taxes & fees
2 Jan - 3 Jan
Super 8 by Wyndham Charleston/Sikeston East MO
Desk, iron/ironing board, free WiFi, alarm clocks
Eagle Inn Charleston

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (105)
"Middle of nowhere hotel was ok"
United States
David
The price is AED 222
AED 247 total
includes taxes & fees
2 Jan - 3 Jan
Eagle Inn Charleston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cairo Hotel Reviews

Charming 3-bedroom house near ball park in quiet neighborhood

Charming 3-bedroom house near ball park in quiet neighborhood

10/10 Excellent
"This was the perfect house for our stay while visiting our grandkids! Very cozy & clean & we had everything we needed to make meals & enjoy time with family."
mary p. 5-night trip
Posted 2 weeks ago
Charming 3-bedroom house near ball park in quiet neighborhood

Frequently asked questions

What can I expect from a motel trip to Cairo?
If you're having difficulty finding a motel in Cairo, let Expedia help you find motels or similar properties from more than 25 lodging options in the larger area. Simply use our search tools to filter by nightly room rate or cost-saving amenities such as free breakfast and free airport transportation.
What's it like to stay in a motel?
When you stay at a motel, you're likely to find a free parking spot and an outdoor pool. With a stay at a motel, you'll often have access to your room from an outside corridor overlooking the parking lot. The word "motel" was conceived in 1925 in San Luis Obispo, California by the owner of the Milestone Mo-Tel.
What are the best motels in Cairo?
Here you'll find some of our customers' favorite motels to book in the larger area. Super 8 by Wyndham Charleston/Sikeston East MO is located 10 mi (16.2 km) from the heart of Cairo. Enjoy access to the business center, and freebies including breakfast, WiFi, and parking. Eagle Inn Charleston: Free WiFi and free parking are available during your stay, along with room amenities like a microwave. Central Cairo is 9.3 mi (14.9 km) away.
What can I do in Cairo?
Enjoy nature with a stop at Mississippi River and Ohio River Valley. While you're checking out the area, consider visiting Fort Defiance State Park, Ballard Wildlife Management Area, and Columbus-Belmont State Park.
What's the seasonal weather like in Cairo?
Weather can make or break a roadtrip, so we've gathered some data about year-round temperatures in Cairo to help you plan yours. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.
What are my options for getting around Cairo when staying in a motel?
We've gathered some information about getting around Cairo to help you navigate your stay: Fly into Cairo, IL (CIR-Cairo Regional), which is located 4.7 mi (7.5 km) away from the city center. Otherwise, you can search for flights to Paducah, KY (PAH-Barkley Regional), which is 22.9 mi (36.8 km) away. If you'd like to explore around the area, you may want to rent a car for your trip.