Find all hotels by Premier Inn in Cape Girardeau, MO
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Tonight
27 Aug - 28 AugTomorrow
28 Aug - 29 AugThis weekend
28 Aug - 30 AugNext weekend
4 Sep - 6 Sep
Save an average of 15% on thousands of hotels when you're signed in
Top Cape Girardeau Hotel Reviews
Pear Tree Inn Cape Girardeau West
10/10 Excellent
"Our one-night stay was very pleasant. The room was comfortable and clean, and it was suitable for my husband, our cat, and me. The staff was friendly and professional. The location was convenient, close to restaurants and the highway. We look forward to staying here again."
Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
"Competitively priced. Complimentary happy hour and hot breakfast were exceptional. We stay at a Drury Inn whenever they are available."
Fairfield Inn & Suites by Marriott Cape Girardeau
10/10 Excellent
"Good breakfast selection"
Courtyard by Marriott Cape Girardeau Downtown
10/10 Excellent
"This hotel built in the 1900s was renovated in 2018 and is absolutely gorgeous. The room was large and very clean. You could walk to everything. We stumbled onto a Cajun restaurant and bar that happened to have live music and the food was good"
Tru By Hilton Cape Girardeau
8/10 Good
"Staff was friendly and welcoming."
Drury Inn & Suites Cape Girardeau
10/10 Excellent
"The staff at the location were very accommodating. Check to make sure everything was good. The breakfast was awesome. I was concerned that the pool was being under construction and that was not sent out to people that are planning or had planned to stay there. I was looking forward to the pool and if have been a hot tub."
“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau
10/10 Excellent
"Beautiful house. Polite and accommodating owner. Wonderful stay"
The Riverview
8/10 Good
"Nice view of the river. The staff was nice."
3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau
10/10 Excellent
"Is a very welcoming home. Stayed there with my family and my kids loved the house. Is very big and spacious. A lot of amenities was provided like kitchen supplies, extra blankets and towels. The only thing I will change would be the entrance glass door even dough my dog loved it my kids were a little scared that people will look inside But other than that everything was really good. Thank you"
Explore a world of travel with Expedia
- Motel 6 Hotels in Sikeston
- Best Western Hotels in Bloomfield
- Pet-Friendly Hotels in Cape Girardeau
- Independent Hotels in Friedheim
- Family Hotels in Cape Girardeau
- Drury Inn & Suites Hotels in Cape Girardeau
- Wyndham Hotels in Oran
- Wyndham Hotels in Bertrand
- Independent Hotels in Sikeston
- Red Carpet Inn Hotels in Bloomfield
- Hotels with Hot Tubs in Cape Girardeau
- Drury Inn & Suites Hotels in Perryville
- Cabin Rentals in Jackson
- Casino Hotels in Cape Girardeau
- Aimbridge Hospitality Hotels in Bertrand
- Wyndham Hotels in Bloomfield
- Aimbridge Hospitality Hotels in Cape Girardeau
- Casino Hotels in Jackson
- Aimbridge Hospitality Hotels in Oran
- Best Western Hotels in Oran
- Wyndham Hotels in Sedgewickville
- Country Hearth Inn Hotels in Bertrand
- Adults Only Resorts & in Cape Girardeau
- 4 Star Hotels in Jackson
- Independent Hotels in Marble Hill
- Motels in Cape Girardeau
- Drury Inn & Suites Hotels in Sikeston
- Cabin Rentals in Cape Girardeau
- Drury Inn & Suites Hotels in Jackson
- Best Western Hotels in Charleston
- Lodges in Jackson
- Wyndham Hotels in Friedheim
- Hilton Hotels in Sikeston
- Cape Girardeau Hotels
- 5 Star Hotels in Jackson
- Flights from Zacatecas (ZCL) to Cape Girardeau (CGI)
- Flights from Muskegon (MKG) to Cape Girardeau (CGI)
- Flights from Huntsville (HSV) to Cape Girardeau (CGI)
- Flights from Waterloo (ALO) to Cape Girardeau (CGI)
- Flights from Bridgeport (BDR) to Cape Girardeau (CGI)
- Flights from Maputo (MPM) to Cape Girardeau (CGI)
- Flights from Decatur (DEC) to Cape Girardeau (CGI)
- Flights from Lac La Martre (YLE) to Cape Girardeau (CGI)
- Flights from Corinth (CRX) to Cape Girardeau (CGI)
- Flights from Milan (MIL) to Cape Girardeau (CGI)
- Flights from Asmara (ASM) to Cape Girardeau (CGI)
- Flights from Augusta (AUG) to Cape Girardeau (CGI)
- Flights from Jackson
- Flights from White Plains (HPN) to Cape Girardeau (CGI)
- Flights from Qingdao (TAO) to Cape Girardeau (CGI)
- Flights from Bismarck (BIS) to Cape Girardeau (CGI)
- Flights from Cold Bay (CDB) to Cape Girardeau (CGI)
- Flights from Campos (CAW) to Cape Girardeau (CGI)
- Flights from Salerno (QSR) to Cape Girardeau (CGI)
- Flights from Eek (EEK) to Cape Girardeau (CGI)
- Flights from Killeen (ILE) to Cape Girardeau (CGI)
- Flights from Havre (HVR) to Cape Girardeau (CGI)
- Flights from Vopnafjordur (VPN) to Cape Girardeau (CGI)
- Flights from Stuttgart (STR) to Cape Girardeau (CGI)
- Flights from Birmingham (BHX) to Cape Girardeau (CGI)
- Flights from Torreón (TRC) to Cape Girardeau (CGI)
- Flights from Cape Girardeau Municipal
- Flights from Harrison (HRO) to Cape Girardeau (CGI)
- Flights from Nairobi (NBO) to Cape Girardeau (CGI)
- Flights from Palm Springs (PSP) to Cape Girardeau (CGI)
- Flights from Kenosha (ENW) to Cape Girardeau (CGI)
- Flights from Georgetown (GEO) to Cape Girardeau (CGI)
- Flights from Baku (GYD) to Cape Girardeau (CGI)
- Flights from Prescott (PRC) to Cape Girardeau (CGI)
- Flights from Winchester (WGO) to Cape Girardeau (CGI)
- Flights from Atqasuk (ATK) to Cape Girardeau (CGI)
- Flights from Kullu (KUU) to Cape Girardeau (CGI)
- Flights from London (LGW) to Cape Girardeau (CGI)
- Flights from Yakima (YKM) to Cape Girardeau (CGI)
- Flights from New Bern (EWN) to Cape Girardeau (CGI)
- Flights from Perth (PSL) to Cape Girardeau (CGI)
- Flights from Leeds (LBA) to Cape Girardeau (CGI)
- Flights from Juneau (JNU) to Cape Girardeau (CGI)
- Flights from Shanghai (PVG) to Cape Girardeau (CGI)
- Flights from Sioux City (SUX) to Cape Girardeau (CGI)
- Flights from Cortez (CEZ) to Cape Girardeau (CGI)
- Flights from Lisbon (LIS) to Cape Girardeau (CGI)
- Flights from Rio Gallegos (RGL) to Cape Girardeau (CGI)
- Flights from Santa Cruz de Tenerife (TFN) to Cape Girardeau (CGI)
- Flights from Louisville (LOU) to Cape Girardeau (CGI)
- Flights from Kansas City (MCI) to Cape Girardeau (CGI)
- Flights from Gulfport (GPT) to Cape Girardeau (CGI)
- Flights from Orlando (MCO) to Cape Girardeau (CGI)
- Flights from Cat Cay (CXY) to Cape Girardeau (CGI)
- Flights from Nantucket (ACK) to Cape Girardeau (CGI)
- Flights from Ithaca (ITH) to Cape Girardeau (CGI)
- Flights from Argostolion (EFL) to Cape Girardeau (CGI)
- Flights from Bellingham (BLI) to Cape Girardeau (CGI)
- Flights from Bartlesville (BVO) to Cape Girardeau (CGI)
- Flights from Grand Island (GRI) to Cape Girardeau (CGI)
- Flights from Fayetteville (FYV) to Cape Girardeau (CGI)
- Flights from Gary (GYY) to Cape Girardeau (CGI)