Find all hotels by Premier Inn in Cape Girardeau, MO
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Tonight
28 Aug - 29 AugTomorrow
29 Aug - 30 AugThis weekend
28 Aug - 30 AugNext weekend
4 Sep - 6 Sep
Save an average of 15% on thousands of hotels when you're signed in
Top Cape Girardeau Hotel Reviews
Candlewood Suites Cape Girardeau by IHG
10/10 Excellent
"Wonderful stay. Clean, quiet, friendly staff. Will choose Candlewood again."
Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
"Competitively priced. Complimentary happy hour and hot breakfast were exceptional. We stay at a Drury Inn whenever they are available."
Fairfield Inn & Suites by Marriott Cape Girardeau
10/10 Excellent
"Good breakfast selection"
Courtyard by Marriott Cape Girardeau Downtown
10/10 Excellent
"This hotel built in the 1900s was renovated in 2018 and is absolutely gorgeous. The room was large and very clean. You could walk to everything. We stumbled onto a Cajun restaurant and bar that happened to have live music and the food was good"
Tru By Hilton Cape Girardeau
8/10 Good
"Staff was friendly and welcoming."
Drury Inn & Suites Cape Girardeau
10/10 Excellent
"The staff at the location were very accommodating. Check to make sure everything was good. The breakfast was awesome. I was concerned that the pool was being under construction and that was not sent out to people that are planning or had planned to stay there. I was looking forward to the pool and if have been a hot tub."
“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau
10/10 Excellent
"Beautiful house. Polite and accommodating owner. Wonderful stay"
The Riverview
8/10 Good
"Nice view of the river. The staff was nice."
3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau
10/10 Excellent
"Is a very welcoming home. Stayed there with my family and my kids loved the house. Is very big and spacious. A lot of amenities was provided like kitchen supplies, extra blankets and towels. The only thing I will change would be the entrance glass door even dough my dog loved it my kids were a little scared that people will look inside But other than that everything was really good. Thank you"
Explore a world of travel with Expedia
- Motel 6 Hotels in Sikeston
- Best Western Hotels in Bloomfield
- Pet-Friendly Hotels in Cape Girardeau
- Independent Hotels in Friedheim
- Family Hotels in Cape Girardeau
- Drury Inn & Suites Hotels in Cape Girardeau
- Wyndham Hotels in Oran
- Wyndham Hotels in Bertrand
- Independent Hotels in Sikeston
- Red Carpet Inn Hotels in Bloomfield
- Hotels with Hot Tubs in Cape Girardeau
- Drury Inn & Suites Hotels in Perryville
- Cabin Rentals in Jackson
- Casino Hotels in Cape Girardeau
- Aimbridge Hospitality Hotels in Bertrand
- Wyndham Hotels in Bloomfield
- Aimbridge Hospitality Hotels in Cape Girardeau
- Casino Hotels in Jackson
- Aimbridge Hospitality Hotels in Oran
- Best Western Hotels in Oran
- Wyndham Hotels in Sedgewickville
- Country Hearth Inn Hotels in Bertrand
- Adults Only Resorts & in Cape Girardeau
- 4 Star Hotels in Jackson
- Independent Hotels in Marble Hill
- Motels in Cape Girardeau
- Drury Inn & Suites Hotels in Sikeston
- Cabin Rentals in Cape Girardeau
- Drury Inn & Suites Hotels in Jackson
- Best Western Hotels in Charleston
- Lodges in Jackson
- Wyndham Hotels in Friedheim
- Hilton Hotels in Sikeston
- Cape Girardeau Hotels
- 5 Star Hotels in Jackson
- Flights from Zacatecas (ZCL) to Cape Girardeau (CGI)
- Flights from Muskegon (MKG) to Cape Girardeau (CGI)
- Flights from Huntsville (HSV) to Cape Girardeau (CGI)
- Flights from Waterloo (ALO) to Cape Girardeau (CGI)
- Flights from Bridgeport (BDR) to Cape Girardeau (CGI)
- Flights from Maputo (MPM) to Cape Girardeau (CGI)
- Flights from Decatur (DEC) to Cape Girardeau (CGI)
- Flights from Lac La Martre (YLE) to Cape Girardeau (CGI)
- Flights from Corinth (CRX) to Cape Girardeau (CGI)
- Flights from Milan (MIL) to Cape Girardeau (CGI)
- Flights from Asmara (ASM) to Cape Girardeau (CGI)
- Flights from Augusta (AUG) to Cape Girardeau (CGI)
- Flights from Jackson
- Flights from White Plains (HPN) to Cape Girardeau (CGI)
- Flights from Qingdao (TAO) to Cape Girardeau (CGI)
- Flights from Bismarck (BIS) to Cape Girardeau (CGI)
- Flights from Cold Bay (CDB) to Cape Girardeau (CGI)
- Flights from Campos (CAW) to Cape Girardeau (CGI)
- Flights from Salerno (QSR) to Cape Girardeau (CGI)
- Flights from Eek (EEK) to Cape Girardeau (CGI)
- Flights from Killeen (ILE) to Cape Girardeau (CGI)
- Flights from Havre (HVR) to Cape Girardeau (CGI)
- Flights from Vopnafjordur (VPN) to Cape Girardeau (CGI)
- Flights from Stuttgart (STR) to Cape Girardeau (CGI)
- Flights from Birmingham (BHX) to Cape Girardeau (CGI)
- Flights from Torreón (TRC) to Cape Girardeau (CGI)
- Flights from Cape Girardeau Municipal
- Flights from Harrison (HRO) to Cape Girardeau (CGI)
- Flights from Nairobi (NBO) to Cape Girardeau (CGI)
- Flights from Palm Springs (PSP) to Cape Girardeau (CGI)
- Flights from Kenosha (ENW) to Cape Girardeau (CGI)
- Flights from Georgetown (GEO) to Cape Girardeau (CGI)
- Flights from Baku (GYD) to Cape Girardeau (CGI)
- Flights from Prescott (PRC) to Cape Girardeau (CGI)
- Flights from Winchester (WGO) to Cape Girardeau (CGI)
- Flights from Atqasuk (ATK) to Cape Girardeau (CGI)
- Flights from Kullu (KUU) to Cape Girardeau (CGI)
- Flights from London (LGW) to Cape Girardeau (CGI)
- Flights from Yakima (YKM) to Cape Girardeau (CGI)
- Flights from New Bern (EWN) to Cape Girardeau (CGI)
- Flights from Perth (PSL) to Cape Girardeau (CGI)
- Flights from Leeds (LBA) to Cape Girardeau (CGI)
- Flights from Juneau (JNU) to Cape Girardeau (CGI)
- Flights from Shanghai (PVG) to Cape Girardeau (CGI)
- Flights from Sioux City (SUX) to Cape Girardeau (CGI)
- Flights from Cortez (CEZ) to Cape Girardeau (CGI)
- Flights from Lisbon (LIS) to Cape Girardeau (CGI)
- Flights from Rio Gallegos (RGL) to Cape Girardeau (CGI)
- Flights from Santa Cruz de Tenerife (TFN) to Cape Girardeau (CGI)
- Flights from Louisville (LOU) to Cape Girardeau (CGI)
- Flights from Kansas City (MCI) to Cape Girardeau (CGI)
- Flights from Gulfport (GPT) to Cape Girardeau (CGI)
- Flights from Orlando (MCO) to Cape Girardeau (CGI)
- Flights from Cat Cay (CXY) to Cape Girardeau (CGI)
- Flights from Nantucket (ACK) to Cape Girardeau (CGI)
- Flights from Ithaca (ITH) to Cape Girardeau (CGI)
- Flights from Argostolion (EFL) to Cape Girardeau (CGI)
- Flights from Bellingham (BLI) to Cape Girardeau (CGI)
- Flights from Bartlesville (BVO) to Cape Girardeau (CGI)
- Flights from Grand Island (GRI) to Cape Girardeau (CGI)
- Flights from Fayetteville (FYV) to Cape Girardeau (CGI)
- Flights from Gary (GYY) to Cape Girardeau (CGI)