A calm body of water, a sandy beach, and a forested area in the distance.

Cape Girardeau Vacation Rentals

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Check prices for these dates

In two weeks
2 Oct - 4 Oct
In two months
13 Nov - 15 Nov
In three months
11 Dec - 13 Dec
In four months
8 Jan - 10 Jan

Our top choices for Cape Girardeau vacation rentals

Living area

1. Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (58 reviews)
"Great cute place. "
United States
Jeremy W.
The price is AED 298
AED 397 total
includes taxes & fees
21 Sep - 22 Sep
Little Blue Cottage on Spanish
Living area

2. Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals

Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
Cape Girardeau
The price is AED 337
AED 640 total
includes taxes & fees
20 Oct - 21 Oct
Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
1 bedroom, desk, iron/ironing board, WiFi

3. The Cottage, Rusted Route Farms

The Cottage, Rusted Route Farms
Jackson
10.0 out of 10, Exceptional, (3 reviews)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
The price is AED 459
AED 731 total
includes taxes & fees
21 Sep - 22 Sep
The Cottage, Rusted Route Farms
1 bedroom, WiFi (free), bed sheets

4. Purple Tiny House with Fire pit & Nature

Purple Tiny House with Fire pit & Nature
Cape Girardeau
The price is AED 456
AED 699 total
includes taxes & fees
21 Sep - 22 Sep
Purple Tiny House with Fire pit & Nature
Exterior

5. Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly

Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
Cape Girardeau
10.0 out of 10, Exceptional, (3 reviews)
"The house was very clean and Will kept and the whole property was well maintained. It was very comfortable and nicely decorated. The host was very responsive and helpful! Would definitely stay again and recommend."
United States
Sara C.
The price is AED 570
AED 834 total
includes taxes & fees
24 Sep - 25 Sep
Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
Coffee/tea maker, fridge, microwave, cookware/dishes/utensils

6. Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly

Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly
Cape Girardeau
The price is AED 551
AED 811 total
includes taxes & fees
21 Sep - 22 Sep
Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly
Exterior

7. The Little Cape Lofted Cottage | Creek & Nature

The Little Cape Lofted Cottage | Creek & Nature
Cape Girardeau
10.0 out of 10, Exceptional, (1 review)
"The tiny house was adorable, clean, and everything we expected. We can’t wait to stay in the others. We definitely recommend staying here. Lisa and Holly have done a wonderful job. Holly was great at getting back to me. Loved everything about our stay and the trip. Thank you so much"
United States
Kim K.
The price is AED 532
AED 790 total
includes taxes & fees
21 Sep - 22 Sep
The Little Cape Lofted Cottage | Creek & Nature
Exterior

8. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (44 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is AED 658
AED 1,158 total
includes taxes & fees
21 Sep - 22 Sep
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Smart TV, books

9. The Little Château | Woodland Escape

The Little Château | Woodland Escape
Cape Girardeau
The price is AED 570
AED 834 total
includes taxes & fees
27 Sep - 28 Sep
The Little Château | Woodland Escape
TV, fireplace

10. Gorgeous 1856 Log Cabin, Completely Renovated

Gorgeous 1856 Log Cabin, Completely Renovated
Jackson
10.0 out of 10, Exceptional, (6 reviews)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
The price is AED 735
AED 1,146 total
includes taxes & fees
21 Sep - 22 Sep
Gorgeous 1856 Log Cabin, Completely Renovated
Interior

11. The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse
Cape Girardeau
10.0 out of 10, Exceptional, (37 reviews)
"Amazing stay! Everything was perfect."
United States
Wayne F.
The price is AED 988
AED 1,497 total
includes taxes & fees
4 Oct - 5 Oct
The Twisted Sassafras Treehouse
Coffee/tea maker, fridge, microwave, dishwasher

12. Beautifully Renovated Farmhouse in Jackson, MO

Beautifully Renovated Farmhouse in Jackson, MO
Jackson
9.4 out of 10, Exceptional, (3 reviews)
" great stay,property landscape nicely manicured, quiet and relaxing inside and outside of the the dwelling."
United States
Sandy S.
The price is AED 735
AED 1,146 total
includes taxes & fees
21 Sep - 22 Sep
Beautifully Renovated Farmhouse in Jackson, MO
Pool

13. 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.8 out of 10, Exceptional, (11 reviews)
"Nice place, great times"
United States
Jace W.
The price is AED 1,157
AED 1,940 total
includes taxes & fees
21 Sep - 22 Sep
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Dining

14. Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (43 reviews)
"Super communication! . Accommodating. Nice people"
United States
JASEN
The price is AED 413
AED 516 total
includes taxes & fees
21 Sep - 22 Sep
Cozy cabins on beautiful Horseshoe Lake
Exterior

15. The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.4 out of 10, Exceptional, (31 reviews)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
The price is AED 413
AED 516 total
includes taxes & fees
21 Sep - 22 Sep
The Rested Duck Mallard Room
Interior

16. Cozy and Updated Farmhouse with King Suite

Cozy and Updated Farmhouse with King Suite
Anna
10.0 out of 10, Exceptional, (25 reviews)
"Comfortable bed which is what we needed. We weren’t there long but is was everything we needed."
United States
Kathy H.
The price is AED 327
AED 580 total
includes taxes & fees
30 Sep - 1 Oct
Cozy and Updated Farmhouse with King Suite
Property grounds

17. Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre
Dongola
10.0 out of 10, Exceptional, (106 reviews)
"Such a beautiful and peaceful place to stay Suzzie is a great host I stay there once or twice a year for the past several years loved every minute can’t wait to go back"
United States
Paul D.
The price is AED 496
AED 923 total
includes taxes & fees
21 Sep - 22 Sep
Charming cottage overlooking Lake Acre
Coffee/tea maker, fridge, microwave, oven

18. Relax in the country at Countryside Villas! - Villa A

Relax in the country at Countryside Villas! - Villa A
Jackson
10.0 out of 10, Exceptional, (37 reviews)
"Great place to stay, felt like home away from home. "
United States
Brittany
The price is AED 551
AED 663 total
includes taxes & fees
21 Sep - 22 Sep
Relax in the country at Countryside Villas! - Villa A
Interior

19. Villa B offers peace and quiet with beautiful views of the countryside.

Villa B offers peace and quiet with beautiful views of the countryside.
Jackson
9.8 out of 10, Exceptional, (14 reviews)
"We were only there for 1 night for a business trip but it was perfect for our stay. Very clean and comfortable and the host was onsite to welcome us. She even gave us a tip on the best place nearby for dinner that we will be going to any time we can in the future. I would gladly stay here again for future trips."
United States
Terry H.
The price is AED 551
AED 663 total
includes taxes & fees
21 Sep - 22 Sep
Villa B offers peace and quiet with beautiful views of the countryside.
Exterior

20. Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Anna
10.0 out of 10, Exceptional, (426 reviews)
"Cabin was cute and cozy!! "
United States
Anonymous traveler
The price is AED 430
AED 766 total
includes taxes & fees
24 Sep - 25 Sep
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau Hotel Reviews

The Riverview

The Riverview

8/10 Good
"Nice room and friendly staff. Everything was great except for the bathroom having a sliding door which provides less privacy. Also the mini refrigerator wasnt very cold even when on the coldest setting. Other than that zero complaints."
David 1-night trip
Posted 1 day ago
The Riverview

Frequently asked questions

Can I find vacation rentals in Cape Girardeau?

Yes, we offer vacation rentals in Cape Girardeau near Cape Splash Family Aquatic Center, or you can select a more remote option if you're looking for extra privacy while you relax. Visitors like the top-notch restaurants and shops in Cape Girardeau. Make sure you allow time to enjoy the riverfront during your vacation.

What are some of the best vacation home rentals in Cape Girardeau?

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau: This Cape Girardeau vacation home rental is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a fridge, and a stovetop. Some other homes for rent in Cape Girardeau include “Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau and Little Blue Cottage on Spanish.

How many vacation rentals will I find in Cape Girardeau?

Choose from 29 Expedia vacation rentals in Cape Girardeau for a memorable vacation.

What can I see and do in Cape Girardeau?

Family-friendly attractions include Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center, whereas Shawnee National Forest and Mississippi River are a couple of great spots to enjoy the outdoors. While here, Century Casino & Hotel Cape Girardeau and Show Me Center are other places worth a visit.

What are vacation rentals like in Cape Girardeau?

Vacation rentals are private properties you can book for a couple days or more in Cape Girardeau. Vacation rentals offer amenities such as hot tubs, fire pits, and patios so your stay will be comfortable. If you're concerned about cleanliness, vacation rentals can offer a sense of privacy away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for a small group gathering.