A calm body of water, a sandy beach, and a forested area in the distance.

Cape Girardeau Vacation Rentals

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Check prices for these dates

In two weeks
3 Jul - 5 Jul
In two months
14 Aug - 16 Aug
In three months
11 Sep - 13 Sep
In four months
9 Oct - 11 Oct

Our top choices for Cape Girardeau vacation rentals

Living area

Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very Good, (57 reviews)
"Great cute place. "
United States
Jeremy W.
The price is AED 298
AED 397 total
includes taxes & fees
25 Jun - 26 Jun
Little Blue Cottage on Spanish
Interior

Charming Secluded Getaway Cabin within minutes of amenities

Charming Secluded Getaway Cabin within minutes of amenities
Cape girardeau
10.0 out of 10, Exceptional, (22 reviews)
"Nice little Cabin in a beautiful area. Blair and her family were wonderful!"
United States
Keegan C.
The price is AED 569
AED 1,122 total
includes taxes & fees
25 Jun - 26 Jun
Charming Secluded Getaway Cabin within minutes of amenities
1 bedroom, desk, iron/ironing board, WiFi

The Cottage, Rusted Route Farms

The Cottage, Rusted Route Farms
Jackson
10.0 out of 10, Exceptional, (2 reviews)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
The price is AED 459
AED 716 total
includes taxes & fees
22 Jun - 23 Jun
The Cottage, Rusted Route Farms
Shower, hair dryer, towels, shampoo

Modern Boho Getaway · 1BR Apartment · By KeenStays

Modern Boho Getaway · 1BR Apartment · By KeenStays
Cape Girardeau
The price is AED 294
AED 614 total
includes taxes & fees
22 Jun - 23 Jun
Modern Boho Getaway · 1BR Apartment · By KeenStays
Outdoor dining

Studio Apt | King Bed, Full Kitchen · By KeenStays

Studio Apt | King Bed, Full Kitchen · By KeenStays
Cape Girardeau
The price is AED 294
AED 614 total
includes taxes & fees
30 Jun - 1 Jul
Studio Apt | King Bed, Full Kitchen · By KeenStays
Interior

The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse
Cape Girardeau
10.0 out of 10, Exceptional, (34 reviews)
"Nice, quiet, close to shopping & restaurants"
United States
Jaime M.
The price is AED 790
AED 1,154 total
includes taxes & fees
28 Jun - 29 Jun
The Twisted Sassafras Treehouse
TV, fireplace

Gorgeous 1856 Log Cabin, Completely Renovated

Gorgeous 1856 Log Cabin, Completely Renovated
Jackson
10.0 out of 10, Exceptional, (4 reviews)
"This was the coolest place! Our family absolutely loved it. Plenty of space, bathrooms, sitting areas outside were plenty as well as fireplaces and fire pit. The bedrooms are spacious- the area where the two twin beds are is downstairs and the beds are smaller but just know that going in. Beautiful area. We’d love to stay again."
United States
Victoria
The price is AED 735
AED 1,139 total
includes taxes & fees
29 Jun - 30 Jun
Gorgeous 1856 Log Cabin, Completely Renovated
Exterior

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (41 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is AED 731
AED 1,235 total
includes taxes & fees
14 Jul - 15 Jul
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Pool

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.6 out of 10, Exceptional, (9 reviews)
"Nice place, great times"
United States
Jace W.
The price is AED 1,377
AED 2,202 total
includes taxes & fees
14 Jul - 15 Jul
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Exterior

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Anna
10.0 out of 10, Exceptional, (413 reviews)
"Great location. Cozy cabin. Would stay there again. "
United States
jeffrey s
The price is AED 430
AED 728 total
includes taxes & fees
24 Jun - 25 Jun
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Exterior detail

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Makanda
9.8 out of 10, Exceptional, (66 reviews)
"Nice cabin. Location is great, near many wineries. Host was super friendly. We had no issues arise."
United States
James S.
The price is AED 378
AED 709 total
includes taxes & fees
6 Jul - 7 Jul
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Interior

Charming 2-bedroom with AC, WiFi in lovely Jonesboro

Charming 2-bedroom with AC, WiFi in lovely Jonesboro
Jonesboro
10.0 out of 10, Exceptional, (9 reviews)
"It was a beautiful building and just what my sister in law needed to stay at after a local event. "
United States
Heather C.
The price is AED 426
AED 946 total
includes taxes & fees
23 Jun - 24 Jun
Charming 2-bedroom with AC, WiFi in lovely Jonesboro
Exterior

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Makanda
9.8 out of 10, Exceptional, (48 reviews)
"Easily the best cabin experience I’ve ever had! Wonderful amenities everything we needed for a nice weekend stay was there and ready when we got there. Very comfortable space with plenty of room perfect destination for a small family get away will be returning soon thanks Steve!"
United States
Justin
The price is AED 441
AED 831 total
includes taxes & fees
29 Jun - 30 Jun
Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Interior

Cozy and Updated Farmhouse with King Suite

Cozy and Updated Farmhouse with King Suite
Anna
9.8 out of 10, Exceptional, (20 reviews)
"Nice little house that was perfect for our family of five plus our dog. We would stay here again if we found ourselves out this way again."
United States
Kyle
The price is AED 364
AED 619 total
includes taxes & fees
6 Jul - 7 Jul
Cozy and Updated Farmhouse with King Suite
Shower, towels, soap, shampoo

The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.4 out of 10, Exceptional, (31 reviews)
"It’s very nice and comfortable "
United States
John S.
The price is AED 413
AED 516 total
includes taxes & fees
22 Jun - 23 Jun
The Rested Duck Mallard Room
Dining

Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
10.0 out of 10, Exceptional, (41 reviews)
"Peaceful and suited our needs perfectly."
United States
Matthew
The price is AED 413
AED 516 total
includes taxes & fees
22 Jun - 23 Jun
Cozy cabins on beautiful Horseshoe Lake
Property grounds

Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre
Dongola
10.0 out of 10, Exceptional, (104 reviews)
"Enjoyed our stay great hospitality, everything we needed was addressed. We would highly recommend staying there. Great location "
United States
carlton h.
The price is AED 496
AED 1,032 total
includes taxes & fees
22 Jun - 23 Jun
Charming cottage overlooking Lake Acre
Smart TV

Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
9.8 out of 10, Exceptional, (28 reviews)
"Second time staying here. Will be back again."
United States
Ryan M.
The price is AED 413
AED 672 total
includes taxes & fees
22 Jun - 23 Jun
Peaceful secluded cabin located near Horseshoe Lake
Interior

Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!

Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!
Makanda
10.0 out of 10, Exceptional, (15 reviews)
"Great host, amenities, and location!"
United States
Kevin W.
The price is AED 452
AED 557 total
includes taxes & fees
2 Jul - 3 Jul
Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!
Terrace/patio

Contemporary Glamping with Native American Appeal

Contemporary Glamping with Native American Appeal
Anna
9.8 out of 10, Exceptional, (159 reviews)
"Everything was just as advertised. Perfect stay. "
United States
Jonathan P.
The price is AED 620
AED 1,179 total
includes taxes & fees
23 Jun - 24 Jun
Contemporary Glamping with Native American Appeal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau Hotel Reviews

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

10/10 Excellent
"Very nice, well run, well staffed, quiet yet and convenient location. Stairwells needed to be vacuumed and tidied, however, everything else was clean and maintained. Decent breakfast though food only tepid, and abundant parking provided. Though the shower enclosure leaks a bit, though shower is strong and is what hotel guests pray and thank God for afterwards when they stayover at a property. I anticipate repeating my stay in the future."
Timothy 2-night trip
Posted 1 hour ago
Tru By Hilton Cape Girardeau

Frequently asked questions

Can I find vacation rentals in Cape Girardeau?

Yes, we offer vacation rentals in Cape Girardeau near Cape Splash Family Aquatic Center, or you can select a more remote option if you're looking for extra privacy while you relax. Visitors like the top-notch restaurants and shops in Cape Girardeau. Make sure you allow time to enjoy the riverfront during your vacation.

What are some of the best vacation home rentals in Cape Girardeau?

Serenity South -- Gardens, River-Views, and Refreshing Space: This Cape Girardeau vacation home rental is located on a river and has a fireplace, a balcony, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. Some other homes for rent in Cape Girardeau include Little Blue Cottage on Spanish and “Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau.

How many vacation rentals will I find in Cape Girardeau?

Choose from 25 Expedia vacation rentals in Cape Girardeau for a memorable vacation.

What can I see and do in Cape Girardeau?

Family-friendly attractions include Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center, whereas Shawnee National Forest and Mississippi River are a couple of great spots to enjoy the outdoors. While here, Century Casino & Hotel Cape Girardeau and Hunter Valley Winery are other places worth a visit.

What are vacation rentals like in Cape Girardeau?

Vacation rentals are private properties you can book for a couple days or more in Cape Girardeau. Vacation rentals offer amenities such as hot tubs, fire pits, and patios so your stay will be comfortable. If you're concerned about cleanliness, vacation rentals can offer a sense of privacy away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for a small group gathering.