Charleston Vacation Rentals from AED 297: Search Short-Term Rentals

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Our top choices for Charleston vacation rentals

A cozy room with a wooden table and chairs, a large window, and a door with a sign.

1. Cozy cabins on beautiful Horseshoe Lake

Olive Branch

JASEN

AED 485 total

includes taxes & fees

12 Nov - 13 Nov

A loft-style room with a wooden interior, a sofa, a table with a pumpkin decoration, and a staircase leading to an upper level.

2. Peaceful secluded cabin located near Horseshoe Lake

Miller City

George B.

AED 763 total

includes taxes & fees

15 Nov - 16 Nov

A small, single-story building with a wooden exterior and large windows.

3. The Rested Duck Mallard Room

Olive Branch

mike b.

AED 485 total

includes taxes & fees

12 Nov - 13 Nov

A living room with a TV, a fireplace, a sofa, and wall art.

4. Little Blue Cottage on Spanish

Cape Girardeau

Jeremy W.

AED 368 total

includes taxes & fees

14 Nov - 15 Nov

A modern kitchen with white cabinetry, stainless steel appliances, and a window with a view of greenery.

5. Quiet Country Stay: Modern Home Near Paducah

Cunningham

AED 1,067 total

includes taxes & fees

23 Nov - 24 Nov

An aerial view of a river surrounded by dense forest, with a small house near the water's edge.

6. Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

Villa Ridge

Michelle U.

AED 888 total

includes taxes & fees

22 Nov - 23 Nov

A modern kitchen with a built-in microwave, stainless steel appliances, and a sink.

7. Charming Home just minutes from Interstate and Mall

Kevil

Deannena H.

AED 692 total

includes taxes & fees

22 Nov - 23 Nov

A single-story house with a gabled roof, a front porch with two chairs, and a front door with a decorative glass panel.

8. Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

New Madrid

Jessica S.

AED 1,299 total

includes taxes & fees

12 Nov - 13 Nov

A kitchen with grey cabinets, a stainless steel dishwasher, a microwave, and an oven.

9. Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals

Cape Girardeau

AED 654 total

includes taxes & fees

16 Nov - 17 Nov

A two-story house with a front porch, a small garden, and a white picket fence.

10. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Cape Girardeau

Pynktoria !.

AED 1,103 total

includes taxes & fees

15 Nov - 16 Nov

11. Quiet Country Stay: Modern Home Near Paducah

Cunningham

Sheila C.

AED 1,038 total

includes taxes & fees

23 Nov - 24 Nov

A covered outdoor seating area with stone flooring and chairs, a stone pathway, and a wooden structure.

12. Vacation rental attached to our house out in the country.

Union City

Sherrie S.

AED 566 total

includes taxes & fees

12 Nov - 13 Nov

A house with a backyard swimming pool, outdoor furniture, and a barbecue area.

13. 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Cape Girardeau

Jace W.

AED 2,034 total

includes taxes & fees

12 Nov - 13 Nov

A hot tub in an outdoor setting with a wooden deck and lounge chairs.

14. Perfect Couples Retreat - firepit

Carlisle County

Russell

AED 676 total

includes taxes & fees

28 Nov - 29 Nov

A hot tub with a wooden deck and outdoor seating area.

15. The Roost | Hot Tub, Ponds & Farm Views

Carlisle County

AED 740 total

includes taxes & fees

12 Nov - 13 Nov

View all properties

Find vacation rentals that suit your style

Top Charleston Hotel Reviews

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

Drury Inn & Suites Sikeston, MO

Sikeston

10/10 Excellent

Judy

A conference room with a long table, multiple chairs, and a television screen on the wall.

Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

10/10 Excellent

Anonymous traveler

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

Drury Inn & Suites Cape Girardeau

Cape Girardeau

10/10 Excellent

StephM

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

Best Western Plus Sikeston I-55

Sikeston

10/10 Excellent

Anonymous traveler

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

10/10 Excellent

Kristin

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

10/10 Excellent

JACK OR JULIE

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

10/10 Excellent

Britney

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

Pear Tree Inn Cape Girardeau West

Cape Girardeau

10/10 Excellent

Kimberly

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

10/10 Excellent

Anonymous traveler

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

10/10 Excellent

Kelly

A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

Comfort Inn & Suites Sikeston I-55

Sikeston

10/10 Excellent

This is a fantastic hotel! The staff is very wonderful and helpful and thoughtful when my father passed away in November of 2017, part of my family stayed at this hotel. Now I am back here waiting for my mother to arrive for we are going to finally get to see my father who was a Vietnam veteran and was buried at the Bloomfield Cemetery has his headstone put up anyhow I have had some difficulties with a lot of the hotels around here in this one is by far the best I would recommend it to anyone.

Anonymous traveler

Frequently Asked Questions

Can I find a vacation rental in Charleston?

Yes, we have vacation rentals close to the most popular sights in Charleston, or you can go with a secluded option if you want a relaxing place to stay. Our travelers say Charleston has a good selection of restaurants. Make sure you have time to check out the entertainment choices and theaters during your trip.

What are some of the best vacation rentals that Charleston has to offer?

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau: Visitors like this Charleston vacation home rental. It is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a fridge, and a stovetop.

What can I see and do in Charleston?

Mississippi River and Ohio River are a couple of lovely local spots to get outside and enjoy nature. Ballard Wildlife Management Area and Columbus-Belmont State Park are a couple of places you'll find in the larger area.

What are vacation rentals like in Charleston?

Vacation rentals are private accommodations you can book for a few days or a quick weekend in Charleston. Vacation rentals feature extras like WiFi and washers and dryers so you'll feel just like you're at home. If you're concerned about a sanitized environment, vacation rentals can offer a sense of security away from shared hotel elevators and bustling concierge desks while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which makes a vacation rental a great choice for family trips.

Charleston Vacation Rentals

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Charleston vacation rentals

1. Cozy cabins on beautiful Horseshoe Lake

2. Peaceful secluded cabin located near Horseshoe Lake

3. The Rested Duck Mallard Room

4. Little Blue Cottage on Spanish

5. Quiet Country Stay: Modern Home Near Paducah

6. Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

7. Charming Home just minutes from Interstate and Mall

8. Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

9. Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals

10. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

11. Quiet Country Stay: Modern Home Near Paducah

12. Vacation rental attached to our house out in the country.

13. 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

14. Perfect Couples Retreat - firepit

15. The Roost | Hot Tub, Ponds & Farm Views

Find vacation rentals that suit your style

Top Charleston Hotel Reviews

Drury Inn & Suites Sikeston, MO

10/10 Excellent

Frequently Asked Questions

Can I find a vacation rental in Charleston?

What are some of the best vacation rentals that Charleston has to offer?

What can I see and do in Charleston?

What are vacation rentals like in Charleston?