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Comfort Inn & Suites Sikeston I-55

2.5 star property
Travelers find productivity and relaxation at this convenient hotel, where the indoor pool offers a refreshing break after meetings or sightseeing

Choose dates to view prices

Just off I-55, Comfort Inn & Suites Sikeston I-55 provides a practical base for travelers. Guests can swim in the indoor pool, use the laundry facilities, connect with in-room WiFi, maintain fitness routines at the gym, or handle work matters in the business center.

Reviews

8.4 out of 10
Very good

Popular amenities

  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Gym
The current price is AED 323
AED 368 total
includes taxes & fees
15 Mar - 16 Mar

Room options

Available filters for rooms
Showing 5 of 5 rooms

View all photos for Standard Room, 2 Queen Beds, Non Smoking

Standard Room, 2 Queen Beds, Non Smoking | Desk, free WiFi, bed sheets, alarm clocks

Standard Room, 2 Queen Beds, Non Smoking

8.0 out of 10
Very good
(11 reviews)

Highlights

Air conditioning
Refrigerator
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking

Suite, 1 King Bed with Sofa bed, Non Smoking | Desk, free WiFi, bed sheets, alarm clocks

Suite, 1 King Bed with Sofa bed, Non Smoking

Highlights

Air conditioning
Refrigerator
Sofa bed
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Room, 1 King Bed, Accessible, Non Smoking

Room, 1 King Bed, Accessible, Non Smoking | Desk, free WiFi, bed sheets, alarm clocks

Room, 1 King Bed, Accessible, Non Smoking

8.6 out of 10
Excellent
(4 reviews)

Highlights

Air conditioning
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 2 Queen Beds, Accessible, Non Smoking

Room, 2 Queen Beds, Accessible, Non Smoking | Desk, free WiFi, bed sheets, alarm clocks

Room, 2 Queen Beds, Accessible, Non Smoking

10.0 out of 10
Exceptional
(4 reviews)

Highlights

Air conditioning
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 4
  • 2 Queen Beds

View all photos for Standard Room, 1 King Bed, Non Smoking

Standard Room, 1 King Bed, Non Smoking | Desk, free WiFi, bed sheets, alarm clocks

Standard Room, 1 King Bed, Non Smoking

8.0 out of 10
Very good
(14 reviews)

Highlights

Air conditioning
Refrigerator
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

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Free daily full breakfast

Best Western Plus Sikeston I-55

Sikeston
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
8.4 out of 10, Very Good, 1,005 reviews
The price is AED 300
AED 342 total
includes taxes & fees
26 Mar - 27 Mar
Best Western Plus Sikeston I-55

About the neighborhood

Sikeston is home to Comfort Inn & Suites Sikeston I-55. The area's natural beauty can be seen at Mississippi River and Central Park, while Sikeston Depot Museum and Front Street Studio & Art Gallery are cultural highlights. Visit our Sikeston travel guide
Map
109 Matthews Ln, Sikeston, MO, 63801

What's nearby

  • Panorama of Academic Hall, Southeast Missouri State University
    Southeast Missouri State University
    33 min drive - 62.0 km
  • City of Miner Convention Center
    5 min walk - 0.4 km
  • Central Park
    5 min drive - 4.8 km
  • Saint Francis Medical Center
    28 min drive - 57.8 km
  • Isle Casino Cape Girardeau
    33 min drive - 61.2 km

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    29 min drive

Restaurants

  • Lambert's Cafe
    17 min walk
  • Buffalo Wild Wings
    5 min drive
  • Burger King
    4 min drive
  • Starbucks
    6 min drive
  • Imo's Pizza
    6 min drive

About this property

Comfort Inn & Suites Sikeston I-55

Property highlights
Take advantage of laundry facilities, a gym, and a business center at Comfort Inn & Suites Sikeston I-55. Stay connected with free in-room WiFi.
Other perks include:
  • An indoor pool
  • Free self parking
  • Laundry services, an elevator, and a front-desk safe
  • A 24-hour front desk
  • Guest reviews give top marks for the helpful staff
Room features
All 64 rooms feature comforts such as air conditioning, in addition to amenities like free WiFi.
Other amenities include:
  • Bathrooms with tubs or showers
  • Cable channels, coffee/tea makers, and desks

Similar properties

Free daily full breakfast
Best Western Plus Sikeston I-55
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
8.4 out of 10, Very Good, 1,005 reviews
The price is AED 300
AED 342 total
includes taxes & fees
26 Mar - 27 Mar
Best Western Plus Sikeston I-55
Compare similar properties

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking available

Things to do

  • Gym
  • Indoor pool

Family friendly

  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Laundry facilities
  • Safe at front desk

Business services

  • Business center

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible registration desk

More

  • 3 floors
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided

Bathroom

  • Bathtub or shower
  • Private bathroom
  • Towels provided

Entertainment

  • Cable/satellite channels

Food and drink

  • Coffee/tea maker

More

  • Air conditioning
  • Desk
  • Phone

Policies

Check-in

Check-in start time: 2:00 PM; Check-in end time: anytime
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 20 per pet, per night
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total (up to 20 lbs per pet)
Specific rooms only; pet-friendly rooms can be requested by contacting the property at the number on the booking confirmation

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

Optional extras

  • Pet fee: USD 20 per pet, per night
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)

Property is also known as

Comfort Inn Sikeston Hotel
Comfort Inn Sikeston

Frequently asked questions

Does Comfort Inn & Suites Sikeston I-55 have a pool?

Yes, this property has an indoor pool.

How much does it cost to stay at Comfort Inn & Suites Sikeston I-55?

As of 8 March 2026, prices found for a 1-night stay for 2 adults at Comfort Inn & Suites Sikeston I-55 on 15 March 2026 start from AED 323, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is Comfort Inn & Suites Sikeston I-55 pet-friendly?

Yes, Comfort Inn & Suites Sikeston I-55 allows cats and dogs (limit 2 total) with a maximum weight of up to 20 lbs per pet. There's a fee of USD 20 per pet, per night. Service animals are exempt from fees.

How much is parking?

Self parking is free at this property.

What time is check-in at Comfort Inn & Suites Sikeston I-55?

Check-in start time: 2:00 PM; Check-in end time: anytime.

What time is check-out at Comfort Inn & Suites Sikeston I-55?

Check-out is at 11:00 AM.

Where is Comfort Inn & Suites Sikeston I-55 located?

Situated in Sikeston, this hotel is 0.4 mi (0.6 km) from City of Miner Convention Center and within 6 mi (10 km) of Sikeston Depot Museum and Central Park. Front Street Studio & Art Gallery is 9 mi (14.5 km) away.

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Reviews

Comfort Inn & Suites Sikeston I-55 Reviews

8.4

Very Good

8.6

Cleanliness

8.6

Location

8.8

Staff & service

8.2

Property conditions & facilities
Rating 10 - Excellent. 137 out of 288 reviews
Rating 8 - Good. 94 out of 288 reviews
Rating 6 - Okay. 29 out of 288 reviews
Rating 4 - Poor. 19 out of 288 reviews
Rating 2 - Terrible. 9 out of 288 reviews

Reviews

10/10 Excellent

aileen

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The hotel was very clean, beds were comfortable, and staff was friendly and helpful.
Stayed 1 night in Dec 2025

10/10 Excellent

Connie

Liked: Cleanliness, property conditions & facilities
Room was clean, breakfast was very good.
Stayed 1 night in Nov 2025

10/10 Excellent

Lisa

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
It was a very nice stay. The pool was clean and enjoying!
Stayed 1 night in Jul 2025

8/10 Good

Amanda

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice hotel with great staff. Room was fine, breakfast could be better but overall a good stay for this area.

10/10 Excellent

Kimberly

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We were in town for a pit-stop to sleep and the staff was very nice. Comfy beds and nice location
Stayed 1 night in Mar 2025

10/10 Excellent

Peggy

Liked: Cleanliness, staff & service, property conditions & facilities
The facility was very nice.
Stayed 2 nights in May 2025

8/10 Good

Denise

hotel was fine clean and convient
Stayed 1 night in Feb 2025

8/10 Good

John

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Good stay

It was decent…slept well The room was clean
Stayed 1 night in May 2025

10/10 Excellent

Tammi

Liked: Cleanliness, staff & service, property conditions & facilities
Very clean, nice staff and good breakfast
Stayed 1 night in Aug 2023

10/10 Excellent

John

Liked: Cleanliness, staff & service, property conditions & facilities
Great for overnights, staff friendly and attentive
Stayed 1 night in Apr 2024

8/10 Good

Dylan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Right off the main drag, huge complimentary breakfast area
Stayed 1 night in May 2024

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, property conditions & facilities
Conveniant to I55, clean, and comfortable,
Stayed 1 night in Dec 2024

10/10 Excellent

Roger

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice spacious rooms. Beds were very comfortable. Quiet place.
Stayed 1 night in Jan 2025

10/10 Excellent

Drew

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Perfect Pit Stop

Check in was easy with friendly staff. Hotel had everything you would need, plus walking distance to dining.
Stayed 1 night in Sep 2024

10/10 Excellent

Mark

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room carpet could use changing, but otherwise clean, quiet, feiendly staff, and a great morning breakfast.
Stayed 1 night in Sep 2024

10/10 Excellent

Timothy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean & friendly service. Easy access from the highway. Bed is comfortable. Breakfast area looks very nice. A good selection of food choices. Would recommend this property. The ice machine wasn’t working on our floor, but could get ice near the lobby, so not a huge issue.
Stayed 1 night in May 2025

8/10 Good

JOHN

Liked: Property conditions & facilities
Seems like clean well kept property!
Stayed 1 night in May 2024

10/10 Excellent

Susan

Liked: Cleanliness, staff & service, property conditions & facilities
Check in was quick and easy. Very courteous and professional staff.
Stayed 1 night in Mar 2024

10/10 Excellent

Diane

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice helpful young man checked us in. And help with our TV connection!
Stayed 1 night in Feb 2025

8/10 Good

Verified traveler

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Just one night

We were in town for a funeral and to visit family. We were only at the hotel for a place to sleep. It was comfortable, quiet, and clean. Plus, it was very affordable.
Stayed 1 night in Nov 2024

8/10 Good

Latrisha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very good customer service. Rooms were worth the price.
Stayed 2 nights in May 2024

10/10 Excellent

Gail

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
our room was clean and well kept.
Stayed 1 night in May 2024

10/10 Excellent

Tina

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was very easy to get to and easy on the highway. Clean. Check in was awesome. I would definitely stay here again.
Stayed 1 night in Sep 2023

10/10 Excellent

Marsha

Liked: Property conditions & facilities
Very clean! Bed and pillows comfortable. Pool and hot tub was nice. They had plenty of pool towels. Breakfast was okay. They had the normal breakfast but the eggs and sausage was fake. The waffles never disappoint. McDonald’s right next store if you want. Very impressed with this place. Would definitely recommend.
Stayed 1 night in Mar 2025

8/10 Good

Amelia

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean and modern. Friendly helpful staff. Needs more visible security like cameras and a safe in the rooms. Also real eggs not microwave bags, would be nice, but overall a decent breakfast.
Stayed 1 night in Jul 2024