Sikeston, MO

Travel Guide

A tree with sunlight filtering through its leaves, creating a warm glow.
A person walking through a cornfield.
A building with three tall chimneys, surrounded by blooming trees with pink and white flowers.
A sign for Lambert's, a place of worship.
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
The price is AED 345 per night from Nov 8 to Nov 9
AED 345
AED 397 total
8 Nov - 9 Nov
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
The price is AED 244 per night from Nov 5 to Nov 6
AED 244
AED 278 total
5 Nov - 6 Nov
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Days Inn and Suites by Wyndham Sikeston
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
The price is AED 353 per night from Nov 22 to Nov 23
AED 353
AED 401 total
22 Nov - 23 Nov
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
Hampton Inn Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Anna IL
Stay at this cabin in Anna. Enjoy a garden, patios, and cable/satellite TV service. Our guests praise the helpful staff and the property condition in our reviews. ...
10/10 Exceptional! (431 reviews)
"Very nice and clean"

Reviewed on 14 October 2026

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
3  Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

Makanda IL
Book a stay at this golf cabin in Makanda. Enjoy free WiFi, a garden, and patios. Popular attractions Stone Creek Golf Club and Resort and Makanda Boardwalk ...
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

Cape Girardeau MO
Stay at this vacation home in Cape Girardeau. Enjoy free WiFi, laundry facilities, and an in-room coffeemaker. Popular attractions Show Me Center and Century ...
9.8/10 Exceptional! (39 reviews)
"Great location. Clean house with plenty of fresh linens"

Reviewed on 29 October 2026

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Sikeston attractions

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