Photo by Jessica King

Find Family Hotels in De Soto, MO

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Pick from 1 De Soto Family Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

"When we walked in the lodge it was spotless. Very homey and clean. The staff was so kind. We will definitely be back."

AED 732 total

includes taxes & fees

9 Jun - 10 Jun

Frequently asked questions

What's De Soto like for family-friendly vacations?

The destination of De Soto is a great choice if you’ve been thinking about a vacation with your kids. The restaurants here makes this an attractive vacation spot for families. Arrange a flight into St. Louis, MO (SUS-Spirit of St. Louis), which is located 36.5 mi (58.8 km) from the city center.

When's the best time to book a family-friendly vacation in De Soto?

The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for De Soto is 46 inches.

What's there to see and do with your family in De Soto?

While you are visiting De Soto, you might want to round up the kiddos and make time to see interesting attractions such as Washington State Park, St. Francois State Park, and Bonne Terre Mine. Make sure you have lots of time for activities like Big River and St. Joe State Park.