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Find Family Hotels in De Soto, MO

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Check availability on De Soto Family Hotels

Tonight
3 Dec - 4 Dec
Tomorrow
4 Dec - 5 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top De Soto Family Hotels

Exterior
Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington

2.0 star property
Farmington
8.0 out of 10, Very Good, (610)
"Clean, friendly staff, quiet"
United States
Stacy
The price is AED 203
AED 231 total
includes taxes & fees
5 Dec - 6 Dec
Super 8 by Wyndham Farmington
Business center
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 star property
Farmington
8.0 out of 10, Very Good, (1003)
"Room was clean and big. Breakfast was awesome!"
United States
Ashley
The price is AED 200
AED 227 total
includes taxes & fees
10 Dec - 11 Dec
Baymont Inn and Suites by Wyndham Farmington, MO
Lobby sitting area
Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South

2.5 star property
Festus
7.8 out of 10, Good, (906)
"Vary clean"
United States
George
The price is AED 297
AED 347 total
includes taxes & fees
1 Jan - 2 January 2026
Comfort Inn Festus - St Louis South
Free daily buffet breakfast
Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG

2.5 star property
Farmington
8.6 out of 10, Excellent, (412)
"The staff was great!"
United States
Christopher
The price is AED 294
AED 917 total
includes taxes & fees
12 Dec - 13 Dec
Holiday Inn Express & Suites Farmington by IHG
2 bedrooms, WiFi, bed sheets
The Lux- Cozy 2-bedroom apartment with AC and WiFi in enjoyable Bonne Terre

The Lux- Cozy 2-bedroom apartment with AC and WiFi in enjoyable Bonne Terre

Bonne Terre
9.2 out of 10, Wonderful, (17)
"Really nice and enjoyable....would stay again"
United States
mark n.
The price is AED 165
AED 603 total
includes taxes & fees
7 Dec - 8 Dec
The Lux- Cozy 2-bedroom apartment with AC and WiFi in enjoyable Bonne Terre
Exterior
Hampton Inn Farmington

Hampton Inn Farmington

2.5 star property
Farmington
8.8 out of 10, Excellent, (517)
"Clean room, friendly staff."
United States
William
The price is AED 379
AED 432 total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn Farmington
Premium bedding, desk, iron/ironing board, free cribs/infant beds
Quality Inn Farmington

Quality Inn Farmington

2.5 star property
Farmington
7.6 out of 10, Good, (858)
"We loved it and we are still staying "
United States
Dustin
The price is AED 187
AED 224 total
includes taxes & fees
21 Dec - 22 Dec
Quality Inn Farmington
Property grounds
Peter Ray House

Peter Ray House

Maeystown
10.0 out of 10, Exceptional, (70)
"The house was wonderful, the town was delightful, and the people were very friendly! We can’t wait for our next trip!"
United States
Deborah
The price is AED 496
AED 821 total
includes taxes & fees
4 Dec - 5 Dec
Peter Ray House
Children's area
Adorable small house - quiet & safe - 2 BR 1 Bath

Adorable small house - quiet & safe - 2 BR 1 Bath

Imperial
9.4 out of 10, Exceptional, (13)
"Great place for a short get away"
United States
andytrower U.
The price is AED 396
AED 759 total
includes taxes & fees
8 Dec - 9 Dec
Adorable small house - quiet & safe - 2 BR 1 Bath
Fridge, microwave, oven, stovetop
The Shack- 3 bedroom finished house

The Shack- 3 bedroom finished house

Leadwood
8.6 out of 10, Excellent, (9)
"Was pretty clean and overall enjoyed our stay"
United States
Nicole V.
The price is AED 195
AED 673 total
includes taxes & fees
6 Dec - 7 Dec
The Shack- 3 bedroom finished house
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top De Soto Hotel Reviews

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

10/10 Excellent
"Was very good stay"
A 2-night trip
Posted 19 hours ago
Baymont Inn and Suites by Wyndham Farmington, MO

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Frequently asked questions

What's De Soto like for family-friendly vacations?
The destination of De Soto is a great choice if you've been thinking about a vacation with your kids. The restaurants here makes this an attractive vacation spot for families. Arrange a flight into St. Louis, MO (SUS-Spirit of St. Louis), which is located 36.5 mi (58.8 km) from the city center.
When's the best time to book a family-friendly vacation in De Soto?
The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for De Soto is 46 inches.
What's there to see and do with your family in De Soto?
While you are visiting De Soto, you might want to round up the kiddos and make time to see interesting attractions such as Redfield's Flea Market, Bonne Terre Mine, and Festus Public Library. Make sure you have lots of time for activities like Sunrise Lake Beach and Big River.