Photo by Jessica King

Find Family Hotels in De Soto, MO

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on De Soto Family Hotels

Tonight
4 Oct - 5 Oct
Tomorrow
5 Oct - 6 Oct
Next weekend
10 Oct - 12 Oct
In two weeks
17 Oct - 19 Oct

Top De Soto Family Hotels

Pear Tree Inn St. Louis Arnold
Lobby

Pear Tree Inn St. Louis Arnold

2.5 star property
9.2 out of 10, Wonderful, (1002)
"Clean, comfortable and pleasant stay."
The price is AED 331
AED 382 total
includes taxes & fees
13 Oct - 14 Oct
Pear Tree Inn St. Louis Arnold
Baymont Inn and Suites by Wyndham Farmington, MO
Business center

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 star property
8.0 out of 10, Very Good, (1003)
"Great location"
The price is AED 197
AED 224 total
includes taxes & fees
26 Oct - 27 Oct
Baymont Inn and Suites by Wyndham Farmington, MO
Super 8 by Wyndham Farmington
Exterior

Super 8 by Wyndham Farmington

2.0 star property
8.0 out of 10, Very Good, (590)
"Clean, friendly staff, quiet"
The price is AED 219
AED 249 total
includes taxes & fees
12 Oct - 13 Oct
Super 8 by Wyndham Farmington
Holiday Inn Express & Suites Farmington by IHG
Free daily buffet breakfast

Holiday Inn Express & Suites Farmington by IHG

2.5 star property
8.6 out of 10, Excellent, (409)
"Great hotel"
The price is AED 345
AED 978 total
includes taxes & fees
2 Nov - 3 Nov
Holiday Inn Express & Suites Farmington by IHG
Clifford's Country Cottage
Fridge, microwave, oven, stovetop

Clifford's Country Cottage

2.5 star property
9.8 out of 10, Exceptional, (20)
"Great place to stayLove the interiorPerfect set up for what we needed"
The price is AED 459
AED 560 total
includes taxes & fees
7 Oct - 8 Oct
Clifford's Country Cottage
Comfort Inn Festus - St Louis South
Lobby sitting area

Comfort Inn Festus - St Louis South

2.5 star property
8.0 out of 10, Very Good, (887)
"The stay and food "
The price is AED 299
AED 349 total
includes taxes & fees
2 Nov - 3 Nov
Comfort Inn Festus - St Louis South
Newly remodeled house minutes away from downtown, golf courses + BIG back yard
Children's area

Newly remodeled house minutes away from downtown, golf courses + BIG back yard

2.0 star property
9.8 out of 10, Exceptional, (18)
"This property worked well for our needs. Very convenient location to gas, food and golf course. "
The price is AED 481
AED 921 total
includes taxes & fees
3 Nov - 4 Nov
Newly remodeled house minutes away from downtown, golf courses + BIG back yard
The Lux- Cozy 2-bedroom apartment with AC and WiFi in enjoyable Bonne Terre
2 bedrooms, WiFi, bed sheets

The Lux- Cozy 2-bedroom apartment with AC and WiFi in enjoyable Bonne Terre

9.2 out of 10, Wonderful, (17)
"We had a plesent stay, there were also extra ementitys like coffee, it was very clenly and well handeld "
The price is AED 208
AED 649 total
includes taxes & fees
6 Oct - 7 Oct
The Lux- Cozy 2-bedroom apartment with AC and WiFi in enjoyable Bonne Terre
Drury Inn & Suites St. Louis Arnold
Restaurant

Drury Inn & Suites St. Louis Arnold

3.0 star property
9.6 out of 10, Exceptional, (1000)
"The hotel staff was very helpful and friendly. The breakfast and dinner were an awesome treat."
The price is AED 411
AED 476 total
includes taxes & fees
2 Nov - 3 Nov
Drury Inn & Suites St. Louis Arnold
Hampton Inn Farmington
Exterior

Hampton Inn Farmington

2.5 star property
8.8 out of 10, Excellent, (504)
"Had a very nice stay!"
The price is AED 546
AED 622 total
includes taxes & fees
2 Nov - 3 Nov
Hampton Inn Farmington
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top De Soto Hotel Reviews

Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold

10/10 Excellent
"The hotel staff was very helpful and friendly. The breakfast and dinner were an awesome treat."
Diana 2-night trip
Posted 4 days ago
Drury Inn & Suites St. Louis Arnold

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's De Soto like for family-friendly vacations?
The destination of De Soto is a great choice if you've been thinking about a vacation with your kids. The restaurants here makes this an attractive vacation spot for families. Arrange a flight into St. Louis, MO (SUS-Spirit of St. Louis), which is located 36.5 mi (58.8 km) from the city center.
When's the best time to book a family-friendly vacation in De Soto?
The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for De Soto is 46 inches.
What's there to see and do with your family in De Soto?
While you are visiting De Soto, you might want to round up the kiddos and make time to see interesting attractions such as Redfield's Flea Market, Bonne Terre Mine, and Festus Public Library. Make sure you have lots of time for activities like Sunrise Lake Beach and Big River.