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Apartments in Defiance

Sunny SparkingClean King bed Apt- CreveCoeurPark

9.6 out of 10, Exceptional, (10)
"Good Stay"
Sunny SparkingClean King bed Apt- CreveCoeurPark

Free Breakfast + Pool, Gym, and BBQ Area! Studio Suite Perfect for Business Travelers

Free Breakfast + Pool, Gym, and BBQ Area! Studio Suite Perfect for Business Travelers

Studio | Lovely Suite Close to Edward Jones!

Studio | Lovely Suite Close to Edward Jones!

Great for Business Travelers! Studio Suite Near Edward Jones! Shared Pool + Free Breakfast!

9.6 out of 10, Exceptional, (4)
"We loved the room, property, and location. Super clean and relaxing. Great breakfast in the morning. Perfect for a weekend getaway!"
Great for Business Travelers! Studio Suite Near Edward Jones! Shared Pool + Free Breakfast!

Main Street Balcony Apartment by StayLage!

9.4 out of 10, Exceptional, (30)
"Enjoyed staying here"
The price is AED 595
AED 1,796 total
includes taxes & fees
22 Jun - 23 Jun
Main Street Balcony Apartment by StayLage!

Prime Loft of Main Street

9.8 out of 10, Exceptional, (88)
"Fantastic place and location!"
The price is AED 426
AED 908 total
includes taxes & fees
17 Jun - 18 Jun
Prime Loft of Main Street

The Lofts of North Main Street

9.6 out of 10, Exceptional, (138)
"This is our 2nd time staying here for a girls weekend, and it is perfect."
The price is AED 426
AED 908 total
includes taxes & fees
17 Jun - 18 Jun
The Lofts of North Main Street

Amazing Renovated Historic Loft on Main Street

10.0 out of 10, Exceptional, (52)
"The place was great, just as advertised. Location was close to everything and made for a nice weekend away from kids"
The price is AED 426
AED 908 total
includes taxes & fees
17 Jun - 18 Jun
Amazing Renovated Historic Loft on Main Street

Studio on Historic Main by StayLage

9.2 out of 10, Wonderful, (24)
"A great location and close to the Katy Trail."
The price is AED 357
AED 872 total
includes taxes & fees
17 Jun - 18 Jun
Studio on Historic Main by StayLage

The Historic Bricks on Main

9.6 out of 10, Exceptional, (10)
"Loved the property and location. Able to walk to all the shops, restaurants, bars etc. "
The price is AED 377
AED 875 total
includes taxes & fees
24 Jun - 25 Jun
The Historic Bricks on Main

Main Street Living! 2 Bedroom Unit right On Main!

10.0 out of 10, Exceptional, (26)
"Perfect location. Very clean. Would highly recommend!"
Main Street Living! 2 Bedroom Unit right On Main!

Duplex Hideaway in St. Charles, MO

10.0 out of 10, Exceptional, (4)
"Good location, comfortable bed, new interior, well equipped. Very clean and organized!"
The price is AED 416
AED 1,034 total
includes taxes & fees
17 Jun - 18 Jun
Duplex Hideaway in St. Charles, MO

Charming Duplex on Main

10.0 out of 10, Exceptional, (12)
"Everything was awesome!!!!!!"
Charming Duplex on Main

Spacious 2-Bedroom Near Main St by StayLage

8.6 out of 10, Excellent, (12)
"We are grateful for our comfortable stay, and the location felt safe as well as close to everything."
The price is AED 381
AED 1,038 total
includes taxes & fees
22 Jun - 23 Jun
Spacious 2-Bedroom Near Main St by StayLage

Private Basement Retreat w/ HOT TUB by StayLage

9.0 out of 10, Wonderful, (7)
"It is absolutely beautiful. The room is huge it's super clean the hot tub was so nice the little back patio is stunning we spent our honeymoon here and 10 out of 10 recommend here "
The price is AED 337
AED 960 total
includes taxes & fees
17 Jun - 18 Jun
Private Basement Retreat w/ HOT TUB by StayLage

Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

2.0 star property
8.6 out of 10, Excellent, (13)
"The property was quiet and as expected. They were incredibly responsive and helpful with everything. "
The price is AED 248
AED 505 total
includes taxes & fees
25 Jun - 26 Jun
Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

Great for Business Travelers! Pool + Gym

The price is AED 526
AED 698 total
includes taxes & fees
29 Jun - 30 Jun
Great for Business Travelers! Pool + Gym

Cozy country setting 4 miles from route 66

10.0 out of 10, Exceptional, (6)
"Really nice property! Country setting and nice big living area."
The price is AED 551
AED 861 total
includes taxes & fees
17 Jun - 18 Jun
Cozy country setting 4 miles from route 66

The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail

8.0 out of 10, Very Good, (3)
"The unit was clean and comfortable, and easy to get in and out. Cooking was possible with a full setup kitchen, but there was also restaurants nearby as well. The host was responsive and took quick action on a small issue. I'd recommend this place for anyone wanting to visit the Katy trail."
The price is AED 848
AED 1,490 total
includes taxes & fees
17 Jun - 18 Jun
The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail

Back Door Guest Suit, charming downtown area, 2 minute walk to Missouri River.

10.0 out of 10, Exceptional, (4)
"Beautiful relaxing place in adorable neighborhood! Quite the find!"
The price is AED 459
AED 808 total
includes taxes & fees
17 Jun - 18 Jun
Back Door Guest Suit, charming downtown area, 2 minute walk to Missouri River.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's it like to stay at an apartment in Defiance?
You’ll find 10 apartments to choose from in Defiance for your stay.
Why choose an apartment versus a traditional hotel?
Often more spacious than a traditional hotel room, an apartment includes a kitchen for convenient home-cooked meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want something in a quieter part of town.
What's a favorite apartment for a stay in Defiance?
Here are some of the top apartments in the area: Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues: Located in Ballwin, 14.1 mi/22.7 km from the heart of Defiance. Includes fireplaces and Smart TVs. Access to onsite laundry facilities is available on site. The Lofts of North Main Street: Located 19.2 mi/30.8 km away in St. Charles. Free WiFi, sofa beds, and Smart TVs are included. Access to onsite laundry facilities is available on site. Overlook Main St. in this 2 Bedroom Owners Suite!: Located in St. Charles, 18.5 mi/29.7 km away. Includes private patios, sofa beds, and Smart TVs. Access to onsite laundry facilities is available on site. Prime Loft of Main Street: Located 19.2 mi/30.9 km away in St. Charles. Free WiFi, sofa beds, and Smart TVs are included. Access to onsite laundry facilities is available on site. Private Basement Retreat w/ HOT TUB by StayLage: It’s situated in St. Charles, 19.2 mi/30.9 km from Defiance.
How many apartments will I be able to find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather during my trip to Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you’re planning an extended stay in Defiance. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Chandler Hill Vineyards and Sugar Creek Winery are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can save you time when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. You can also search for flights into St. Louis Lambert Intl. Airport (STL), which is 23.5 mi (37.8 km) away. If you’d like to explore around the area, you may want a rental car for your journey.