A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

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Check prices for these dates

In two weeks
23 Oct - 25 Oct
In two months
4 Dec - 6 Dec
In three months
1 Jan - 3 Jan
In four months
29 Jan - 31 Jan

Our top choices for Defiance apartments

A hotel pool area with a rectangular pool, lounge chairs, and a wooden bench.

1. Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
4.0 out of 10, (1 review)
"Property was dirty, kitchen hadn’t been cleaned. Microwave had food spilled all over inside. Place felt grimy."
United States
Jenny D.
The price is AED 546
AED 725 total
includes taxes & fees
11 Oct - 12 Oct
Great for Business Travelers! Pool + Gym
A room with a dark wooden wall, a brown leather sofa, a white door, and a patterned wall.

2. Stylish1BRStudioCleanQuietandCozy

Stylish1BRStudioCleanQuietandCozy
Saint Charles
10.0 out of 10, Exceptional, (3 reviews)
"Room was very clean with little to no issues at all. Host was super easy to work with and get information from. This spot is within 15-20minutes OR LESS to anything you’d need to do in the ofallon and surrounding areas. I’d book it again if I needed to."
United States
Mike S.
The price is AED 459
AED 1,155 total
includes taxes & fees
6 Nov - 7 Nov
Stylish1BRStudioCleanQuietandCozy
A two-story building with a balcony, a staircase, and a gated entrance.

3. 2nd Street -Deck Suite (back entrance)

2nd Street -Deck Suite (back entrance)
Washington
10.0 out of 10, Exceptional, (10 reviews)
"Great comfortable mini apartment style."
United States
Ozzy
The price is AED 343
AED 694 total
includes taxes & fees
3 Nov - 4 Nov
2nd Street -Deck Suite (back entrance)
A set of stone steps leading to a garage with a car parked inside.

4. Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues

Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues
Ballwin
7.8 out of 10, Good, (24 reviews)
"Rooms were clean and everything we needed for our stay."
United States
Keith K.
The price is AED 248
AED 541 total
includes taxes & fees
19 Oct - 20 Oct
Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues
A bedroom with a bed, a dresser, a mirror, a ceiling fan, and a door leading to another room.

5. Enjoyable 2-bedroom apartment at St. Peters; Near STL

Enjoyable 2-bedroom apartment at St. Peters; Near STL
St. Peters
The price is AED 397
AED 994 total
includes taxes & fees
19 Oct - 20 Oct
Enjoyable 2-bedroom apartment at St. Peters; Near STL
A front door with a sign for '2nd St Loft' and a 'Self Check In' option.

6. 2nd Street Loft - Riverview

2nd Street Loft - Riverview
Washington
10.0 out of 10, Exceptional, (19 reviews)
"Everything was great room was very clean"
United States
Chance W.
The price is AED 315
AED 641 total
includes taxes & fees
13 Oct - 14 Oct
2nd Street Loft - Riverview
Living area

7. Family Friendly w/ Game Room in Quiet Neighborhood

Family Friendly w/ Game Room in Quiet Neighborhood
Wentzville
10.0 out of 10, Exceptional, (2 reviews)
"Nice house for our week in Lake St. Louis area. Accurate description of what you are getting and clean house. Would stay again if we are back in the area"
United States
Campbell W.
The price is AED 826
AED 1,759 total
includes taxes & fees
12 Oct - 13 Oct
Family Friendly w/ Game Room in Quiet Neighborhood
A laundry room with a washer and dryer, a white laundry basket, and a door with a keyhole.

8. Otto's Third | River View Loft by Borgia Church

Otto's Third | River View Loft by Borgia Church
Washington
The price is AED 1,114
AED 1,363 total
includes taxes & fees
13 Oct - 14 Oct
Otto's Third | River View Loft by Borgia Church
A living room with a white sofa, two armchairs, a wooden coffee table, and a side table with a plant.

9. The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail

The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail
Marthasville
8.4 out of 10, Very good, (5 reviews)
"This was the perfect place for my friends and I to stay in Marthasville. Lots of space and amenities. We did not use the complimentary breakfast, but is a great addition. Would recommend to anyone staying in the area. "
United States
Adam K.
The price is AED 918
AED 1,776 total
includes taxes & fees
14 Oct - 15 Oct
The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail
A hotel lobby with a staircase, a reception desk, and a chandelier.

10. 2 Queen Beds | Non-Smoking, Kitchen

2 Queen Beds | Non-Smoking, Kitchen
Westport
8.6 out of 10, Excellent, (47 reviews)
"Fantastic place!"
United States
Anonymous traveler
The price is AED 204
AED 237 total
includes taxes & fees
18 Oct - 19 Oct
2 Queen Beds | Non-Smoking, Kitchen
Free breakfast available on-site.

11. Studio | Lovely Suite Close to Edward Jones!

Studio | Lovely Suite Close to Edward Jones!
Westport
The price is AED 703
AED 919 total
includes taxes & fees
11 Oct - 12 Oct
Studio | Lovely Suite Close to Edward Jones!
A neatly made bed with a stack of folded towels, a bedside lamp, and a ceiling fan in a room with a large window and a wall-mounted artwork.

12. Walk to Main | Pet-Friendly Yard & Workspace

Walk to Main | Pet-Friendly Yard & Workspace
St. Charles Historic District
10.0 out of 10, Exceptional, (12 reviews)
"Very close to downtown St. Charles and the Kati Trail. The home is cute and bed is comfortable. Easy check in process and fenced in back yard was nice to have."
United States
Jessica S.
The price is AED 494
AED 1,052 total
includes taxes & fees
18 Oct - 19 Oct
Walk to Main | Pet-Friendly Yard & Workspace
A modern kitchen with stainless steel appliances, white cabinetry, and a brick accent wall.

13. Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (39 reviews)
"Lovely place to stay!"
United States
Margaret A.
The price is AED 397
AED 1,205 total
includes taxes & fees
12 Oct - 13 Oct
Historic Main St. Customs House Upstairs Apartment
A cozy living room with a brick wall, a white sofa with colorful cushions, a small black table, and a potted plant.

14. Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (120 reviews)
"Host was great. The cutest place in the perfect spot! "
United States
Anonymous traveler
The price is AED 511
AED 1,018 total
includes taxes & fees
11 Oct - 12 Oct
Prime Loft of Main Street
A modern kitchen with white cabinets, a black refrigerator, a stainless steel microwave, and a black oven. There are four blue bowls on a wooden table with a woven placemat.

15. Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi

Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi
Moscow Mills
10.0 out of 10, Exceptional, (14 reviews)
"Great place, nice neighborhood. "
United States
Julie L.
The price is AED 461
AED 990 total
includes taxes & fees
12 Oct - 13 Oct
Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi
A parking lot with marked spaces, a building with a blue facade, and a staircase leading to a second floor.

16. The Oak & Aura Retreat

The Oak & Aura Retreat
St. Charles Historic District
8.0 out of 10, Very good, (2 reviews)
"Great location, and very clean! Would stay here again!"
United States
Rachel B.
The price is AED 423
AED 1,122 total
includes taxes & fees
12 Oct - 13 Oct
The Oak & Aura Retreat
A hallway with a door, two potted plants, a doormat, and a view of a brick building through large windows.

17. Dog-Friendly 2BR | Walk to Main Street

Dog-Friendly 2BR | Walk to Main Street
Saint Charles
8.0 out of 10, Very good, (5 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
The price is AED 428
AED 1,077 total
includes taxes & fees
21 Oct - 22 Oct
Dog-Friendly 2BR | Walk to Main Street
A modern kitchen with white cabinets, a built-in microwave, a stove, and a window providing natural light.

18. Pet-Friendly Duplex | Historic Main

Pet-Friendly Duplex | Historic Main
St. Charles Historic District
10.0 out of 10, Exceptional, (26 reviews)
"Great location"
United States
todd p.
The price is AED 520
AED 1,057 total
includes taxes & fees
18 Oct - 19 Oct
Pet-Friendly Duplex | Historic Main
A row of multi-story buildings with commercial storefronts, including a cafe and a restaurant.

19. Historic Main Street Studio | Dog-Friendly

Historic Main Street Studio | Dog-Friendly
St. Charles Historic District
9.2 out of 10, Wonderful, (40 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
Historic Main Street Studio | Dog-Friendly
A cozy living room with a sofa, chairs, a coffee table, and a clock.

20. 1st Capitol Mansion - Suite 401

1st Capitol Mansion - Suite 401
St. Charles Historic District
7.4 out of 10, Good, (9 reviews)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
1st Capitol Mansion - Suite 401
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

The Wildwood Hotel

The Wildwood Hotel

10/10 Excellent
"The only thing is the beds aren’t the most comfy, too hard for me and light comes in through the side and bottom of the door from the hallway"
lisa 1-night trip
Posted 1 hour ago
The Wildwood Hotel

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your stay.
Why choose an apartment versus a traditional hotel?
Often more spacious than a traditional hotel room, an apartment includes a kitchen for convenient home-cooked meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want something in a quieter part of town.
What's a favorite apartment for a stay in Defiance?
Here are some of the top apartments in the area: 2 Queen Beds | Non-Smoking, Kitchen: Situated in Maryland Heights, 18.7 mi/30.1 km from the heart of Defiance. Includes free WiFi and Smart TVs. 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed: Located 18.7 mi/30.1 km away in Maryland Heights. Free WiFi and Smart TVs are included. The Lofts of North Main Street: Located in St. Charles, 19.2 mi/30.8 km away. Includes free WiFi, sofa beds, and Smart TVs. Access to onsite laundry facilities is available on site. Driftwood Den | Boho 2BR | Dog-Friendly: It's located in St. Charles, 19 mi/30.6 km from Defiance. Includes free WiFi.
How many apartments will I be able to find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather during my trip to Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you're planning an extended stay in Defiance. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Yellow Farmhouse Winery and Chandler Hill Vineyards are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can save you time when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. You can also search for flights into St. Louis Lambert Intl. Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, you may want a rental car for your journey.