Resorts & Hotels with Spas in Santa Cruz from AED 340
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Santa Cruz Resorts & Hotels with Spas
Pick from 27 Santa Cruz Resorts & Hotels with Spas with updated room rates, reviews, and availability. Most hotels are fully refundable.

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
9.0 out of 10, Wonderful, (318)
The price is AED 481
AED 481 total
11 Jul - 12 Jul

Swissôtel Santa Cruz De La Sierra
Swissôtel Santa Cruz De La Sierra
9.2 out of 10, Wonderful, (76)
The price is AED 734
AED 734 total
29 Jun - 30 Jun

Hotel Cortez
Hotel Cortez
9.0 out of 10, Wonderful, (108)
The price is AED 410
AED 410 total
21 Jun - 22 Jun

Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra Hotel
9.0 out of 10, Wonderful, (191)
The price is AED 584
AED 584 total
22 Jun - 23 Jun

Camino Real Hotel
Camino Real Hotel
8.8 out of 10, Excellent, (386)
The price is AED 494
AED 494 total
27 Jun - 28 Jun

Sun Hotel
Sun Hotel
8.2 out of 10, Very Good, (297)

Cosmopolitano Hotel Boutique
Cosmopolitano Hotel Boutique
9.2 out of 10, Wonderful, (121)

Apart Hotel Toborochi
Apart Hotel Toborochi
8.8 out of 10, Excellent, (60)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Recent reviews of Santa Cruz hotels
Recent reviews of Santa Cruz hotels

Camino Real Hotel
5/5 Excellent
"Great Hotel, had a great time ."
A verified traveler stayed at Camino Real Hotel
Posted 2 weeks ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
More Hotel Options in Santa Cruz
- Hotels with WiFi in Santa Cruz
- Hotels with Free Parking in Santa Cruz
- Hotels with a Pool in Santa Cruz
- Business Hotels in Santa Cruz
- Family Hotels in Santa Cruz
- Hotel with a Concierge in Santa Cruz
- Hotels with Bars in Santa Cruz
- Shopping Hotels in Santa Cruz
- Hotels with smoking rooms in Santa Cruz
- Hotels with Hot Tubs in Santa Cruz
- Pet-friendly Hotels in Santa Cruz
- Adventure Hotels in Santa Cruz
- Hotel Wedding Venues in Santa Cruz
- Cheap Hotels in Santa Cruz
- Historic Hotels in Santa Cruz
- Golf Hotels in Santa Cruz
- Hotels with Waterslides in Santa Cruz
- Hotels with an Indoor Pool in Santa Cruz
- Romantic Hotels in Santa Cruz
- Beach Hotels in Santa Cruz
More Themes
- All-inclusive Hotel
- Hotels with Bars
- Beach Hotels
- Boutique Hotels
- Cheap Hotels
- Business Hotels
- Casinos
- Hotel with a Concierge
- Family Hotels
- Hotels with Free Parking
- Golf Hotels
- Historic Hotels
- Hotels with Hot Tubs
- Hotels with an Indoor Pool
- Apartment Hotel
- Hotels with a Lazy River
- Luxury Hotels
- Pet-friendly Hotels
- Hotels with a Pool
- Adventure Hotels
- Romantic Hotels
- Shopping Hotels
- Ski Hotels
- Hotels with smoking rooms
- Green Hotels
- Waterpark Hotels
- Hotels with Waterslides
- Hotel Wedding Venues
- Hotels with WiFi
- Winery Hotels
Stay near popular Santa Cruz attractions
- Hotels near Ventura Mall
- Hotels near Plaza 24 de Septiembre
- Hotels near Santa Cruz Zoo
- Hotels near Guembe Biocenter
- Hotels near San Lorenzo Cathedral
- Hotels near Amboró National Park
- Hotels near La Recova Artisan Walk
- Hotels near Cine Center
- Hotels near Blacutt Square
- Hotels near Lomas de Arena Regional Park
Discover hotels close to Santa Cruz with room rates, reviews, and availability. Most hotels are fully refundable.
- Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
- Camino Real Hotel
- Marriott Santa Cruz de la Sierra Hotel
- Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
- Novotel Santa Cruz De La Sierra
- Lido Hotel
- Delfines Collection Hotel By Mercure
- TRYP by Wyndham Santa Cruz
- Hotel Las Américas
- Sun Hotel