The Best Business Hotels in Florida Keys from AED 539 in 2026 | Expedia

A beach with palm trees, people relaxing on chairs, and colorful kayaks.

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Check availability on Florida Keys Business Hotels

Tonight

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10 Oct - 11 Oct

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Next weekend

16 Oct - 18 Oct

Our top choices for Florida Keys business-friendly hotels

A pool area with lounge chairs and umbrellas, surrounded by palm trees.

A hotel room with a large bed, a wooden nightstand, a desk, a chair, and a window with curtains.

An outdoor patio area with tables and chairs, a bar area with a counter and bar stools, and a TV mounted on the wall.

A wooden outdoor dining table set with glassware, candles, and lanterns, surrounded by lush greenery.

1. Fairfield by Marriott Inn & Suites Key West at The Keys Collection

New Town

United States

Brian

AED 459

AED 620 total

includes taxes & fees

15 Oct - 16 Oct

A pool area with lounge chairs and umbrellas, surrounded by palm trees and a view of the ocean.

A hotel room with a balcony, a bed, a desk, and two chairs.

A modern kitchen with a marble island, wooden cabinets, and pendant lighting.

A bar area with a thatched roof, wooden chairs, and a poolside view.

2. Hampton Inn Key West FL

Key West

United States

Jaycie

AED 666

AED 749 total

includes taxes & fees

13 Oct - 14 Oct

A swimming pool with water splashing, surrounded by palm trees and a building in the background.

A two-story yellow house with a porch, white railings, and green shutters.

The exterior of the Silver Palms Inn with a two-story structure, a green awning over the entrance, and a palm tree to the right.

The entrance to Silver Palms Inn with a reception desk, a seating area, and a glass door.

3. Silver Palms Inn & Historic Homes

Old Town Key West

United States

sam

AED 393

AED 691 total

includes taxes & fees

25 Oct - 26 Oct

Pool

A spacious living area with a sofa, chairs, a coffee table, and a foosball table. Large windows offer a view of the outdoor area.

A hotel room with a bed, a sofa, a round table with a book, a window with a view, and a radiator.

A couple holding hands in a tropical setting with palm trees and greenery.

4. Blue Flamingo Resort Key West

New Town

United States

Esteban

AED 459

AED 724 total

includes taxes & fees

11 Oct - 12 Oct

A swimming pool surrounded by palm trees and a natural rock formation.

A cozy room with wicker furniture, a glass coffee table, and a view of lush greenery outside.

A covered outdoor seating area with a pool in the background.

A spacious lobby with a central seating area, two staircases, and multiple potted plants.

5. Havana Cabana at Key West

New Town

United States

Stephanie

AED 518

AED 816 total

includes taxes & fees

25 Oct - 26 Oct

Pool

Pool

A sign for Doubletree by Hilton Grand Key Resort surrounded by lush greenery and palm trees.

View from room

6. DoubleTree Resort by Hilton Grand Key - Key West

Key West

United States

Nancy

AED 467

AED 650 total

includes taxes & fees

27 Oct - 28 Oct

A hotel room with a bed, a view of the beach, a hammock, and beach chairs.

A pool area with blue lounge chairs, a hot tub, and a covered seating area.

A beachfront restaurant with outdoor seating, a seafood sign, and a market sign.

A beachfront hotel with multiple colorful buildings, a pool area, and a boat dock.

7. Ibis Bay Beach Resort

Northside Resort

United States

Andre

AED 420

AED 592 total

includes taxes & fees

11 Oct - 12 Oct

A beach with palm trees and lounge chairs.

A hotel room with a large bed, a ceiling fan, a nightstand with a lamp, and a view of the beach through the window.

A swimming pool with clear blue water, surrounded by a white deck and a black metal fence.

A balcony with two blue lounge chairs, a wooden ceiling, and a view of the ocean and palm trees.

8. Chesapeake Beach Resort

Matecumbe

United States

Leihla

AED 555

AED 831 total

includes taxes & fees

13 Oct - 14 Oct

View all properties

Top Florida Keys Hotel Reviews

The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent

"Todo muy limpio. La playita y las condiciones al rededor de esta son excelentes. Muy buena atención de la recepcionista en la oficina. Lo recomiendo mucho"

Hawks Cay Resort

Hawks Cay Resort

10/10 Excellent

"Great hotel. Definitely coming back!"

Sunset Cove Beach Resort

Sunset Cove Beach Resort

10/10 Excellent

"Pet friendly"

Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent

"Está es mi segunda vez , visitando el resort, la atención es muy buena , la limpieza un 10 de 10 , la piscina tiene buen horario, Carlos en el mejor bartender , el único inconveniente es que cierran el bar muy temprano, porque ? Sería bueno que estuviera abierto hasta más tarde"

Kingsail Resort

Kingsail Resort

10/10 Excellent

"Quite and Relaxing place."

Amara Cay Resort

Amara Cay Resort

10/10 Excellent

"Very clean resort. The pool was fabulous. The tiki bar was great. Stall friendly and helpful. Truly enjoyed my stay!"