A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Find Business Hotels in Florida Keys

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Florida Keys Business Hotels

Our top choices for Florida Keys business-friendly hotels

Outdoor pool, open 6:00 AM to 11:00 PM, free cabanas, sun loungers

Hampton Inn & Suites Miami/Brickell-Downtown

Hampton Inn & Suites Miami/Brickell-Downtown
3.5 star property
Brickell
9.4 out of 10, Exceptional, (4,173 reviews)
"Was very close to the Cruise terminal and great location! I would definitely stay there again!"
United States
Ty
The price is AED 494
AED 558 total
includes taxes & fees
27 Jul - 28 Jul
Hampton Inn & Suites Miami/Brickell-Downtown
Free daily buffet breakfast

Embassy Suites by Hilton Miami International Airport

Embassy Suites by Hilton Miami International Airport
4.0 star property
Palmer Lake
8.6 out of 10, Excellent, (4,831 reviews)
"This was the perfect location for our family vacation that included a cruise! Everyone was welcoming and kind. Definitely the way to go when traveling with large families!"
United States
Amber
The price is AED 393
AED 444 total
includes taxes & fees
3 Aug - 4 Aug
Embassy Suites by Hilton Miami International Airport
Reception

Hampton Inn & Suites Miami Wynwood Design District

Hampton Inn & Suites Miami Wynwood Design District
3.0 star property
Midtown
9.0 out of 10, Wonderful, (3,439 reviews)
"Great location and good breakfast."
United States
Patricia
The price is AED 311
AED 351 total
includes taxes & fees
3 Aug - 4 Aug
Hampton Inn & Suites Miami Wynwood Design District
Bar (on property)

Fairfield Inn & Suites by Marriott Marathon Florida Keys

Fairfield Inn & Suites by Marriott Marathon Florida Keys
3.0 star property
Marathon
9.2 out of 10, Wonderful, (1,180 reviews)
"We had a great stay! Enjoyed the breakfast! and the pool!"
United States
Cathy
The price is AED 526
AED 591 total
includes taxes & fees
9 Aug - 10 Aug
Fairfield Inn & Suites by Marriott Marathon Florida Keys
On the beach, sun loungers, beach umbrellas, beach towels

Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa
5.0 star property
Marathon
9.2 out of 10, Wonderful, (1,195 reviews)
"Beautiful resort will.be going back"
United States
Robert
The price is AED 884
AED 1,219 total
includes taxes & fees
9 Aug - 10 Aug
Isla Bella Beach Resort & Spa
Room, 1 King Bed, Bay View | Beach/ocean view

Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay
2.5 star property
Key Largo
8.8 out of 10, Excellent, (1,023 reviews)
"Nice location, great staff"
United States
sergio
The price is AED 450
AED 506 total
includes taxes & fees
9 Aug - 10 Aug
Hampton Inn Key Largo Manatee Bay
Hibiscus Waterfront 2-Bedroom, Two Bath Master Suite (Brand New) | Terrace/patio

Lime Tree Bay Resort

Lime Tree Bay Resort
3.5 star property
Long Key
9.2 out of 10, Wonderful, (1,380 reviews)
"Isolated escape from the usual packed & crowded resorts. Loves how the beach was just steps away from our door step. A definite A+ resort without all the unecessary glam"
United States
Shannon
The price is AED 479
AED 704 total
includes taxes & fees
13 Jul - 14 Jul
Lime Tree Bay Resort
On the beach, beach cabanas, sun loungers

Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys

Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys
3.0 star property
Marathon
9.0 out of 10, Wonderful, (1,014 reviews)
"Great, location"
United States
Lima
The price is AED 555
AED 769 total
includes taxes & fees
10 Aug - 11 Aug
Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys
Outdoor pool, pool umbrellas, sun loungers

Hampton Inn Key West FL

Hampton Inn Key West FL
2.5 star property
Key West
9.0 out of 10, Wonderful, (1,426 reviews)
"Very clean, convenient and close to town but away from the hustle and bustle of the night life. Perfect for a family vacation. Great breakfast, pool was beautiful and rooms were big and comfy!"
United States
Chloe
The price is AED 590
AED 664 total
includes taxes & fees
11 Aug - 12 Aug
Hampton Inn Key West FL
Balcony

Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,346 reviews)
"The room and property are clean and the staff is friendly and helpful."
United States
Brenna
The price is AED 614
AED 959 total
includes taxes & fees
16 Jul - 17 Jul
Cheeca Lodge & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Florida Keys Hotel Reviews

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"Everything"
Gloria 2-night trip
Posted less than an hour ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Explore a world of travel with Expedia