The Best Business Hotels in Florida Keys from AED 344 in 2026

Check availability on Florida Keys Business Hotels

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Florida Keys business-friendly hotels

A pool area with lounge chairs and umbrellas, surrounded by palm trees.

1. Fairfield by Marriott Inn & Suites Key West at The Keys Collection

New Town

Jacob

AED 678 total

includes taxes & fees

29 Oct - 30 Oct

A pool area with lounge chairs and umbrellas, surrounded by palm trees and a view of the ocean.

2. Hampton Inn Key West FL

Key West

Heylin

AED 740 total

includes taxes & fees

29 Oct - 30 Oct

A wooden boardwalk with a palm tree and lamp post, leading to a waterfront.

3. Courtyard by Marriott Key West Waterfront

Northside Resort

Patrick

AED 740 total

includes taxes & fees

29 Oct - 30 Oct

4. Blue Flamingo Resort Key West

New Town

Gabriel

AED 686 total

includes taxes & fees

29 Oct - 30 Oct

A swimming pool with lounge chairs and palm trees.

5. Hilton Garden Inn Key West / The Keys Collection

New Town

Darlene

AED 576 total

includes taxes & fees

17 Nov - 18 Nov

An aerial view of a resort with two swimming pools surrounded by palm trees and sun loungers.

6. Islander Resort

Matecumbe

DEBORAH

AED 1,042 total

includes taxes & fees

15 Nov - 16 Nov

A beach with palm trees, lounge chairs, and a clear view of the ocean.

7. Hampton Inn Key Largo Manatee Bay

Key Largo

Joliene

AED 541 total

includes taxes & fees

17 Nov - 18 Nov

A swimming pool surrounded by palm trees and a natural rock formation.

8. Havana Cabana at Key West

New Town

Stephanie

AED 862 total

includes taxes & fees

16 Nov - 17 Nov

View all properties

Top Florida Keys Hotel Reviews

Baker's Cay Resort Key Largo, Curio Collection by Hilton

8/10 Good

"Good stay"

Islander Resort

10/10 Excellent

"I booked Islander Resor, and I’m genuinely happy I did. From the moment I arrived, I felt I had made the right choice. The resort has a beautiful, peaceful atmosphere that immediately makes you feel relaxed and comfortable. What impressed me most was the attention to detail. I naturally notice these things wherever I go, and I truly appreciated the thought behind every element. From the restaurant’s dishware and lighting to the outdoor furniture, landscaping, and decorative touches, everything feels carefully selected and beautifully put together. It’s clear that someone put real care into creating this experience. One of the things I loved most was the location. You can wake up to a gorgeous sunrise right at the resort, spend the day enjoying the property without needing to go anywhere, and then drive just a few minutes to the bayside for an incredible sunset with a cocktail in hand. To me, great hospitality is about how a place makes you feel, not just what it offers. Islander Resort made me feel comfortable, relaxed, and genuinely happy to be there. I left with wonderful memories and a real appreciation for the people behind this beautiful property. I would absolutely return and highly recommend it!"

Kingsail Resort

10/10 Excellent

"We were pleasantly surprised by the spacious, well-equipped room, which had a stove, fridge, and microwave. The room was clean and the king sized bed was really comfortable. The front desk staff were very kind and helpful. This resort offers a great value for the money and we will be staying here again."

The Pelican Key Largo Cottages

8/10 Good

"My room looked different than the one on the website did not include a table and chairs and the small fridge was next to bathroom, room was pretty outdated and close to highway which made it hard to sleep even with mask and ear plugs, the a/c works well but very noisy. Now the office staff were super helpful and excellent customer service very friendly, the grounds are beautiful plenty of chairs and places to sit to eat or relax, very pretty, I loved that my room had couple of chairs outside front door of room that was a nice addition,"

Room 1

Change your mind

Treat yourself

Be picky

Check availability on Florida Keys Business Hotels

Our top choices for Florida Keys business-friendly hotels

1. Fairfield by Marriott Inn & Suites Key West at The Keys Collection

2. Hampton Inn Key West FL

3. Courtyard by Marriott Key West Waterfront

4. Blue Flamingo Resort Key West

5. Hilton Garden Inn Key West / The Keys Collection

6. Islander Resort

7. Hampton Inn Key Largo Manatee Bay

8. Havana Cabana at Key West

9. DoubleTree Resort by Hilton Grand Key - Key West

10. The Reach Key West, Curio Collection by Hilton

Top Florida Keys Hotel Reviews

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Waterside Suites & Marina

Amara Cay Resort

Islander Resort

Kingsail Resort

The Pelican Key Largo Cottages

Bayside Inn Key Largo

Hampton Inn Key Largo Manatee Bay

Find Business Hotels in Florida Keys

Change your mind

Treat yourself

Be picky

Check availability on Florida Keys Business Hotels

Our top choices for Florida Keys business-friendly hotels

1. Fairfield by Marriott Inn & Suites Key West at The Keys Collection

2. Hampton Inn Key West FL

3. Courtyard by Marriott Key West Waterfront

4. Blue Flamingo Resort Key West

5. Hilton Garden Inn Key West / The Keys Collection

6. Islander Resort

7. Hampton Inn Key Largo Manatee Bay

8. Havana Cabana at Key West

9. DoubleTree Resort by Hilton Grand Key - Key West

10. The Reach Key West, Curio Collection by Hilton

Top Florida Keys Hotel Reviews

Baker's Cay Resort Key Largo, Curio Collection by Hilton