Uptown Greenville, NC

Greenville

Uptown Greenville
Uptown Greenville

Popular places to visit

Town Common

Learn about the local history of Greenville with a stop at Town Common.

Town Common

Greenville Museum of Art

You can spend time studying the exhibits at Greenville Museum of Art in Greenville.

Greenville Museum of Art

East Carolina University

Enjoy the collegiate vibe when you visit East Carolina University, during your trip to Greenville. Check out the shops and top-notch restaurants in this family-friendly area.

East Carolina University

ECU Health Medical Center

Though ECU Health Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Greenville while you are here.

ECU Health Medical Center

Greenville VA Medical Center

Though Greenville VA Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Greenville while you are here.

Greenville VA Medical Center

Dowdy–Ficklen Stadium

Catch an event at Dowdy–Ficklen Stadium during your trip to Greenville. Check out the shops and top-notch restaurants in this family-friendly area.

Dowdy–Ficklen Stadium

Uptown Greenville Hotel Deals

Hilton Garden INN Greenville University

Hilton Garden INN Greenville University

3 out of 5
423 EVANS ST, Greenville, NC
The price is AED 496 per night from Oct 5 to Oct 6
AED 496
AED 561 total
5 Oct - 6 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Popular attractions Greenville ...
9.2/10 Wonderful! (68 reviews)
"Beautiful clean and great location"

Reviewed on 14 September 2025

Hilton Garden INN Greenville University
Staybridge Suites Greenville Medical Center by IHG

Staybridge Suites Greenville Medical Center by IHG

3 out of 5
930 Crosswind Street, Greenville, NC
Fully refundable
The price is AED 342 per night from Oct 15 to Oct 16
AED 342
AED 386 total
15 Oct - 16 Oct
includes taxes & fees
Stay at this 3-star hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Guy Smith Stadium and North Pines are located ...
9.2/10 Wonderful! (124 reviews)
"Nice, new hotel. Good breakfast and weekday happy hour was a nice bonus. 2-bedroom suite was perfect for traveling with kids. Have stayed there twice. Like it a lot."

Reviewed on 19 September 2025

Staybridge Suites Greenville Medical Center by IHG
Microtel Inn & Suites by Wyndham Greenville/University Medic

Microtel Inn & Suites by Wyndham Greenville/University Medic

2 out of 5
450 Moye Blvd, Greenville, NC
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7/10 Good! (1,007 reviews)
"Great front desk staff at check in and departure. Beds comfortable. Housekeeping knocked at 7am and woke us up! Breakfast bar largely unattended and littered."

Reviewed on 12 September 2025

Get rates
Microtel Inn & Suites by Wyndham Greenville/University Medic
Baymont by Wyndham Greenville

Baymont by Wyndham Greenville

2.5 out of 5
3439 S Memorial Drive, Greenville, NC
The price is AED 240 per night from Sep 30 to Oct 1
AED 240
AED 272 total
30 Sep - 1 Oct
includes taxes & fees
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.4/10 (1,002 reviews)
"The property was alright and the amenities were fine. Close to where I needed to go."

Reviewed on 27 August 2025

Baymont by Wyndham Greenville
Comfort Inn & Suites Greenville Near Convention Center

Comfort Inn & Suites Greenville Near Convention Center

2.5 out of 5
3212 S Memorial Dr, Greenville, NC
The price is AED 393 per night from Sep 28 to Sep 29
AED 393
AED 445 total
28 Sep - 29 Sep
includes taxes & fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (354 reviews)
"Would stay here again."

Reviewed on 11 September 2025

Comfort Inn & Suites Greenville Near Convention Center
Best Western Plus Suites-Greenville

Best Western Plus Suites-Greenville

2.5 out of 5
2310 Greenville Boulevard NE, Greenville, NC
The price is AED 415 per night from Sep 29 to Sep 30
AED 415
AED 469 total
29 Sep - 30 Sep
includes taxes & fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,004 reviews)
"5 star review for all clean room, staff, and parking."

Reviewed on 19 September 2025

Best Western Plus Suites-Greenville
See all 186 properties in Uptown Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Uptown Greenville

Default Image

Greenville Heights

When in Greenville Heights, you can plan a visit to Town Common and Williams Arena at Minges Coliseum, some noteworthy sights in the nearby area.

Greenville Heights
Default Image

College View Historic District

When in College View Historic District, you can plan a visit to Williams Arena at Minges Coliseum and Dowdy–Ficklen Stadium, some noteworthy sights in the nearby area.

College View Historic District
Default Image

Medical District

While there might not be top attractions in Medical District, you can explore the larger area and discover places like Arlington Crossing and Town Common.

Medical District
Default Image

Westhaven

While Westhaven isn't home to many top sights, 11 Galleria and Bowlero East Carolina are some notable places to visit nearby.

Westhaven

Uptown Greenville, NC

Choose two or more items and save on your trip: