A brick-paved street lined with historic buildings and a yellow fire hydrant.

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Check prices for these dates

Tonight
12 Oct - 13 Oct
Tomorrow
13 Oct - 14 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

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Our top choices for Historic Main Street hotels

A brick building with a sign reading "Country Inn & Suites."
An indoor swimming pool with a tiled floor, a central window, and multiple chairs around the pool.
A modern kitchen with blue cabinetry, a central island with stools, pendant lighting, and a variety of kitchen appliances and utensils.
A spacious living room with a large window, a wooden bookshelf, a green sofa, and a coffee table.

1. Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
St. Charles Historic District, 1 km from Historic Main Street
United States
Roseanna
AED 466
AED 536 total
includes taxes & fees
1 Nov - 2 Nov
Country Inn & Suites by Radisson, St. Charles Historic District
A large hotel with a prominent tower and multiple parking areas.
A spacious lobby with a patterned carpet, a reception desk, and a seating area with a sofa and chairs.
A bar area with a long counter, multiple screens, and seating.
A lobby with a large screen displaying "Hollywood Casino" and "Wood Casino" signs, multiple chandeliers, and a polished floor.

2. Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3 km from Historic Main Street
United States
Nicole
AED 347
AED 461 total
includes taxes & fees
1 Nov - 2 Nov
Hollywood Casino & Hotel St. Louis
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.
A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.
A bakery display case with various pastries and cakes.

3. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
1.4 km from Historic Main Street
United States
Kara
AED 658
AED 830 total
includes taxes & fees
13 Oct - 14 Oct
Ameristar Casino Resort and Spa
A modern hotel with a prominent Hilton logo, multiple floors, and a well-lit entrance.
A modern lounge area with seating arrangements, tables, and hanging pendant lights.
A modern lounge area with sofas, tables, and chairs, featuring a mix of seating arrangements and a central coffee station.
A self-service beverage station with a refrigerated display and a microwave.

4. Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO
2.1 km from Historic Main Street
United States
Kippi
AED 465
AED 539 total
includes taxes & fees
1 Nov - 2 Nov
Tru by Hilton St. Charles St. Louis, MO
A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.
A hotel lobby with a wooden floor, a reception desk, two armchairs, a sofa, and large windows with a view of buildings outside.
A spacious lobby with a reception desk, a seating area with a sofa, a vending machine, and a wall-mounted clock.
A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

5. Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
1.5 km from Historic Main Street
United States
Bryan
AED 346
AED 398 total
includes taxes & fees
18 Oct - 19 Oct
Comfort Suites St Charles - St Louis
Exterior
A spacious lobby with a modern design, featuring a large seating area with sofas and chairs, a patterned carpet, and a view of the outside through large windows.
A modern kitchen with white cabinets, a long countertop, and overhead lighting.
Property amenity

6. Elimwood Hotel, a Ramada by Wyndham

Elimwood Hotel, a Ramada by Wyndham
3.1 km from Historic Main Street
United States
Harry
AED 259
AED 303 total
includes taxes & fees
2 Nov - 3 Nov
Elimwood Hotel, a Ramada by Wyndham
A restaurant with a long wooden table, cushioned seating, and decorative lanterns.
A lobby with a checkered floor, a sofa, armchairs, a small table, and a water dispenser.
A compact kitchen with dark wooden cabinets, a built-in microwave, and a stainless steel refrigerator.
A hotel room with two beds, a nightstand with a lamp, a framed picture on the wall, and a patterned carpet.

7. Holiday Inn St. Louis Arpt West-Earth City by IHG

Holiday Inn St. Louis Arpt West-Earth City by IHG
2.9 km from Historic Main Street
United States
Bryan
AED 371
AED 430 total
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn St. Louis Arpt West-Earth City by IHG
A spacious lobby with a reception desk, seating area, and a fireplace.
A lobby with a fireplace, several potted plants, a television, and a sofa.
A living room with a beige sofa, a wooden coffee table, a patterned rug, a potted plant, and two framed pictures on the wall.
A hotel room with a large bed, two bedside lamps, a nightstand with a phone and alarm clock, and two framed floral pictures on the wall.

8. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
1.6 km from Historic Main Street
United States
Lynda
AED 281
AED 326 total
includes taxes & fees
13 Oct - 14 Oct
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
A spacious lobby with a central round table, two sofas, and a chandelier.
A buffet setup with various food items and a decorative vase of flowers.
A hotel room with two beds, a patterned wall, and a view of the city through sheer curtains.
A Drury Plaza hotel with a modern design, featuring a curved facade, large windows, and a Drury Plaza sign on the top.

9. Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
15.8 km from Historic Main Street
United States
Chasity
AED 477
AED 554 total
includes taxes & fees
18 Oct - 19 Oct
Drury Plaza Hotel St. Louis Chesterfield
A spacious lobby with a high ceiling, a dining area, and a seating area with sofas and a coffee table.
An outdoor patio area with a table and chairs, a glass door entrance, and a visible interior with a dining area.
A spacious lobby with a blue sofa, round coffee table, and blue chairs. There is a reception desk and a seating area with a high ceiling and large windows.
An indoor swimming pool with clear blue water, a tiled floor, and a ceiling with square vents.

10. Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
12 km from Historic Main Street
United States
Ashley
AED 404
AED 464 total
includes taxes & fees
18 Oct - 19 Oct
Drury Inn & Suites St. Louis St. Peters
A modern kitchen with a bar area, wooden cabinets, and pendant lighting.
A modern hotel entrance with a glass canopy, large windows, and a brick facade.
A hotel room with three computer workstations, each with a monitor, keyboard, and a lamp.
A hotel room with two beds, a sofa, a small table, a lamp, and a framed abstract painting on the wall.

11. Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
15.9 km from Historic Main Street
United States
Debbie
AED 443
AED 514 total
includes taxes & fees
18 Oct - 19 Oct
Hyatt Place St. Louis/Chesterfield
A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.
A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.
A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.
A hotel room with a bed, a desk, a television, and a lamp.

12. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
10.6 km from Historic Main Street
United States
Murphy
AED 331
AED 392 total
includes taxes & fees
18 Oct - 19 Oct
Pear Tree Inn St. Louis Airport
A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.
A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.
A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.
A hotel room with a desk, chair, TV, and a framed picture on the wall.

13. Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
10.7 km from Historic Main Street
United States
Mary
AED 356
AED 422 total
includes taxes & fees
19 Oct - 20 Oct
Wingate by Wyndham St. Louis Airport
An outdoor patio with a built-in grill, seating area, and stone walls.
A multi-story hotel with a parking lot in front.
A spacious lounge area with a stone fireplace, comfortable seating, and a large TV screen.
An indoor swimming pool with clear glass walls, sunlit seating area, and lifeguard station.

14. Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield
15.1 km from Historic Main Street
United States
Chelsea
AED 694
AED 812 total
includes taxes & fees
18 Oct - 19 Oct
Residence Inn by Marriott St. Louis Chesterfield
A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.
A modern lobby with blue seating, a reception desk, and large windows.
A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.
A modern dining area with a long table, multiple chairs, and a unique chandelier.

15. Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
12 km from Historic Main Street
United States
Daisy
AED 404
AED 501 total
includes taxes & fees
20 Oct - 21 Oct
Hyatt Select St. Louis Airport
A spacious lobby with a high ceiling, a reception desk, seating areas, and a staircase leading to an upper level.
A modern lobby with a reception desk, seating area, and a dining section.
A coffee station with two coffee machines and a variety of coffee pods and cups.
A Holiday Inn Express hotel with a modern design, featuring a covered entrance and multiple windows.

16. Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
15.7 km from Historic Main Street
United States
Serah
AED 433
AED 521 total
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express & Suites St Peters by IHG
An outdoor seating area with a table and chairs, a fire feature, and a brick wall.
A modern hotel with a flat roof, large windows, and a prominent signage for 'SPRINGHILL SUITES.'
A bar area with a counter, stools, and shelves with bottles and glasses.
A hotel room with a bed, bedside tables, a wardrobe, and a window with curtains.

17. SpringHill Suites by Marriott St. Louis Chesterfield

SpringHill Suites by Marriott St. Louis Chesterfield
15.4 km from Historic Main Street
United States
Jamie
AED 449
AED 521 total
includes taxes & fees
18 Oct - 19 Oct
SpringHill Suites by Marriott St. Louis Chesterfield
An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.
A snack vending machine with various snack options.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A hotel lobby with a reception desk, seating area, and a view of the parking lot.

18. Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport
11.7 km from Historic Main Street
United States
Leia
AED 473
AED 569 total
includes taxes & fees
29 Oct - 30 Oct
Hampton Inn By Hilton St Louis Airport
A modern lounge area with a stone fireplace, a blue sofa, and a small table.
An outdoor patio area with a stone wall, a grill, and outdoor seating.
A Fairfield Inn & Suites Marriott hotel entrance with a modern design, featuring a brick facade, a covered entrance area, and a clear sky in the background.
A modern lobby with a blue sofa, a reception desk, and a snack bar.

19. Fairfield Inn & Suites St Louis Westport

Fairfield Inn & Suites St Louis Westport
9.5 km from Historic Main Street
United States
Alan
AED 482
AED 563 total
includes taxes & fees
18 Oct - 19 Oct
Fairfield Inn & Suites St Louis Westport
A hotel lobby with a hot tub, a pool, and outdoor seating.
A lobby with seating areas, a reception desk, and a view of the lobby in the background.
A modern lounge area with grey armchairs, a sofa, a TV, and a bookshelf.
A modern coffee shop interior with wooden furniture, a coffee bar, and a sign for 'KELSO+BROS Coffee Roasters'.

20. Drury Plaza Hotel St. Louis Creve Coeur

Drury Plaza Hotel St. Louis Creve Coeur
12.6 km from Historic Main Street
United States
Eryn
AED 481
AED 559 total
includes taxes & fees
2 Nov - 3 Nov
Drury Plaza Hotel St. Louis Creve Coeur
View all properties

Compare popular hotels close to Historic Main Street

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A brick building with a sign reading "Country Inn & Suites."
Country Inn & Suites by Radisson, St. Charles Historic District
9.4
Exceptional
1,101 reviews
View
A large hotel with a prominent tower and multiple parking areas.
Hollywood Casino & Hotel St. Louis
8.6
Excellent
2,225 reviews
View
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
Ameristar Casino Resort and Spa
8.6
Excellent
1,075 reviews
View
A modern hotel with a prominent Hilton logo, multiple floors, and a well-lit entrance.
Tru by Hilton St. Charles St. Louis, MO
8.6
Excellent
878 reviews
View
A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.
Comfort Suites St Charles - St Louis
8.4
Very good
1,005 reviews
View

Hotels recommended for families near Historic Main Street

A brick building with a sign reading "Country Inn & Suites."
An indoor swimming pool with a tiled floor, a central window, and multiple chairs around the pool.
A modern kitchen with blue cabinetry, a central island with stools, pendant lighting, and a variety of kitchen appliances and utensils.
A spacious living room with a large window, a wooden bookshelf, a green sofa, and a coffee table.

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
St. Charles Historic District
AED 466
AED 536 total
includes taxes & fees
1 Nov - 2 Nov
Country Inn & Suites by Radisson, St. Charles Historic District
A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.
A hotel room with two beds, a headboard, bedside lamps, a clock, and a window with curtains.
A hotel pool area with a hot tub, lounge chairs, and a 'No Diving Allowed' sign.
A gym with treadmills, stationary bikes, and a weight machine.

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
St. Charles
AED 533
AED 617 total
includes taxes & fees
18 Oct - 19 Oct
Drury Plaza Hotel St. Louis St. Charles
A grand hotel lobby with a central spiral staircase, multiple balconies, and a large indoor plant.
A multi-level hotel lobby with numerous seating areas, a central water feature, and a variety of plants.
A large hotel building with a prominent sign for 'Embassy Suites.'
A hotel room with a large bed, a desk, a chair, and a bathroom visible through an open door.

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
St. Charles
AED 509
AED 585 total
includes taxes & fees
19 Oct - 20 Oct
Embassy Suites by Hilton St. Louis St. Charles
A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.
A hotel lobby with a wooden floor, a reception desk, two armchairs, a sofa, and large windows with a view of buildings outside.
A spacious lobby with a reception desk, a seating area with a sofa, a vending machine, and a wall-mounted clock.
A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
St. Charles
AED 346
AED 398 total
includes taxes & fees
18 Oct - 19 Oct
Comfort Suites St Charles - St Louis
A modern kitchen with a central island, breakfast bar, and various appliances.
A hotel room with a large bed, a desk, a chair, and a window with a view.
An indoor swimming pool with blue walls, a tiled floor, and lounge chairs.
A snack and drink area with a 'Treats' sign, refrigerated drink dispensers, and shelves stocked with snacks and beverages.

Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
St. Charles
AED 434
AED 521 total
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn & Suites St. Charles Old Town Area
A modern hotel with a prominent Hilton logo, multiple floors, and a well-lit entrance.
A modern lounge area with seating arrangements, tables, and hanging pendant lights.
A modern lounge area with sofas, tables, and chairs, featuring a mix of seating arrangements and a central coffee station.
A self-service beverage station with a refrigerated display and a microwave.

Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO
St. Charles
AED 465
AED 539 total
includes taxes & fees
1 Nov - 2 Nov
Tru by Hilton St. Charles St. Louis, MO
A staircase with white railings and a ceiling fan.
A room with a brick wall, two framed pictures, a white door, and two white chairs with wooden frames.
A modern kitchen with light blue cabinets, stainless steel appliances, and a wooden floor.
A bedroom with a bed, pillows, a lamp, and a painting on the wall.

Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
AED 408
AED 901 total
includes taxes & fees
13 Oct - 14 Oct
Amazing Renovated Historic Loft on Main Street
A modern kitchen with stainless steel appliances, white cabinetry, and a brick accent wall.
A bedroom with two beds, a TV, a desk, and a window.
A living room with a blue sofa, a round coffee table with a plant, and artwork on the wall.
A modern kitchen with white cabinets, a stainless steel refrigerator, and a wooden dining table with chairs.

Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
AED 397
AED 1,205 total
includes taxes & fees
14 Oct - 15 Oct
Historic Main St. Customs House Upstairs Apartment

Top Historic Main Street Hotel Reviews

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

8/10 Good
"Wonderful stay for a small bachelorette party. Had a wonderful time!"
Kara 1-night trip
Posted 2 days ago
Ameristar Casino Resort and Spa
Riverwood Retreat | Main Street 2BR

Riverwood Retreat | Main Street 2BR

10/10 Excellent
"Very Good apt! Near everything!"
Silvia 3-night trip
Posted 4 days ago
Riverwood Retreat | Main Street 2BR
The Oak & Aura Retreat

The Oak & Aura Retreat

10/10 Excellent
"The room was great. Very good location for the Oktoberfest. Very clean. We love the stay great communications."
Donna w. 2-night trip
Posted 2 weeks ago
The Oak & Aura Retreat
The St. Charles Guest House, lovely historic home, fun for families and groups

The St. Charles Guest House, lovely historic home, fun for families and groups

10/10 Excellent
"They were excellent hosts and great communication!! I highly recommend this house!"
Robert H. 4-night trip
Posted 1 month ago
The St. Charles Guest House, lovely historic home, fun for families and groups
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

8/10 Good
"Great accessibility to shops and restaurants"
Anonymous traveler 2-night trip
Posted 1 month ago
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
The Rustic Revival | Charming 2BR Retreat

The Rustic Revival | Charming 2BR Retreat

10/10 Excellent
"The Host ensured our needs were taken care. Perfect location!"
Phyllis N. 4-night trip
Posted 1 month ago
The Rustic Revival | Charming 2BR Retreat
Driftwood Den | Boho 2BR | Dog-Friendly

Driftwood Den | Boho 2BR | Dog-Friendly

10/10 Excellent
"Clean, easy parking, easy egress and ingress"
Rachel M. 5-night trip
Posted 2 months ago
Driftwood Den | Boho 2BR | Dog-Friendly
Main Street 2BR - Walk to Dining & Riverfront

Main Street 2BR - Walk to Dining & Riverfront

10/10 Excellent
"This is our new favorite property in St. Charles. Between the location, size of the space and the designated parking spot, we will definitely be staying here again!"
Billi G. 2-night trip
Posted 2 months ago
Main Street 2BR - Walk to Dining & Riverfront
The Foundry Flat | Industrial-Inspired 2-Bedroom

The Foundry Flat | Industrial-Inspired 2-Bedroom

10/10 Excellent
"Everything was exactly as described. St. Charles is an awesome place!"
Michael 2-night trip
Posted 2 months ago
The Foundry Flat | Industrial-Inspired 2-Bedroom

Other attractions near Historic Main Street

A person holding a guitar.
Photo by HA

Frontier Park

You can find out about the history of St. Charles with a visit to Frontier Park. Check out the shops and top-notch restaurants in this walkable area.
See properties
A steel bridge over a calm river with lush greenery and trees in the background.

Katy Trail

9.0/10 (158 reviews)
You can take time to visit Katy Trail during your travels to St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.
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First Missouri State Capitol Historic Site

8.2/10 (25 reviews)
You can learn about the history of St. Charles when you stop by First Missouri State Capitol Historic Site. Discover the top-notch restaurants and acclaimed theater scene in this family-friendly area.
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Missouri Artists on Main

You can spend an afternoon browsing the exhibits at Missouri Artists on Main in St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.
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Lewis & Clark Boathouse and Nature Center

8.8/10 (113 reviews)
You can spend time exploring the galleries in Lewis & Clark Boathouse and Nature Center during your travels in St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.
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Frenchtown Heritage Museum

You can spend time browsing the exhibits at Frenchtown Heritage Museum during your trip to St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.
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Lindenwood University

8.6/10 (183 reviews)
Walk around the campus at Lindenwood University during your stay in St. Charles. Experience the acclaimed theater scene and great live music in this family-friendly area.
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St Charles Convention Center

8.4/10 (223 reviews)
After visiting St Charles Convention Center, make a plan to see the other sights and activities in St. Charles. Discover the top-notch restaurants and great live music in this family-friendly area.
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Frequently asked questions

What's the area like around Historic Main Street?
Historic Main Street is located in St. Charles. This historic area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 103 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Historic Main Street?
Ameristar Casino Resort and Spa is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and a casino. It's located just a short 0.9 mi (1.4 km) from Historic Main Street. Another good option is Country Inn & Suites by Radisson, St. Charles Historic District, located just 0.6 mi (1 km) away.
How many hotels are there near Historic Main Street?
Expedia has 103 hotels and other accommodations within a mile from Historic Main Street.
If I need to cancel the hotel reservation for my stay near Historic Main Street, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the top deals on offer near Historic Main Street.
Where can I learn more about changing or cancelling my trip in the area near Historic Main Street?
For more information about rescheduling or cancelling your stay near Historic Main Street, click here.
What can I see and do near Historic Main Street?
Sights like First Missouri State Capitol Historic Site and Lewis & Clark Boathouse and Nature Center highlight some of the local culture. Create some family memories at Centene Community Ice Center and Kokomo Joe's Family Fun Center. At Hollywood Casino Amphitheatre, Missouri Artists on Main, and Historic Aircraft Restoration Museum, you'll experience some of the local culture.