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Find hotels near Historic Main Street, St. Louis from AED 298
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Our top choices for Historic Main Street hotels

Drury Plaza Hotel St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles1.8 km from Historic Main Street
9.6 out of 10, Exceptional, (1004)
The price is AED 422
AED 490 total
includes taxes & fees
11 Jan - 12 Jan

Country Inn & Suites by Radisson, St. Charles Historic District
Country Inn & Suites by Radisson, St. Charles Historic DistrictSt. Charles Historic District, 1 km from Historic Main Street
9.4 out of 10, Exceptional, (1001)
The price is AED 410
AED 471 total
includes taxes & fees
18 Jan - 19 Jan

Hampton Inn & Suites St. Charles Old Town Area
Hampton Inn & Suites St. Charles Old Town Area1.5 km from Historic Main Street
9.2 out of 10, Wonderful, (641)
The price is AED 399
AED 480 total
includes taxes & fees
25 Jan - 26 Jan

Embassy Suites by Hilton St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles2.1 km from Historic Main Street
8.8 out of 10, Excellent, (1004)
The price is AED 449
AED 516 total
includes taxes & fees
18 Jan - 19 Jan

Tru by Hilton St. Charles St. Louis, MO
Tru by Hilton St. Charles St. Louis, MO2.1 km from Historic Main Street
8.6 out of 10, Excellent, (776)
The price is AED 389
AED 450 total
includes taxes & fees
18 Jan - 19 Jan

8.4 out of 10, Very Good, (1013)
The price is AED 592
AED 752 total
includes taxes & fees
11 Jan - 12 Jan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Historic Main Street Hotel Reviews

Drury Plaza Hotel St. Louis St. Charles
10/10 Excellent
Hotels near other Historic Main Street attractions
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Hotels near popular St. Louis Attractions
- Hotels near First Missouri State Capitol Historic Site
- Hotels near Missouri Artists on Main
- Hotels near Ameristar Casino St. Charles
- Hotels near Mississippi River
- Hotels near Hollywood Casino Amphitheatre
- Hotels near St Charles Convention Center
- Hotels near Westport Plaza
- Hotels near Saint Louis Galleria Mall
- Hotels near Lindenwood University
- Hotels near St. Louis Premium Outlets
- Hotels near Family Arena
- Hotels near Hollywood Casino
- Hotels near Missouri River
- Hotels near The Factory
- Hotels near Lou Fusz Soccer Complex
- Hotels near Centene Community Ice Center
- Hotels near Mid Rivers Mall
- Hotels near Fast Lane Classic Cars
- Hotels near Blanche M. Touhill Performing Arts Center
- Hotels near SSM Health Rehabilitation Hospital
Hotels in top St. Charles Historic District neighborhoods
Other Hotels near Historic Main Street, St. Charles Historic District
- St. Charles Hotels
- Maryland Heights Hotels
- Chesterfield Hotels
- St. Peters Hotels
- Fenton Hotels
- Hazelwood Hotels
- Florissant Hotels
- Eureka Hotels
- Valley Park Hotels
- Bridgeton Hotels
- St. Ann Hotels
- Pacific Hotels
- O'Fallon Hotels
- Frontenac Hotels
- Earth City Hotels
- Wentzville Hotels
- Kirkwood Hotels
- Alton Hotels
- Brentwood Hotels
- Richmond Heights Hotels
More Hotel Options in Historic Main Street
- Adventure Hotels
- Business Hotels
- Casinos
- Family Hotels
- Golf Hotels
- Historic Hotels
- Hotel Wedding Venues
- Hotel with a Concierge
- Hotels with Bars
- Hotels with Free Parking
- Hotels with Hot Tubs
- Hotels with WiFi
- Hotels with a Pool
- Hotels with an Indoor Pool
- Hotels with smoking rooms
- Luxury Hotels
- Pet-friendly Hotels
- Resorts & Hotels with Spas
- Shopping Hotels
- Winery Hotels
Explore more hotels
- The Hare Suite at Divine Otter
- 3BR Historic St. Charles, MO-Walking distance to Main Street
- Western-Themed 2-Bedroom Hideout for Outlaws 204-2
- The Owl Suite at Divine Otter
- The Wild West Getaway- 204-1
- Scenic South Main Apartment with Breathtaking Views for 3 Guests
- The Buck Suite at Divine Otter
- Drury Plaza Hotel St. Louis St. Charles
- Hampton Inn & Suites St. Charles Old Town Area
- The Bear Suite at Divine Otter
- Charming Cottage on Main St. in Historic St. Charles! Jetted Tub, 2 Fireplaces!!
- The Fox Suite at Divine Otter




















































































