
Find hotels in South Central Houston, Houston
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Our top choices for South Central Houston hotels

InterContinental Houston by IHG
InterContinental Houston by IHG
The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum District
Houston Marriott Medical Center/Museum District
Houston Marriott Medical Center/Museum District
Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical Center
Hotel Zaza Houston Museum District
Hotel Zaza Houston Museum District
Sentral Forme Houston
Sentral Forme Houston
Downtowner Inns - Houston Downtown
Downtowner Inns - Houston Downtown
DoubleTree by Hilton Houston Medical Center Hotel & Suites
DoubleTree by Hilton Houston Medical Center Hotel & Suites
La Maison in Midtown an urban B&B
La Maison in Midtown an urban B&B
Americas Best Value Inn Medical Center Downtown
Americas Best Value Inn Medical Center Downtown
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Newly Built Modern 3 Bedroom Houston Home
Newly Built Modern 3 Bedroom Houston Home
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Hilton University of Houston
Hilton University of Houston
Southmore Boulevard Motel
Southmore Boulevard Motel
Scott Inn Suites - Downtown Houston
Scott Inn Suites - Downtown Houston
MorningSide Inn
MorningSide Inn
Wanderstay Houston Hostel
Wanderstay Houston Hostel
Downtown Houston 3BR Bachelorette Escape
Downtown Houston 3BR Bachelorette Escape
2-bedroom - Equipped Kitchen - Gated Parking
2-bedroom - Equipped Kitchen - Gated ParkingCompare popular hotels in South Central Houston
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only | 9.6 Exceptional 216 reviews | View | ||||||
![]() InterContinental Houston by IHG | 9.4 Exceptional 1,008 reviews | View | ||||||
![]() Downtowner Inns - Houston Downtown | 9.2 Wonderful 210 reviews | View | ||||||
![]() The Westin Houston Medical Center/Museum District | 9.2 Wonderful 1,167 reviews | View | ||||||
![]() Hotel Zaza Houston Museum District | 9.2 Wonderful 1,005 reviews | View |
Where to stay in South Central Houston

Downtown Houston
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria
Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

Texas Medical Center
Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.
Top South Central Houston Hotel Reviews



























































































