Find hotels in South Central Houston, Houston from AED 303

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Check prices for these dates

Next weekend
5 Jun - 7 Jun
In two weeks
12 Jun - 14 Jun

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Our top choices for South Central Houston hotels

Laptop workspace, blackout drapes, soundproofing, iron/ironing board

Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
South Central Houston
9.2 out of 10, Wonderful, (149 reviews)
"Great place. The staff is very friendly and the place is clean."
United States
Fernando
The price is AED 324
AED 380 total
includes taxes & fees
1 Jun - 2 Jun
Downtowner Inns - Houston Downtown
Terrace/patio

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
South Central Houston
8.4 out of 10, Very Good, (1,940 reviews)
"Great stay and clean room"
United States
Ethel
The price is AED 584
AED 688 total
includes taxes & fees
7 Jun - 8 Jun
Hilton Houston Plaza/Medical Center
Exterior detail

Sentral Forme Houston

Sentral Forme Houston
4.5 star property
South Central Houston
9.0 out of 10, Wonderful, (46 reviews)
"Very chic, very interesting room. Love this place"
United States
Chase
The price is AED 694
AED 920 total
includes taxes & fees
7 Jun - 8 Jun
Sentral Forme Houston
House, Smoking | 2 bedrooms

2-bedroom - Equipped Kitchen - Gated Parking

2-bedroom - Equipped Kitchen - Gated Parking
2.0 star property
South Central Houston
The price is AED 248
AED 2,171 total
includes taxes & fees
2 Jun - 3 Jun
2-bedroom - Equipped Kitchen - Gated Parking
Room, 1 King Bed, Smoking | Bathroom | Free toiletries, hair dryer, towels

Golden Motel Near Houston Medical Center

Golden Motel Near Houston Medical Center
2.5 star property
South Central Houston
2.0 out of 10, (2 reviews)
"Room smelt like cigarettes burnt wholes in the wall and bed sheet all 6 walls had stains toilet seat look like someone stood on it "
United States
Jacari
The price is AED 239
AED 303 total
includes taxes & fees
1 Jun - 2 Jun
Golden Motel Near Houston Medical Center
Standard Room, 1 King Bed | 1 bedroom, premium bedding, blackout drapes, free WiFi

Southmore Boulevard Motel

Southmore Boulevard Motel
2.0 star property
South Central Houston
5.6 out of 10, (238 reviews)
"I enjoyed my stay at this hotel."
United States
Tamela
The price is AED 299
AED 350 total
includes taxes & fees
1 Jun - 2 Jun
Southmore Boulevard Motel
Apartment, 2 Bedrooms | Living area | Smart TV, streaming services

Cozy 2BR Near NRG & Downtown FIFA World Cup

Cozy 2BR Near NRG & Downtown FIFA World Cup
3.0 star property
South Central Houston
The price is AED 354
AED 1,015 total
includes taxes & fees
2 Jun - 3 Jun
Cozy 2BR Near NRG & Downtown FIFA World Cup
Dinner served

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
South Central Houston
9.0 out of 10, Wonderful, (1,002 reviews)
"Nice and helpful staff, clean rooms, nice amenities "
United States
Andrea
The price is AED 625
AED 850 total
includes taxes & fees
6 Jun - 7 Jun
Houston Marriott Medical Center/Museum District
Breakfast, lunch and dinner served

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
South Central Houston
8.4 out of 10, Very Good, (595 reviews)
"was ok"
United States
Guillermo
The price is AED 440
AED 515 total
includes taxes & fees
7 Jun - 8 Jun
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Reception

Wanderstay Boutique Hotel

Wanderstay Boutique Hotel
3.0 star property
South Central Houston
9.8 out of 10, Exceptional, (76 reviews)
"Solo trip and it was a perfect location staff was nice and it was nice and clean!! Would stay there again. "
United States
Sharon
The price is AED 605
AED 707 total
includes taxes & fees
1 Jun - 2 Jun
Wanderstay Boutique Hotel
Reception

Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown
2.0 star property
South Central Houston
8.0 out of 10, Very Good, (1,002 reviews)
"Convenient location and comfortable room."
United States
Rogelio
The price is AED 305
AED 357 total
includes taxes & fees
1 Jun - 2 Jun
Americas Best Value Inn Medical Center Downtown
Lobby

Hilton University of Houston

Hilton University of Houston
3.5 star property
South Central Houston
9.0 out of 10, Wonderful, (949 reviews)
"The hotel was clean, staff were friendly and the location was perfect for our event. I will definitely stay there again. "
United States
Ricardo
The price is AED 535
AED 625 total
includes taxes & fees
8 Jun - 9 Jun
Hilton University of Houston
Outdoor pool, free cabanas, pool umbrellas

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,155 reviews)
"Clean room,restaurant exceptional,excellent staff."
United States
Craig
The price is AED 625
AED 778 total
includes taxes & fees
6 Jun - 7 Jun
The Westin Houston Medical Center/Museum District
House, Smoking | 1 bedroom

Houston Hideaway Near Dwntwn and City Attractions

Houston Hideaway Near Dwntwn and City Attractions
2.0 star property
South Central Houston
The price is AED 253
AED 1,798 total
includes taxes & fees
2 Jun - 3 Jun
Houston Hideaway Near Dwntwn and City Attractions
Premium bedding, pillowtop beds, minibar, in-room safe

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.2 out of 10, Wonderful, (1,006 reviews)
"Overall great hotel. Definitely will be staying here again. Shout out to the staff crew."
United States
Vincent
The price is AED 885
AED 1,206 total
includes taxes & fees
1 Jun - 2 Jun
Hotel Zaza Houston Museum District
Lobby

Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
South Central Houston
5.8 out of 10, (1,002 reviews)
"Perfect place for my family and I to stay when one of us has an appointment at MD Anderson. Super affordable and extremely close to the appointment locations. Stayed there 4 times with out any issues."
United States
Catherine
The price is AED 297
AED 349 total
includes taxes & fees
1 Jun - 2 Jun
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Exterior

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,002 reviews)
"I had a good stay here"
United States
Avwerosuoghene
The price is AED 606
AED 783 total
includes taxes & fees
7 Jun - 8 Jun
InterContinental Houston by IHG
Outdoor pool

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
South Central Houston
9.6 out of 10, Exceptional, (212 reviews)
"Beautiful place and wonderful management. Would definitely stay again! "
United States
Shelly
The price is AED 760
AED 945 total
includes taxes & fees
4 Jun - 5 Jun
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Exterior

La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B
3.5 star property
South Central Houston
9.8 out of 10, Exceptional, (574 reviews)
"We felt welcome from the moment we walked in. The owners are so hospitable and the place such a delight. Loved the generous breakfast and ambiance- great parking as well!"
United States
Carolina
The price is AED 731
AED 855 total
includes taxes & fees
5 Jun - 6 Jun
La Maison in Midtown an urban B&B
Full-size fridge, microwave, oven, stovetop

Luxury Med Center Fully Equipped King Sized Bed Condos

Luxury Med Center Fully Equipped King Sized Bed Condos
4.0 star property
South Central Houston
8.4 out of 10, Very Good, (92 reviews)
"Facility was nice. DRIFTRS, the management company, is really bad. We were there for 4 days. Upon arrival we noticed no toilet paper and half the light bulbs burned out. The place was so dark I needed a flashlight to use the kitchen. We reported these issues immediately. They told us to use kitchen paper towels as toilet paper and did not respond to all the burned out light bulbs. We woke up every morning with the apartment hot and stuffy. The NEST thermostat is programmed to continually...
United States
Gordon
The price is AED 513
AED 949 total
includes taxes & fees
30 Jun - 1 Jul
Luxury Med Center Fully Equipped King Sized Bed Condos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in South Central Houston

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Reception
Wanderstay Boutique Hotel
3.0 star property
9.8
Exceptional
76 reviews
View
Exterior
La Maison in Midtown an urban B&B
3.5 star property
9.8
Exceptional
574 reviews
View
Laptop workspace, blackout drapes, soundproofing, iron/ironing board
Downtowner Inns - Houston Downtown
2.0 star property
9.2
Wonderful
149 reviews
View
Premium bedding, pillowtop beds, minibar, in-room safe
Hotel Zaza Houston Museum District
4.5 star property
9.2
Wonderful
1,006 reviews
View
Exterior detail
Sentral Forme Houston
4.5 star property
9.0
Wonderful
46 reviews
View

Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most.

Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Gerald D. Hines Waterwall Park.

Houston_TexasChildrensHospital_553248635389801905_9

Texas Medical Center

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Photo by George Zimzores
Open Photo by George Zimzores

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.

Top South Central Houston Hotel Reviews

La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B

8/10 Good
"Joseph was the star of the place! He made the most delicious breakfast! The place is lovely, it just needs some deep cleaning. The carpet in our room was old and the outside of the bath tub was quite dirty. The light switches in the bedroom and bathroom need some cleaning. Over all it was a pleasant stay."
Ivonne 2-night trip
Posted 6 hours ago
La Maison in Midtown an urban B&B

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Frequently asked questions

What's it like in South Central Houston?
Travelers are sure to enjoy a stay in Houston's South Central Houston neighborhood. Looking for sights you might find in a travel guide about South Central Houston? Consider a visit to Houston Zoo while you're in the neighborhood.
What's the best accommodation in South Central Houston?
Based on our traveler data, Hotel Zaza Houston Museum District is one of the top choices for your stay in South Central Houston. This hotel offers a full-service spa and a restaurant. Other good options for your stay in the area include Hilton Houston Plaza/Medical Center and Sentral Forme Houston.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1197 hotels and other accommodations in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the best options available in South Central Houston.
Where can I learn more about changing or cancelling my trip to South Central Houston?
To access more information about changing or cancelling your trip to South Central Houston, go to https://www.expedia.com/service/.
What is there to do around this Houston neighborhood?
Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden, and Bagby Dog Park. Houston Zoo and Fertitta Center are some other stops to visit in the neighborhood. Toyota Center and Daikin Park are some favorite places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station, or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.