Photo by Delen Wong

Find hotels in Isla Santa María from AED 255

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Compare 205 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Fernandina Hotel & Spa Galápagos
3.0 star property
9.4 out of 10, Exceptional, (20)
"I enjoyed my stay very much"
United States
Mark
Fernandina Hotel & Spa Galápagos
Hotel Ninfa
3.5 star property
8.4 out of 10, Very Good, (213)
"Great"
United States
Aleksandr
Hotel Ninfa
Hotel el descanso del Guia
3.5 star property
8.8 out of 10, Excellent, (170)
"Excelente hotel y personal"
Spain
leonel bladimir
Hotel el descanso del Guia
Galapagos Dreams
3.0 star property
8.8 out of 10, Excellent, (123)
"We stayed for 4 days was very good, the breakfast was delicious and also we booked the activities with them, everything was excellent "
United States
esperanza
The price is AED 304
AED 335 total
1 Nov - 2 Nov
Galapagos Dreams
Posada del Mar
3.0 star property
9.8 out of 10, Exceptional, (205)
"Great location. Friendly staff. "
United States
Debbie
The price is AED 255
AED 255 total
1 Nov - 2 Nov
Posada del Mar
Hotel Cucuve
4.0 star property
10.0 out of 10, Exceptional, (266)
"Great service, friendly staff, comfy bed, delicious breakfast, close to town center….helpful Ana…. Excellent stay "
United States
kat
The price is AED 776
AED 857 total
4 Nov - 5 Nov
Hotel Cucuve
Twin Hotel Galapagos
3.0 star property
8.4 out of 10, Very Good, (44)
"This hotle is fantastic lovely people that work here Very helpful with booking tours ect . To rooms are so fantastic, comfortable bed can’t get any better and good breakfast."
Canada
Chelsea
The price is AED 306
AED 306 total
5 Nov - 6 Nov
Twin Hotel Galapagos
Angermeyer Waterfront Inn
3.5 star property
9.4 out of 10, Exceptional, (122)
"Staff was very friendly and professional. They helped us with everything we asked for. "
United States
Ormond
The price is AED 862
AED 948 total
7 Nov - 8 Nov
Angermeyer Waterfront Inn
Hotel La Isla
3.5 star property
9.6 out of 10, Exceptional, (63)
"Relatively new hotel by a family who is passionate about hospitality. Huge rooms, elegantly appointed, and the best bed I’ve ever slept in. Unusual for a rather downscale town, but still felt authentic to the surroundings. Beautiful public spaces on all floors with scenic views. And a genuinely warm staff. "
United States
Edward
Hotel La Isla
Hostal Sir Francis Drake
2.5 star property
7.4 out of 10, Good, (72)
"Great location!"
United States
John
Hostal Sir Francis Drake
White House Galapagos
2.5 star property
9.0 out of 10, Wonderful, (96)
"The staff were wonderful. Off the main drag by a few blocks . "
Canada
catherine
White House Galapagos
Maidith Galapagos Inn
3.0 star property
10.0 out of 10, Exceptional, (98)
"Great location. Helpful owner and really friendly. Good breakfast and even did us a takeaway when we had to leave for an early ferry. Would stay again"
United Kingdom
Shelley
The price is AED 463
AED 463 total
15 Nov - 16 Nov
Maidith Galapagos Inn
Hostal North Seymour
3.0 star property
8.6 out of 10, Excellent, (141)
"Perfect location just a 5 minute walk to the dock. The staff were really helpful, sent an email with instructions on how to get to the hotel frombthe airport and arranged my taxi back to the Baltra ferry for an early flight."
United Kingdom
Gareth
Hostal North Seymour
Galapagos Chalet
2.5 star property
4.0 out of 10, (1)
"After we finally got checked in, turned the AC on and it was not cold. Owner told me it would cool down and to let her know if I didn't need it "cold like hers (friend's room) I would be fine but I could switch it in the morning. Let me be clear, the AC did not work AT ALL and when we returned it was hotter in the room than outside at 9pm. Couldn't open the windows or doors because the of the mosquitoes. The owner was not on site, so I ended up having to share the room with my friend instead of...
United States
Anonymous traveler
Galapagos Chalet
Plaza Luna Suites
3.0 star property
9.8 out of 10, Exceptional, (29)
"This hotel great location and employees are awesome, wonderful, nice and very professional friendly. This hotel is a gem in Puerto Ayora "
United States
Jorge A.
Plaza Luna Suites
Hotel Coloma Galapagos
3.0 star property
9.4 out of 10, Exceptional, (187)
"wonderful room and convenient location in puerta Ayora Small issue with noisy bathroom fan but I would recommend it "
United States
richard
Hotel Coloma Galapagos
Blu Galapagos Sustainable Waterfront Lodge
4.0 star property
8.8 out of 10, Excellent, (120)
"We had a great stay at Blu Galapagos. Loved the location and our room was perfect - Great view, well maintained and had a king bed. Even if the description says queen bed and the picture looks like a king, you can trust the picture. Morning breakfast with iguanas and seals, and all day Galapagos coffee availability made this stay special. "
United States
Doreen
The price is AED 700
AED 770 total
30 Nov - 1 Dec
Blu Galapagos Sustainable Waterfront Lodge
Hotel Santa Fe
4.0 star property
9.6 out of 10, Exceptional, (14)
"Beautiful hotel, with amazing staff, and great location "
United States
Steven
The price is AED 681
AED 749 total
14 Nov - 15 Nov
Hotel Santa Fe
Hotel La Casa de Judy
3.0 star property
9.0 out of 10, Wonderful, (158)
"The staff was nice and friendly. They were accommodating to our needs. They offered helpful suggestions to places and food locations nearby. Recommend coming here again."
United States
Marcela Estefania Pasquel De La
The price is AED 250
AED 335 total
4 Nov - 5 Nov
Hotel La Casa de Judy
Grand Hotel Leon Marino Galapagos
3.0 star property
8.6 out of 10, Excellent, (12)
"Spacious room with comfortable beds, effective air-con, and fast wifi. Just a short walk to the pier, shops and restaurants. Quiet, clean and comfortable. Tasty breakfast. Helpful staff."
United States
Anonymous traveler
The price is AED 324
AED 324 total
30 Nov - 1 Dec
Grand Hotel Leon Marino Galapagos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Isla Santa María attractions

Learn more about Isla Santa María

Head to sights like Galápagos National Park and Post Office Bay as you discover Isla Santa María.

I've been spotted! A family of marine iguanas auditioning for meerkat manor #LifeAtExpedia
Photo by Delen Wong
Open Photo by Delen Wong

Top Isla Santa María Hotel Reviews

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Frequently asked questions

Where is the best place for a stay in Isla Santa María?
Located 38.3 mi (61.7 km) from the heart of Isla Santa María, Hotel Fiesta is a top choice for your stay based on our traveler data. Other good choices for your trip to the area are Finch Bay Galapagos Hotel and Capitan Max B&B. See all available top hotels, or vacation rentals in Isla Santa María.
What are some of the best vacation rentals that Isla Santa María has to offer?
Villa Galapagos: This vacation home rental near Isla Santa María is located near the beach and offers a private yard, air-conditioning, and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Isla Santa María.
If I need to cancel my hotel reservation in Isla Santa María, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Isla Santa María.
Where can I learn more about changing or cancelling my trip to Isla Santa María?
For more details about updating your trip to Isla Santa María or cancelling it, click here.
What is staying in Isla Santa María like?
Travelers to Isla Santa María will find plenty to explore and enjoy. There are 205 hotels and other accommodations in larger region. Find out more about Isla Santa María.
What should I see while I'm in Isla Santa María?
Favorite places to visit include Galápagos National Park, Post Office Bay, and Punta Suarez. Check out what more to see and do in Expedia's Isla Santa María guide.
What's the weather like in Isla Santa María?
The hottest months are usually March and February with an average temp of 79°F, while the coldest months are September and October with an average of 72°F. Average annual precipitation for Isla Santa María is 13 inches.