A forest stream with moss-covered rocks and sunlight filtering through the trees.

Vacation Homes in Jackson County

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Check prices for these dates

In two weeks
28 Aug - 30 Aug
In two months
9 Oct - 11 Oct
In three months
6 Nov - 8 Nov
In four months
4 Dec - 6 Dec

Top Cities in Jackson County

A historic building with 'LIBERTY' on the facade, a vintage car parked in front, and various signs including 'VISIONS' and 'DENTAL'.
Vacation HomesVacation Homes

Makanda

Makanda

Our top choices for Jackson County vacation homes

Property grounds

1. Lakefront, amazing views, boat rentals available

Lakefront, amazing views, boat rentals available
Creal Springs
9.6 out of 10, Exceptional, (49 reviews)
"Wonderful place so beautiful Thank you "
United States
Tammy R.
Lakefront, amazing views, boat rentals available
TV

2. * On the Wine Trail * Hot Tub * Wi-Fi *

* On the Wine Trail * Hot Tub * Wi-Fi *
Alto Pass
9.8 out of 10, Exceptional, (252 reviews)
"Cute, quaint, and quiet town! 20 mins from great hiking and minutes away from winery and bourbon bar."
United States
Jean S.
* On the Wine Trail * Hot Tub * Wi-Fi *
Exterior

3. “Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau
Cape Girardeau
10.0 out of 10, Exceptional, (44 reviews)
"Spectacular place and great host! Highly recommend!"
United States
Eric P.
“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau
Coffee/tea maker, fridge, microwave, oven

4. Wine Trail, Cozy Cabin plus hot tub

Wine Trail, Cozy Cabin plus hot tub
Cobden
9.8 out of 10, Exceptional, (124 reviews)
"This was a perfect stay for us! Process was easy, home was very clean and welcoming, managers responded quickly with any questions!"
United States
Trisha S.
Wine Trail, Cozy Cabin plus hot tub
Outdoor dining

5. Lake of Egypt waterfront home

Lake of Egypt waterfront home
Creal Springs
10.0 out of 10, Exceptional, (3 reviews)
"The house was very nice and spacious. The water access was also great to bring a boat. the Host was also very nice and accommodating. The views a beautiful from the deck!"
United States
chase b.
Lake of Egypt waterfront home
Interior

6. * Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *

* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *
Alto Pass
10.0 out of 10, Exceptional, (114 reviews)
"Fantastic place. Definitely will try to get the “back” Unit with the outside amenities."
United States
Jesse C.
* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *
Dining

7. Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space
Cape Girardeau
10.0 out of 10, Exceptional, (159 reviews)
"Nice place. I’d stay there again. "
United States
John H.
Serenity South -- Gardens, River-Views, and Refreshing Space
Interior

8. 3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau
Cape Girardeau
9.8 out of 10, Exceptional, (27 reviews)
"We had a great stay. Great location as well "
United States
Tracy H.
3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau
Property grounds

9. Miller lakehouse. Pontoon available to rent

Miller lakehouse. Pontoon available to rent
Marion
9.8 out of 10, Exceptional, (139 reviews)
"Perfect quiet place right on the lake. Exactly what we were looking for. Will book again!"
United States
Sheryl R.
Miller lakehouse. Pontoon available to rent
Interior

10. Our Most Popular Lakefront Home

Our Most Popular Lakefront Home
Carbondale
10.0 out of 10, Exceptional, (51 reviews)
"Excellent stay"
United States
Tommie V.
Our Most Popular Lakefront Home
Property grounds

11. WATERFRONT Vacation! {3 bed 2 bath. Sleeps 13}

WATERFRONT Vacation! {3 bed 2 bath. Sleeps 13}
Goreville
9.8 out of 10, Exceptional, (80 reviews)
"Great location very clean and a great size for a family trip!!!!!!"
United States
justin e.
WATERFRONT Vacation! {3 bed 2 bath. Sleeps 13}
Exterior

12. Owl's Nest 2- With 2 floors to spread out, bring the whole gang! Including pets

Owl's Nest 2- With 2 floors to spread out, bring the whole gang! Including pets
Carbondale
9.6 out of 10, Exceptional, (4 reviews)
"We enjoyed the place! Owner was super helpful!"
United States
Stephanie H.
Owl's Nest 2- With 2 floors to spread out, bring the whole gang! Including pets
Smart TV, fireplace

13. Quaint, Beautiful Home next to SEMO and Hospital

Quaint, Beautiful Home next to SEMO and Hospital
Cape Girardeau
9.8 out of 10, Exceptional, (51 reviews)
"Would stay here again!"
United States
Michelle C.
Quaint, Beautiful Home next to SEMO and Hospital
Property grounds

14. Relaxing lake front home with beautiful view on the lake, sleeps 7.

Relaxing lake front home with beautiful view on the lake, sleeps 7.
Creal Springs
8.8 out of 10, Excellent, (56 reviews)
"Me and the kids loved our stay here!"
United States
Kara B.
Relaxing lake front home with beautiful view on the lake, sleeps 7.
Interior

15. 5 Star Cabin LUXURY AMMENITIES W/POOL HTUB close to WINE TRAIL, HIKING, FISHING

5 Star Cabin LUXURY AMMENITIES W/POOL HTUB close to WINE TRAIL, HIKING, FISHING
Murphysboro
10.0 out of 10, Exceptional, (27 reviews)
"This was a beautiful house with great amnesties. The pond on the property was filled with bass and bluegill and we had a great time fishing. The house was conveniently located near town and was setup nicely for a relaxing weekend."
United States
Joshua T.
5 Star Cabin LUXURY AMMENITIES W/POOL HTUB close to WINE TRAIL, HIKING, FISHING
Property grounds

16. Lakefront at Lake of Egypt sleeps 10! Dock/2 kayaks 2 paddleboards!

Lakefront at Lake of Egypt sleeps 10! Dock/2 kayaks 2 paddleboards!
Creal Springs
9.2 out of 10, Wonderful, (154 reviews)
"Wonderful lake views and amazing sunsets!"
United States
Jeanette Y.
Lakefront at Lake of Egypt sleeps 10! Dock/2 kayaks 2 paddleboards!
TV, fireplace, books

17. Spacious 3 bedroom, 2 full baths, hot tub, fireplace, full kitchen, outside deck

Spacious 3 bedroom, 2 full baths, hot tub, fireplace, full kitchen, outside deck
Anna
9.8 out of 10, Exceptional, (49 reviews)
"Great place. We would definitely stay there again. "
United States
Brett L.
Spacious 3 bedroom, 2 full baths, hot tub, fireplace, full kitchen, outside deck
Property grounds

18. Relaxing escape or fishing getaway! Central location for hiking, wineries, fun

Relaxing escape or fishing getaway! Central location for hiking, wineries, fun
Goreville
10.0 out of 10, Exceptional, (322 reviews)
"It was a great location and beautiful property!! I would recommend this to everyone I know looking for a relaxing getaway spot. Very clean, quiet and right on the lake."
United States
Terry M.
Relaxing escape or fishing getaway! Central location for hiking, wineries, fun
Smart TV, fireplace

19. "Adventure's Rest - Hot Tub, Wine Trail - Fire Pit - Grill, Secluded & Relaxing

"Adventure's Rest - Hot Tub, Wine Trail - Fire Pit - Grill, Secluded & Relaxing
Makanda
10.0 out of 10, Exceptional, (21 reviews)
"This was a great place to stay! The setting was beautiful, and Bob was such a great host! We will definitely try to stay again in the future!"
United States
Nita L.
"Adventure's Rest - Hot Tub, Wine Trail - Fire Pit - Grill, Secluded & Relaxing
Coffee/tea maker, fridge, microwave, oven

20. Beautiful Lake Getaway

Beautiful Lake Getaway
Marion
10.0 out of 10, Exceptional, (25 reviews)
"One of the best spots on the lake. Location is perfect and house is always clean. Will definitely be staying here again next summer. "
United States
Kory R.
Beautiful Lake Getaway
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Jackson County Hotel Reviews

Drury Inn & Suites Marion

Drury Inn & Suites Marion

10/10 Excellent
"Everything was great about this hotel from the staff to the rooms. Pool was great. We will be back!"
Connie 1-night trip
Posted 6 hours ago
Drury Inn & Suites Marion

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