Find Family Hotels in Lake City, SC

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Check availability on Lake City Family Hotels

Tonight
7 Dec - 8 Dec
Tomorrow
8 Dec - 9 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Top Lake City Family Hotels

Desk, iron/ironing board, free WiFi, bed sheets
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 star property
Florence
6.8 out of 10, (1003)
"Clean rooms and wonderful staff "
United States
Rita
The price is AED 228
AED 255 total
includes taxes & fees
8 Dec - 9 Dec
Days Inn by Wyndham Florence Near Civic Center
Premium bedding, in-room safe, desk, iron/ironing board
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 star property
Florence
7.8 out of 10, Good, (1255)
"Room was spotless, bed extremely comfortable and staff was very helpful and courteous. Would DEFINITELY stay there again. "
United States
Tim
The price is AED 281
AED 314 total
includes taxes & fees
5 Jan - 6 January 2026
Quality Inn & Suites Florence Civic Center
Property amenity
Aloft Florence

Aloft Florence

3.0 star property
Florence
8.6 out of 10, Excellent, (246)
"good stay "
Canada
Joanne
The price is AED 371
AED 415 total
includes taxes & fees
11 Dec - 12 Dec
Aloft Florence
Fridge, microwave, oven, stovetop
Walking distance from one of South Carolina's top Medical centers.

Walking distance from one of South Carolina's top Medical centers.

Florence
9.8 out of 10, Exceptional, (42)
"The house was beautiful. We would stay there again!!"
United States
Stephanie L.
The price is AED 493
AED 848 total
includes taxes & fees
8 Dec - 9 Dec
Walking distance from one of South Carolina's top Medical centers.
Desk, laptop workspace, free cribs/infant beds, free WiFi
Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2.0 star property
Florence
6.8 out of 10, (1002)
"Small Budget motel room "
United States
Hi Tech Travel and Tours
The price is AED 206
AED 231 total
includes taxes & fees
10 Dec - 11 Dec
Red Roof Inn Florence - Civic Center
Game room
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Florence
10.0 out of 10, Exceptional, (35)
"Perfect stay for our family wedding weekend!! Home was immaculate and a perfect layout! Host has thought of everything you may need during your stay from extra linens to a fully stocked kitchen. Awesome location and super nice neighborhood!"
United States
Cathy D.
The price is AED 754
AED 959 total
includes taxes & fees
9 Dec - 10 Dec
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Lake City Hotel Reviews

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

10/10 Excellent
"Very good breakfast & convenient location"
Diedre 1-night trip
Posted 5 days ago
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

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Frequently asked questions

What's Lake City like for family-friendly vacations?
The budget-friendly destination of Lake City is a good choice if you've been thinking about a trip with your kids. The lake views, parks, and restaurants are just some of the things that make this an attractive family vacation spot. Take to the air and fly into Florence, SC (FLO-Florence Regional), which is located 22.2 mi (35.8 km) from the city center.
When's the best time to book a family-friendly vacation in Lake City?
The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 51°F. Average annual precipitation for Lake City is 53 inches.
What's there to see and do with your family in Lake City?
Lynches Lake Historical Society, Ronald E. McNair Life History Center, and The Bean Market are interesting attractions you and your family will enjoy exploring while you are staying in Lake City. Make sure you have lots of time for activities like Lions Park and Moore Farms Botanical Garden.