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Our top choices for Florence, SC (FLO-Florence Regional) hotels

Hyatt Place Florence Downtown
Hyatt Place Florence Downtown3.5 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,009 reviews)
The price is AED 440
AED 493 total
includes taxes & fees
2 Jul - 3 Jul

Hotel Florence, Tapestry Collection by Hilton
Hotel Florence, Tapestry Collection by Hilton3.6 km from Florence, SC (FLO-Florence Regional)
8.8 out of 10, Excellent, (639 reviews)
The price is AED 467
AED 523 total
includes taxes & fees
1 Jul - 2 Jul

Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SC8 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (2,293 reviews)
The price is AED 328
AED 367 total
includes taxes & fees
14 Jun - 15 Jun

Hampton Inn & Suites Florence-North-I-95
Hampton Inn & Suites Florence-North-I-958.2 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (922 reviews)
The price is AED 423
AED 474 total
includes taxes & fees
16 Jun - 17 Jun

Affordable Suites Florence
Affordable Suites Florence9.7 km from Florence, SC (FLO-Florence Regional)
9.2 out of 10, Wonderful, (173 reviews)
The price is AED 234
AED 262 total
includes taxes & fees
6 Jun - 7 Jun

Comfort Inn & Suites Florence Center Area
Comfort Inn & Suites Florence Center Area9.6 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,298 reviews)
The price is AED 432
AED 484 total
includes taxes & fees
21 Jun - 22 Jun

Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florence8 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (2,680 reviews)
The price is AED 258
AED 289 total
includes taxes & fees
7 Jun - 8 Jun

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG8.3 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (1,006 reviews)
The price is AED 466
AED 522 total
includes taxes & fees
14 Jun - 15 Jun

Residence Inn Marriott Florence
Residence Inn Marriott Florence9.9 km from Florence, SC (FLO-Florence Regional)
8.8 out of 10, Excellent, (552 reviews)
The price is AED 450
AED 504 total
includes taxes & fees
11 Jun - 12 Jun

Spark by Hilton Florence North I-95, SC
Spark by Hilton Florence North I-95, SC8 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very Good, (141 reviews)
The price is AED 298
AED 348 total
includes taxes & fees
21 Jun - 22 Jun

Hilton Garden Inn Florence
Hilton Garden Inn Florence9.9 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (325 reviews)
The price is AED 476
AED 533 total
includes taxes & fees
21 Jun - 22 Jun

Aloft by Marriott Florence
Aloft by Marriott Florence10.2 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (340 reviews)
The price is AED 393
AED 440 total
includes taxes & fees
10 Jun - 11 Jun

Quality Inn & Suites Florence Civic Center
Quality Inn & Suites Florence Civic Center10.2 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (174 reviews)
The price is AED 314
AED 352 total
includes taxes & fees
7 Jun - 8 Jun

Hampton Inn & Suites Florence Center
Hampton Inn & Suites Florence Center9.9 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (894 reviews)
The price is AED 404
AED 452 total
includes taxes & fees
21 Jun - 22 Jun

Comfort Suites Florence I-95
Comfort Suites Florence I-958.3 km from Florence, SC (FLO-Florence Regional)
8.2 out of 10, Very Good, (1,005 reviews)
The price is AED 318
AED 385 total
includes taxes & fees
6 Jul - 7 Jul

SpringHill Suites by Marriott Florence
SpringHill Suites by Marriott Florence9.8 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very Good, (1,003 reviews)
The price is AED 335
AED 375 total
includes taxes & fees
21 Jun - 22 Jun

Homewood Suites by Hilton Florence
Homewood Suites by Hilton Florence10.8 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very Good, (696 reviews)
The price is AED 389
AED 450 total
includes taxes & fees
6 Jul - 7 Jul

Best Western Inn
Best Western Inn7.2 km from Florence, SC (FLO-Florence Regional)
7.8 out of 10, Good, (1,003 reviews)
The price is AED 327
AED 366 total
includes taxes & fees
7 Jun - 8 Jun

La Quinta Inn & Suites by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florence8.1 km from Florence, SC (FLO-Florence Regional)
7.8 out of 10, Good, (1,590 reviews)
The price is AED 309
AED 346 total
includes taxes & fees
7 Jun - 8 Jun

Courtyard by Marriott Florence
Courtyard by Marriott Florence9.8 km from Florence, SC (FLO-Florence Regional)
7.8 out of 10, Good, (746 reviews)
The price is AED 372
AED 416 total
includes taxes & fees
21 Jun - 22 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels close to Florence, SC (FLO-Florence Regional)
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Hyatt Place Florence Downtown | 9.0 Wonderful 1,009 reviews | View | ||||||
![]() Hotel Florence, Tapestry Collection by Hilton | 8.8 Excellent 639 reviews | View | ||||||
![]() Park Inn by Radisson Florence, SC | 9.0 Wonderful 2,293 reviews | View | ||||||
![]() Hampton Inn & Suites Florence-North-I-95 | 9.0 Wonderful 922 reviews | View | ||||||
![]() Affordable Suites Florence | 9.2 Wonderful 173 reviews | View |
Top Florence Regional Hotel Reviews

Spark by Hilton Florence North I-95, SC
8/10 Good
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Hotels Close to Nearby Airports
Hotels near popular Florence Attractions
Hotel options around Florence Regional
- Pineapple House: Historic. Southern Charm. Walk Downtown.
- Howard Johnson by Wyndham Florence
- Spark by Hilton Florence North I-95, SC
- 3-bedroom mobile home in Florence, SC
- Super 8 by Wyndham Florence
- Clarion Inn & Suites Florence - Darlington
- Best Western Inn
- La Quinta Inn & Suites by Wyndham Florence
- Luxury stay at 4 bedroom house
- Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
- Motel 6 Florence, SC
- Hampton Inn & Suites Florence-North-I-95
- Days Inn by Wyndham Florence/I-95 North
- MainStay Suites Florence - Darlington
- Quality Inn & Suites Florence Civic Center
- Econo Lodge Florence - Darlington
- Tru by Hilton Florence I-95
- Comfort Suites Florence I-95
- Suburban Studios Florence I-95
- Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.








































































