Find hotels near Lewis and Clark Interpretive Center, St. Louis from AED 262
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Compare 1,956 hotels close to Lewis and Clark Interpretive Center with room rates, reviews, and availability. Most hotels are fully refundable.

Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
6.2 km from Lewis and Clark Interpretive Center
9.2 out of 10, Wonderful, (488)
The price is AED 411
AED 457 total
includes taxes & fees
15 Dec - 16 Dec

Bel Air Motel
6.3 km from Lewis and Clark Interpretive Center
8.6 out of 10, Excellent, (195)
The price is AED 290
AED 355 total
includes taxes & fees
10 Dec - 11 Dec

Holiday Inn Express & Suites Edwardsville by IHG
10.9 km from Lewis and Clark Interpretive Center
9.2 out of 10, Wonderful, (817)
The price is AED 426
AED 490 total
includes taxes & fees
4 Jan - 5 January 2026

Best Western Plus Pontoon Beach
6.8 km from Lewis and Clark Interpretive Center
8.6 out of 10, Excellent, (796)
The price is AED 314
AED 348 total
includes taxes & fees
14 Dec - 15 Dec

TownePlace Suites by Marriott St. Louis Edwardsville, IL
10.9 km from Lewis and Clark Interpretive Center
9.0 out of 10, Wonderful, (193)
The price is AED 621
AED 714 total
includes taxes & fees
19 Dec - 20 Dec

Drury Inn & Suites St. Louis Collinsville
15.4 km from Lewis and Clark Interpretive Center
9.6 out of 10, Exceptional, (1001)
The price is AED 360
AED 414 total
includes taxes & fees
14 Dec - 15 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Lewis and Clark Interpretive Center Hotel Reviews

St. Louis Union Station Hotel, Curio Collection by Hilton
10/10 Excellent
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