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Check prices for these dates

This weekend
25 Sep - 27 Sep
Next weekend
2 Oct - 4 Oct

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Our top choices for Main Street Fort Pierce hotels

Outdoor spa tub

1. Hutchinson Island Hotel

Hutchinson Island Hotel
2.5 star property
3.1 km from Main Street Fort Pierce
8.2 out of 10, Very good, (1,367 reviews)
"Great place to stay and enjoy the beach!"
United States
Kathleen
The price is AED 395
AED 513 total
includes taxes & fees
22 Oct - 23 Oct
Hutchinson Island Hotel
WiFi (free), individually decorated, individually furnished, bed sheets

2. Redfinn Inn

Redfinn Inn
2.5 star property
0.7 km from Main Street Fort Pierce
6.4 out of 10, (418 reviews)
"Great newish renovated property, super clean very quiet excellent staff!"
United States
Robert
The price is AED 182
AED 204 total
includes taxes & fees
27 Sep - 28 Sep
Redfinn Inn
Lobby

3. La Quinta Inn & Suites by Wyndham Ft. Pierce

La Quinta Inn & Suites by Wyndham Ft. Pierce
3.0 star property
7.9 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1,000 reviews)
"Very clean friendly staff good breakfast"
United States
riad
The price is AED 323
AED 362 total
includes taxes & fees
27 Sep - 28 Sep
La Quinta Inn & Suites by Wyndham Ft. Pierce
Lobby

4. Hampton Inn & Suites Ft. Pierce

Hampton Inn & Suites Ft. Pierce
2.5 star property
7.9 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (1,001 reviews)
"EVERYTHING WAS EXCELLENT"
United States
ROOSEVELT
The price is AED 358
AED 401 total
includes taxes & fees
11 Oct - 12 Oct
Hampton Inn & Suites Ft. Pierce
Restaurant

5. Days Inn & Suites by Wyndham Fort Pierce Midtown

Days Inn & Suites by Wyndham Fort Pierce Midtown
2.0 star property
4.5 km from Main Street Fort Pierce
7.0 out of 10, Good, (1,002 reviews)
"Good value"
United States
Cynthia
The price is AED 222
AED 248 total
includes taxes & fees
27 Sep - 28 Sep
Days Inn & Suites by Wyndham Fort Pierce Midtown
Lobby lounge

6. Fairfield Inn & Suites by Marriott Fort Pierce

Fairfield Inn & Suites by Marriott Fort Pierce
3.0 star property
7.7 km from Main Street Fort Pierce
8.8 out of 10, Excellent, (1,000 reviews)
"Nice hotel, good location"
United States
Wilmer
The price is AED 340
AED 381 total
includes taxes & fees
1 Oct - 2 Oct
Fairfield Inn & Suites by Marriott Fort Pierce
Terrace/patio

7. Home2 Suites by Hilton Ft. Pierce I-95

Home2 Suites by Hilton Ft. Pierce I-95
3.0 star property
7.8 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (271 reviews)
"Nice little breakfast...very clean and easy check in and check out..."
United States
JERRY
The price is AED 419
AED 469 total
includes taxes & fees
11 Oct - 12 Oct
Home2 Suites by Hilton Ft. Pierce I-95
Lobby

8. Holiday Inn Express Hotel & Suites Fort Pierce West by IHG

Holiday Inn Express Hotel & Suites Fort Pierce West by IHG
2.5 star property
8.3 km from Main Street Fort Pierce
8.8 out of 10, Excellent, (889 reviews)
"We have stayed at this hotel before. We like the facility and staff"
United States
walter
The price is AED 360
AED 403 total
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express Hotel & Suites Fort Pierce West by IHG
Deluxe Room, 1 King Bed, Accessible, Non Smoking (Roll-In Shower) | Desk, laptop workspace, blackout drapes, cribs (free)

9. Red Roof Inn Ft Pierce

Red Roof Inn Ft Pierce
2.0 star property
4.6 km from Main Street Fort Pierce
7.2 out of 10, Good, (816 reviews)
"Nice place to stay "
United States
Rhonise
The price is AED 264
AED 296 total
includes taxes & fees
27 Sep - 28 Sep
Red Roof Inn Ft Pierce
Lobby

10. Rodeway Inn Fort Pierce US Highway 1

Rodeway Inn Fort Pierce US Highway 1
2.0 star property
2.9 km from Main Street Fort Pierce
6.8 out of 10, (124 reviews)
"Clean room, convenient location"
United States
Natalia
The price is AED 265
AED 297 total
includes taxes & fees
25 Oct - 26 Oct
Rodeway Inn Fort Pierce US Highway 1
Front of property

11. At Home Inn

At Home Inn
2.5 star property
8.2 km from Main Street Fort Pierce
8.0 out of 10, Very good, (1,301 reviews)
"Love the hotel"
United States
Eric
The price is AED 207
AED 232 total
includes taxes & fees
23 Oct - 24 Oct
At Home Inn
Beach/ocean view

12. The Royal Inn Beach Hotel Hutchinson Island

The Royal Inn Beach Hotel Hutchinson Island
2.5 star property
3.8 km from Main Street Fort Pierce
7.2 out of 10, Good, (1,000 reviews)
"My go-to hotel when I need a place to get away!"
United States
Taylor
The price is AED 383
AED 488 total
includes taxes & fees
3 Oct - 4 Oct
The Royal Inn Beach Hotel Hutchinson Island
Pillowtop beds, desk, blackout drapes, iron/ironing board

13. Comfort Suites Fort Pierce I-95

Comfort Suites Fort Pierce I-95
2.5 star property
7.7 km from Main Street Fort Pierce
7.8 out of 10, Good, (965 reviews)
"Clean rooms, friendly staff"
United States
Marina
The price is AED 317
AED 355 total
includes taxes & fees
30 Sep - 1 Oct
Comfort Suites Fort Pierce I-95
Property grounds

14. Road Runner Travel Resort - Caravan Park

Road Runner Travel Resort - Caravan Park
2.5 star property
7 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (102 reviews)
"Our family had an amazing stay, the pool was fun, everyone was friendly and our cabin was the perfect fit. "
United States
Benjamin
The price is AED 643
AED 720 total
includes taxes & fees
25 Sep - 26 Sep
Road Runner Travel Resort - Caravan Park
Lobby

15. Days Inn & Suites by Wyndham Fort Pierce I-95

Days Inn & Suites by Wyndham Fort Pierce I-95
2.5 star property
7.8 km from Main Street Fort Pierce
7.4 out of 10, Good, (1,000 reviews)
"The staff was excellent"
United States
Carlton
The price is AED 217
AED 243 total
includes taxes & fees
27 Sep - 28 Sep
Days Inn & Suites by Wyndham Fort Pierce I-95
Outdoor pool, sun loungers

16. Best Western Port St. Lucie

Best Western Port St. Lucie
2.5 star property
14 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1,001 reviews)
"Clean comfortable beds I would come back"
United States
Andrew
The price is AED 314
AED 352 total
includes taxes & fees
8 Oct - 9 Oct
Best Western Port St. Lucie
Free daily on-the-go breakfast

17. Hampton Inn & Suites Port St. Lucie, West

Hampton Inn & Suites Port St. Lucie, West
2.5 star property
17.4 km from Main Street Fort Pierce
9.0 out of 10, Wonderful, (1,004 reviews)
"I will definitely be staying there again!!"
United States
Nicholette
The price is AED 313
AED 351 total
includes taxes & fees
10 Oct - 11 Oct
Hampton Inn & Suites Port St. Lucie, West
Lobby

18. Sleep Inn Fort Pierce I-95

Sleep Inn Fort Pierce I-95
2.5 star property
7.9 km from Main Street Fort Pierce
7.6 out of 10, Good, (911 reviews)
"Staff was very friendly and rooms were clean"
United States
Charity
The price is AED 231
AED 259 total
includes taxes & fees
1 Oct - 2 Oct
Sleep Inn Fort Pierce I-95
On the beach

19. Oceanfront Inn II

Oceanfront Inn II
2.0 star property
4 km from Main Street Fort Pierce
7.8 out of 10, Good, (75 reviews)
"Had a excellent stay"
United States
Dennis
The price is AED 388
AED 616 total
includes taxes & fees
1 Oct - 2 Oct
Oceanfront Inn II
Pool

20. Motel 6 Ft. Pierce, FL, Fort Pierce

Motel 6 Ft. Pierce, FL, Fort Pierce
2.0 star property
7.3 km from Main Street Fort Pierce
5.6 out of 10, (1,007 reviews)
"The rooms are always clean and my favorite part is the fact this place is pet friendly to all."
United States
Caitlin
The price is AED 202
AED 234 total
includes taxes & fees
25 Sep - 26 Sep
Motel 6 Ft. Pierce, FL, Fort Pierce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Main Street Fort Pierce

Find the best Main Street Fort Pierce areas and neighborhoods for the activities you enjoy most.
A coastal area with a narrow waterway, a beach, and residential buildings.

Lakewood Park

While Lakewood Park isn't home to many top sights, Lakewood Park Regional Park / Pool and McKee Botanical Garden are some notable places to visit nearby.

Spanish Lakes Country Club Village

While there might not be top attractions in Spanish Lakes Country Club Village, you can explore the larger area and discover places like Lakewood Park Regional Park / Pool and Harbor Branch Ocean Discovery Center.

A calm lake reflecting trees and a clear sky.

Spanish Lakes Fairways

While Spanish Lakes Fairways might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Lakewood Park Regional Park / Pool and Endless Summer Vineyard & Winery.

A coastal city with a bay, mangrove islands, and a clear blue sky.

Meadowood

If you're looking for some top things to see and do in Meadowood and surrounding area, you can visit Lakewood Park Regional Park / Pool and Endless Summer Vineyard & Winery.

A mosaic sign with 'Mainstreet Fort Pierce' written on it.

Panther Woods

If you're looking for some top things to see and do in Panther Woods and surrounding area, you can visit Lakewood Park Regional Park / Pool and Endless Summer Vineyard & Winery.

Top Main Street Fort Pierce Hotel Reviews

Vero Beach Inn & Suites I-95

Vero Beach Inn & Suites I-95

10/10 Excellent
"Outstanding presentation"
WILLIE lee 1-night trip
Posted 1 hour ago
Vero Beach Inn & Suites I-95

Frequently asked questions

What is Main Street Fort Pierce like?
Main Street Fort Pierce is a neighborhood that travelers like for its waterfront, art, and shopping. Be sure to check out Sunrise Theater and Fort Pierce City Marina as part of your Main Street Fort Pierce travel plans.
How many hotels can I expect to find in Main Street Fort Pierce?
Book one of Expedia's 7 hotels and other accommodations in Main Street Fort Pierce and start exploring everything Fort Pierce has to offer.
If I need to cancel my hotel reservation in Main Street Fort Pierce, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to review the top deals on offer in Main Street Fort Pierce.
Where can I learn more about changing or cancelling my trip to Main Street Fort Pierce?
For additional details about changing or cancelling your trip to Main Street Fort Pierce, head over to our customer service page.
What is there to do in this Fort Pierce neighborhood?
Sights like Sunrise Theater and Official Highwaymen Art Gallery can be part of your cultural tour of Main Street Fort Pierce. Fort Pierce City Marina and Fort Pierce Farmer's Market are also a couple of places to visit in the neighborhood. A few places to visit in the area around Main Street Fort Pierce include Manatee Education and Observation Center, House of Seven Gables, and A.E. Backus Museum. Marina at Fort Pierce and Causeway Cove are also worth a visit when you're out sightseeing in Fort Pierce.