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Compare 5,892 hotels close to Main Street with room rates, reviews, and availability. Most hotels are fully refundable.

Anchor In Distinctive Waterfront Lodging

3.0 star property
9.4 out of 10, Exceptional, (1000)
"This is a quaint, smaller hotel, overlooking the wharf of Hyannis "
The price is AED 1,484
AED 1,888 total
includes taxes & fees
17 Aug - 18 Aug
Anchor In Distinctive Waterfront Lodging

Cape Cod Motor Inn

10.0 out of 10, Exceptional, (6)
"A great place to stay in Cape Cod. "
The price is AED 621
AED 710 total
includes taxes & fees
4 Aug - 5 Aug
Cape Cod Motor Inn

Uncommoner Hotel by Reverie Boutique Collection

3.0 star property
9.4 out of 10, Exceptional, (13)
"The property was so cute!! Such a fun little place that’s close to everything"
The price is AED 713
AED 845 total
includes taxes & fees
1 Sep - 2 Sep
Uncommoner Hotel by Reverie Boutique Collection

Freebird Motor Lodge by Reverie Boutique Collection

3.5 star property
9.6 out of 10, Exceptional, (223)
"Great place !!"
The price is AED 656
AED 777 total
includes taxes & fees
1 Sep - 2 Sep
Freebird Motor Lodge by Reverie Boutique Collection

SeaCoast Inn

2.0 star property
9.0 out of 10, Wonderful, (662)
"Spacious room, convenient location, nice to have kitchenette. "
The price is AED 500
AED 573 total
includes taxes & fees
1 Sep - 2 Sep
SeaCoast Inn

Margaritaville Resort Cape Cod

4.0 star property
8.8 out of 10, Excellent, (241)
"Great location, spacious rooms, good size pools and a lazy river. It is a restful oasis to retreat to, once you have explored the towns of the cape, including Hyannis, Chatham and Falmouth Great fun and friendly staff. "
The price is AED 673
AED 980 total
includes taxes & fees
24 Aug - 25 Aug
Margaritaville Resort Cape Cod

Cape Cod Inn

2.0 star property
8.8 out of 10, Excellent, (454)
"Always love coming here. Right in the heart of Hyannis for dining, shopping "
The price is AED 375
AED 429 total
includes taxes & fees
1 Sep - 2 Sep
Cape Cod Inn

The Club at New Seabury

3.5 star property
9.0 out of 10, Wonderful, (325)
"Great stay! Didn't notice it being dated or dirty at all like some reviews said. We loved it!"
The Club at New Seabury

Courtyard By Marriott Cape Cod Hyannis

3.0 star property
8.8 out of 10, Excellent, (469)
"Great stay! "
The price is AED 804
AED 920 total
includes taxes & fees
24 Aug - 25 Aug
Courtyard By Marriott Cape Cod Hyannis

Hyannis Inn

2.0 star property
8.6 out of 10, Excellent, (1005)
"It was perfect for what we needed a place to stay before catching the ferry the next day. We would definitely stay again. "
Hyannis Inn

Hampton Inn & Suites Cape Cod-West Yarmouth

2.5 star property
8.8 out of 10, Excellent, (1000)
"Our stay was great1 rooms were clean and the staff very accomodating. Close to restaurants and beaches."
The price is AED 624
AED 715 total
includes taxes & fees
1 Sep - 2 Sep
Hampton Inn & Suites Cape Cod-West Yarmouth

Bayside Resort Hotel

3.0 star property
8.8 out of 10, Excellent, (1443)
"great stay"
Bayside Resort Hotel

The Escape Inn

2.5 star property
9.4 out of 10, Exceptional, (597)
"Love the escape inn...very clean, very quiet love it every time I'm there!!!"
The price is AED 656
AED 751 total
includes taxes & fees
3 Aug - 4 Aug
The Escape Inn

Doubletree by Hilton Cape Cod - Hyannis

4.0 star property
8.4 out of 10, Very Good, (844)
"Everything was very good."
The price is AED 777
AED 890 total
includes taxes & fees
1 Sep - 2 Sep
Doubletree by Hilton Cape Cod - Hyannis

Holiday Inn Hyannis by IHG

3.0 star property
8.2 out of 10, Very Good, (906)
"Property was nice, had a room with a jetted tub that was amazing! "
The price is AED 452
AED 517 total
includes taxes & fees
1 Sep - 2 Sep
Holiday Inn Hyannis by IHG

Cape Sands Inn

2.5 star property
8.4 out of 10, Very Good, (1004)
"Great stay."
The price is AED 325
AED 372 total
includes taxes & fees
1 Sep - 2 Sep
Cape Sands Inn

Beach Breeze Inn

3.0 star property
9.8 out of 10, Exceptional, (201)
"Fabulous inn! Would highly recommend!"
The price is AED 996
AED 1,170 total
includes taxes & fees
1 Sep - 2 Sep
Beach Breeze Inn

Frederick William House

3.5 star property
9.6 out of 10, Exceptional, (278)
"Wonderful stay! Close to access Main Street and other things we wanted to do. "
The price is AED 813
AED 931 total
includes taxes & fees
26 Aug - 27 Aug
Frederick William House

Parker Beach Lodge

3.0 star property
8.6 out of 10, Excellent, (303)
"It was a nice place to stay in"
The price is AED 691
AED 791 total
includes taxes & fees
1 Sep - 2 Sep
Parker Beach Lodge

Cape Cod Family Resort and Parks

2.5 star property
8.2 out of 10, Very Good, (544)
"It is best for kids active. Family trip."
The price is AED 1,200
AED 1,373 total
includes taxes & fees
27 Aug - 28 Aug
Cape Cod Family Resort and Parks
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Main Street Hotel Reviews

Hotels near Other Attractions

Frequently asked questions

What's the area like around Main Street?

If you're planning to come to the area to visit Main Street, take some time to see the rest of the sights while you're in town. If you're looking for a convenient place to stay, check out the 29 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Main Street?

Cape Cod Irish Village is one of the top choices for your stay based on our traveler data, and this resort offers a golf course and 2 restaurants. It's located 4.8 mi (7.7 km) from Main Street. Other good options within a few miles include Craigville Beach Inn and The Ocean View.

How many hotels will I find near Main Street?

Expedia has 29 hotels and other accommodations within a mile from Main Street.

If I need to cancel the hotel reservation for my stay near Main Street, will I receive a refund?

Yes! Most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the top deals on offer near Main Street.

Where can I learn more about changing or cancelling my trip in the area near Main Street?

To access more information about picking new dates or cancelling your stay near Main Street, head over to our customer service page.

What can I see and do near Main Street?

Study the collections at Centerville Historical Museum, Cahoon Museum of American Art, or Toad Hall Classic Sports Car Museum. You can check out the local talent at Cape Cod Melody Tent, Cotuit Center for the Arts, and Barnstable Performing Arts Center. Dip your toes in the water at Craigville Beach, Keyes Beach, and Dowses Beach.