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Compare 491 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Hathor Concordia

3.0 star property
Concordia
8.6 out of 10, Excellent, (353)
"Very clean room at affordable price. The dinning is of excellent quality at very reasonable price. The staff are quite friendly and helpful."
United States
Amir
Hathor Concordia

COSTA NORTE HOSTERIA

3.0 star property
Colón
The price is AED 194
AED 194 total
3 Dec - 4 Dec
COSTA NORTE HOSTERIA

Mayim Hotel Termal & SPA

3.0 star property
Concordia
8.8 out of 10, Excellent, (5)
"Muy lindo hotel , lástima q se rompió el aire acondicionado y no hay secador de pelo an la habitación "
United States
Catalina
The price is AED 339
AED 339 total
8 Dec - 9 Dec
Mayim Hotel Termal & SPA

O2 Hotel Gualeguaychú

2.5 star property
Gualeguaychú
7.8 out of 10, Good, (65)
"Hotel is very comfortable and clean. There is no breakfast or hotel parking, and the wifi does not work properly in most floors and rooms. Other than that, the staff is very friendly and nice. "
United States
Esteban
The price is AED 129
AED 129 total
22 Dec - 23 Dec
O2 Hotel Gualeguaychú

Intersur Colon

3.0 star property
Colón
10.0 out of 10, Exceptional, (2)
"Letti molto comodi, belle piscine, personale gentile, pulizia buona, colazione buona. Ottimo rapporto qualità prezzo. "
Italy
Francesco
The price is AED 327
AED 327 total
4 Dec - 5 Dec
Intersur Colon

El Tránsito Hotel Boutique

3.5 star property
Concepción
10.0 out of 10, Exceptional, (3)
"This is an excellent Hotel and experience. The staff is vibrant and attentive. I would rate this hotel as one of the best, if not the best hotel I have ever stayed at. "
United States
Jerrie
The price is AED 2,189
AED 2,189 total
30 Dec - 31 Dec
El Tránsito Hotel Boutique

Marriott Corrientes Hotel

4.5 star property
Corrientes
10.0 out of 10, Exceptional, (3)
"Very nice hotel"
United States
Jeffrey
The price is AED 434
AED 434 total
19 Dec - 20 Dec
Marriott Corrientes Hotel

Casa del Árbol

3.0 star property
Concepción del Uruguay
8.4 out of 10, Very Good, (8)
"La primera vez que venga a Concepcion del Uruguay, quiero alquilar en" la casa del arbol" Me sentí muy bienvenida y en buena compañía, los anfitriones son maravillosos "
Mexico
Olga Beatriz
The price is AED 142
AED 142 total
3 Dec - 4 Dec
Casa del Árbol

Club Valle Termal Resort

3.0 star property
Federacion
9.2 out of 10, Wonderful, (94)
"Lamentablemente el lugar no refleja lo contratado por la plataforma. Cuando llegamos no tenían nuestras reservas, nos enviaron a una habitación con puerta de vidrio que no cerraba, arañas en la habitación, las sábanas viejas y manchadas, colchones vencidos y sin forro. Una experiencia espeluznante. "
Costa Rica
Pablo
The price is AED 160
AED 160 total
19 Dec - 20 Dec
Club Valle Termal Resort

Hotel y Spa Termas del Este

3.0 star property
Federacion
8.4 out of 10, Very Good, (12)
"good for a 1 night stay"
Canada
Chase
Hotel y Spa Termas del Este

Totoras Apart Federacion

2.5 star property
Federacion
7.2 out of 10, Good, (25)
"Buena estadia para unos dias .todo muy limpio a pesar de que estan aun terminando dptos.tal vez deben cuidar más los horarios de descanso del turista con los ruidos de la obra . Pocos utensilios de cocina si se quiere cocinar ahi mismo.Pero tranquilo y suficiente"
Argentina
Silvia
Totoras Apart Federacion

La Casona de Susana

3.0 star property
Colon
7.4 out of 10, Good, (25)
"La propietaria respeta el precio acordado. En verano si usás más de 8 horas por día el aire acondicionado te cobran un plus."
Argentina
Marlene Ruth
The price is AED 176
AED 176 total
3 Dec - 4 Dec
La Casona de Susana

Posada Che Teindy

2.5 star property
Colonia Carlos Pellegrini
The price is AED 386
AED 386 total
3 Dec - 4 Dec
Posada Che Teindy

Hotel Crespo

3.0 star property
Crespo
10.0 out of 10, Exceptional, (1)
Hotel Crespo

Don Pedro Apart Hotel

2.0 star property
Federacion
10.0 out of 10, Exceptional, (1)
"Estuvo muy bien, la atención fue muy buena. "
Costa Rica
Marianela
The price is AED 111
AED 111 total
2 Jan - 3 January 2026
Don Pedro Apart Hotel

Urban Hotel

3.0 star property
Federacion
2.0 out of 10, (1)
"Ambiente deixa a desejar, muito sujo, café da manhã ruim, sem opção. Baratas no ambiente."
Brazil
FABIO
Urban Hotel

Costarenas Hotel & Spa

3.5 star property
Colon
8.6 out of 10, Excellent, (58)
"spectacular since we arrived the tstaff was wonderful and kind to us very helpful and nice answering all our questions, the hotel very comfortable!! the river view stunning"
Argentina
Lisette
The price is AED 430
AED 430 total
6 Dec - 7 Dec
Costarenas Hotel & Spa

Hotel Rio

3.0 star property
Chajarí
8.8 out of 10, Excellent, (11)
"Lindo hotel, moderno, limpio, buena atencion, sumaria opciones saladas en el desayuno, como huevos revueltos."
Argentina
SANTIAGO
The price is AED 285
AED 285 total
3 Dec - 4 Dec
Hotel Rio

Donsuites Apart Hotel

3.0 star property
Corrientes
8.6 out of 10, Excellent, (105)
"Loved this place, super clean, and the staff were very nice and helpful😍"
United States
Nora
The price is AED 275
AED 275 total
3 Dec - 4 Dec
Donsuites Apart Hotel

Bungalows Mexico

2.5 star property
Concepción del Uruguay
8.8 out of 10, Excellent, (12)
"Local estava limpo, a cama é ótima, mas o banheiro a água n esquentava. O atendimento foi bom, são atenciosos. "
Brazil
Eduardo
The price is AED 175
AED 175 total
9 Dec - 10 Dec
Bungalows Mexico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Stay near popular Mesopotamia attractions

Learn more about Mesopotamia

Experience the romantic area of Mesopotamia—waterfalls, bird watching, and sights from Termas de Chajarí to Termas de Federacion.

Mesopotamia showing a river or creek and forest scenes

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Find out more about Mesopotamia

Top reasons to visit Mesopotamia

  • Outdoor Adventures: Mesopotamia offers thrilling activities like hiking and birdwatching, perfect for nature lovers.
  • Stunning National Parks: Explore breathtaking landscapes and diverse wildlife in the region's beautiful national parks.
  • Romantic Atmosphere: The enchanting scenery and relaxing vibes make it an ideal spot for couples and tranquil getaways.
  • Picnic Areas: Enjoy scenic picnic spots that enhance the outdoor experience with picturesque views.
  • Variety of Accommodations: Choose from top-rated hotels and family-friendly options to ensure a memorable stay.

Find great hotels near Mesopotamia

Explore a variety of hotel options in Mesopotamia, Argentina, perfect for families seeking an unforgettable vacation experience. With a selection of top-rated accommodations, you'll find everything from comfortable rooms to exceptional amenities. Discover competitive room rates, insightful hotel reviews, and the best hotels to make your stay enjoyable and memorable. Embrace the charm of Mesopotamia while enjoying the ideal lodging tailored to your needs.

  • El Tránsito Hotel Boutique: Experience a delightful family getaway at El Tránsito Hotel Boutique, a charming 3.5-star hotel located 29.0km from Mesopotamia. This family-friendly property is designed with children in mind, offering complimentary cribs, an engaging arcade game room, and a dedicated children's pool. Guests appreciate the warm atmosphere, making it an ideal choice for those traveling with kids. With its inviting ambiance and thoughtful amenities, El Tránsito ensures a memorable stay for families seeking adventure and relaxation.

Where to stay near Mesopotamia

Mesopotamia, Argentina, offers a unique blend of romantic and relaxing vibes, making it an ideal destination for outdoor enthusiasts and adventure seekers. Explore the stunning scenery, picnic areas, and beautiful properties while soaking in breathtaking city views. Popular destinations in and around Mesopotamia promise memorable experiences, ensuring that every traveler finds something special in this enchanting region.

  • Mercedes: Located 49.9km from Mesopotamia, Mercedes is a vibrant city that offers a blend of outdoor adventures and scenic beauty. The city sees a steady flow of visitors throughout the year, with peak seasons in July and from December to January. Travelers flock to Mercedes for its beautiful golf courses and exciting water park, making it an ideal destination for families and adventure seekers alike. Nearby attractions include a national state park, where nature lovers can explore picturesque trails, and a theme park that promises fun for all ages.
  • Concepción: Situated 35.4km away from Mesopotamia, Concepción is a charming city that attracts visitors seeking outdoor adventures and stunning landscapes. The city enjoys steady tourist traffic, peaking in April, July, and September. Concepción offers access to national and natural parks, perfect for hiking, birdwatching, or simply enjoying the serene environment. With its diverse outdoor activities, it provides a refreshing escape for those looking to connect with nature and indulge in scenic experiences.
  • Uguay: A quaint village located 27.4km from Mesopotamia, Uguay is a hidden gem that experiences seasonal tourism. Peak visitor months are January, March, and November, drawing those in search of tranquility and natural beauty. Surrounded by lush natural parks, Uguay is perfect for those who enjoy peaceful walks and wildlife observation. This charming village offers a slower pace, making it an ideal retreat for travelers looking to unwind and immerse themselves in the serene landscapes of Mesopotamia.

Things to do in Mesopotamia

In Mesopotamia, Argentina, visitors can enjoy a variety of outdoor activities such as birdwatching, hiking, and exploring local wildlife. The region's natural beauty makes it an ideal spot for those who appreciate outdoor seating while soaking in the picturesque surroundings. Whether you're an avid nature lover or simply seeking a relaxing getaway, Mesopotamia offers a unique blend of adventure and tranquility for every traveler.

Shopping

In Mesopotamia, Argentina, visit the bustling Shopping Sur, where you’ll find a mix of local and international brands. For a more traditional experience, browse the Mercado de Posadas, a vibrant market filled with unique handicrafts and souvenirs that reflect the region's rich culture.

Recreation

In Mesopotamia, indulge in rejuvenating treatments at the serene Termas de Río Hondo, known for its thermal springs and wellness therapies. Explore the lush landscapes while enjoying yoga sessions at eco-friendly retreats, or unwind with meditation classes that connect you to nature's tranquility.

Adventure

Explore the stunning Ibera Wetlands, a paradise for wildlife enthusiasts, offering boat tours to spot caimans, capybaras, and diverse bird species. For thrill-seekers, visit the Misiones jungle for zip-lining and hiking through lush trails, immersing yourself in breathtaking landscapes and rich biodiversity.

Nightlife

In Mesopotamia, Argentina, experience vibrant nightlife at El Club de la Música, where live bands ignite the atmosphere. Nearby, La Casa del Jazz offers smooth tunes and a cozy vibe, perfect for relaxing with friends while enjoying local drinks and delicious bites.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Mesopotamia

To save money on your trip to Mesopotamia, Argentina, consider visiting during the off-peak months when prices are lower, avoiding July, August, and December. Book your hotel about a month in advance for the best rates, and look for last-minute deals on platforms like Expedia. Tuesday is the cheapest day to stay, while Monday is the most expensive. Utilize Expedia's filters to find eco-friendly accommodations and consider package deals that combine flights, hotels, and activities for extra savings. Don't forget to explore free local attractions for a budget-friendly experience.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Mesopotamia are , where the prices are slightly lower. This is in comparison to July to August and December, where prices are slightly higher.
  • The best time to book a hotel: Booking a hotel around Mesopotamia about 1 month out from when you are planning to stay is usually when prices are lowest. If you're a little more spontaneous, you could also peruse Expedia's last minute deals for hotels, look out for the green banner below the price, as this indicates a cheaper deal.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Mesopotamia is Tuesday. The most expensive day to stay around Mesopotamia is Monday.
  • Find cheap hotels on Expedia: Expedia’s search tool makes it easy for you to choose your budget, preferred location, and other preferences. You can organize your results to display prices from lowest to highest, ensuring you find the most affordable hotels first. Additionally, you can narrow down your choices by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and eco-friendly hotels available for booking.
  • Consider bundling your trip: You can save money by combining your hotel stay in Mesopotamia with your flights and activities through an Expedia package deal.

Find the best attractions near Mesopotamia

In Mesopotamia, Argentina, travelers can immerse themselves in the beauty of national parks, making it a prime destination for those seeking outdoor adventures and stunning scenery. Popular activities include hiking through lush landscapes and enjoying the thrilling experience of nature. Whether you're looking for a peaceful retreat or an adrenaline-fueled excursion, Mesopotamia offers a wealth of attractions that cater to all types of adventurers.

  • Portal Carambola: Located 22.5km from Mesopotamia, this national park offers stunning scenery and adventure opportunities, perfect for outdoor enthusiasts seeking a blend of nature and excitement in a tranquil setting.

Best time to go to Mesopotamia

The best time to visit Mesopotamia depends on your weather preferences. The hottest average temperature around Mesopotamia is in January and February. February is mostly sunny. The coolest average temperature around Mesopotamia is in May and July. July is mostly sunny.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January80.1°F (26.700000000000003°C)Light RainSunnyModerately HighAverage
February77.7°F (25.4°C)Light RainMostly Sunny
March72.9°F (22.700000000000003°C)Light RainMostly SunnyModerately HighAverage
April66.7°F (19.3°C)Light RainMostly SunnyAverageAverage
May59.5°F (15.3°C)Light RainMostly Sunny
June60.1°F (15.6°C)Light RainMostly Sunny
July53.4°F (11.9°C)Light RainMostly SunnyAverageSlightly High
August63.7°F (17.6°C)Light RainMostly SunnyAverageSlightly High
September60.6°F (15.9°C)Light RainMostly SunnyAverageAverage
October65.8°F (18.8°C)Light RainMostly SunnyAverageAverage
November72.3°F (22.4°C)Light RainSunnyModerately HighAverage
December77.0°F (25.0°C)Light RainSunnyAverageSlightly High

The nearest major airports for your trip to Mesopotamia

When planning your trip to Mesopotamia, Argentina, you can fly into three major airports. Posadas (PSS-Libertador General Jose de San Martin) is 222.1km away, with nearby hotels like La Mision Posadas Hotel, Continental Posadas Hotel, and Bagu Grand Crucero Posadas, all offering airport transportation services. Resistencia (RES-Resistencia Intl.) is 181.9km from Mesopotamia, featuring options such as Amérian Hotel Casino Gala and Gala Hotel y Convenciones. Corrientes (CNQ-Corrientes Intl.) is the closest at 164.2km, with hotels like Turismo Hotel Casino and La Alondra Casa De Huéspedes providing shuttle and transportation services. Each airport offers convenient access to local accommodations for a comfortable stay.

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