Midtown Vacations

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Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most. Learn more about Midtown
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

2 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Find hotels in Downtown St. Louis

Midtown Hotel Deals

Residence Inn by Marriott St Louis Downtown
Residence Inn by Marriott St Louis Downtown
3 out of 5
525 S Jefferson Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AED 466 per night from May 25 to May 26
AED 466
AED 555 total
includes taxes & fees
25 May - 26 May
7.8/10 Good! (1,001 reviews)
"The room smelled and looked clean and fresh. The property is kind of in down-town Saint Louis, but it was fenced in so felt fairly safe. The breakfast was excellent. Overall a great stay."

Reviewed on 29 April 2025

Residence Inn by Marriott St Louis Downtown
Element St. Louis Midtown
Element St. Louis Midtown
3 out of 5
3763 Forest Park Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AED 514 per night from May 22 to May 23
AED 514
AED 601 total
includes taxes & fees
22 May - 23 May
9/10 Wonderful! (487 reviews)
Great hotel, good value for money.
"Amazing hotel. Very clean and friendly staff. Amazing breakfast in the morning. Couple of things: The bathroom lacked bodywash (the bodywash bottle was empty) and there was no hand wash soap. Adding a self parking will enhance customer experience."

Reviewed on 29 April 2025

Element St. Louis Midtown
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
3 out of 5
2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AED 441 per night from May 18 to May 19
AED 441
AED 515 total
includes taxes & fees
18 May - 19 May
9.4/10 Exceptional! (2,489 reviews)
"The people were helpful and friendly. Lots of interesting places walkable."

Reviewed on 3 May 2025

Drury Plaza Hotel St. Louis at the Arch
See all 1,766 properties in Midtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Midtown

St. Louis University

St. Louis University

4.5/5(292 reviews)

Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its acclaimed theater scene.

St. Louis University
The Joplin Homestead

Scott Joplin House State Historic Site

Learn about the local history of St. Louis when you spend time at Scott Joplin House State Historic Site. Experience the area's acclaimed theater scene or attend a baseball game.

Scott Joplin House State Historic Site
Busch Stadium

Busch Stadium

4.5/5(1,469 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

Busch Stadium