Vacation Homes in Monroe County

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Our top choices for Monroe County vacation homes

Charming 2-bedroom house at Mark Twain Lake

Charming 2-bedroom house at Mark Twain Lake
Stoutsville
10.0 out of 10, Exceptional, (31 reviews)
"This cabin was great!! Great location for getting to the lake to fish. Cabin was clean and comfortable; perfect for our trip. Will definitely stay here again. Thanks Dea!!"
United States
Matt H.
Charming 2-bedroom house at Mark Twain Lake

Tastefully restored historic home in quaint town, 20 minute drive to Columbia MO

Tastefully restored historic home in quaint town, 20 minute drive to Columbia MO
Centralia
10.0 out of 10, Exceptional, (160 reviews)
"Always wonderful staying at the Rollins House Inn! "
United States
Syndy D.
Tastefully restored historic home in quaint town, 20 minute drive to Columbia MO

3 Bedroom 2 Bath Cabin nestled in the woods minutes from Mark Twain Lake.

3 Bedroom 2 Bath Cabin nestled in the woods minutes from Mark Twain Lake.
Stoutsville
10.0 out of 10, Exceptional, (87 reviews)
"Our stay was great! "
United States
Heather W.
3 Bedroom 2 Bath Cabin nestled in the woods minutes from Mark Twain Lake.

Holder House at Beautiful Mark Twain Lake.

Holder House at Beautiful Mark Twain Lake.
Stoutsville
9.8 out of 10, Exceptional, (59 reviews)
"We have stayed here for several years, and it was great, as usual. "
United States
Leslie C.
Holder House at Beautiful Mark Twain Lake.

Mark Twain lake getaway at Blue Lagoon!

Mark Twain lake getaway at Blue Lagoon!
Monroe City
10.0 out of 10, Exceptional, (37 reviews)
"We had a great stay, perfect space for a family gathering!"
United States
Stacy (.
Mark Twain lake getaway at Blue Lagoon!

“Peaceful Retreat” @ MTL

“Peaceful Retreat” @ MTL
Monroe City
10.0 out of 10, Exceptional, (106 reviews)
"Beautiful property with gracious hosts. As close to Indian creek marina as you can be. "
United States
Kevin S.
“Peaceful Retreat” @ MTL

Beautiful historic home in downtown Centralia, just 20 minutes from Columbia, MO

Beautiful historic home in downtown Centralia, just 20 minutes from Columbia, MO
Centralia
10.0 out of 10, Exceptional, (47 reviews)
"Great place to stay. "
United States
braden l.
Beautiful historic home in downtown Centralia, just 20 minutes from Columbia, MO

Mallard Cottage - At the Lodges of Long Branch

Mallard Cottage - At the Lodges of Long Branch
Bevier Township
10.0 out of 10, Exceptional, (1 review)
"Great location if you’re interested in fishing Long Branch Lake! We had the best extended weekend crappie fishing."
United States
Hannah C.
The price is AED 606
AED 1,001 total
includes taxes & fees
22 Jun - 23 Jun
Mallard Cottage - At the Lodges of Long Branch

Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness

Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness
Cairo
10.0 out of 10, Exceptional, (28 reviews)
"We really enjoyed how this felt like a home away from home. The Christmas decorations, the ambiance, and all the extra effort put in to make our stay wonderful made this a trip to remember. Thank you so much for letting us stay at your beautiful lake house, we’ll be back for sure!"
United States
Sean W.
Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness

Family-Friendly Home. Sleeps 14. Just minutes away from Mark Twain Lake.

Family-Friendly Home. Sleeps 14. Just minutes away from Mark Twain Lake.
Perry
10.0 out of 10, Exceptional, (13 reviews)
"The house was very clean and perfect for our stay!"
United States
Kristal R.
Family-Friendly Home. Sleeps 14. Just minutes away from Mark Twain Lake.

Blue Heron Hut - At the Lodges of Long Branch

Blue Heron Hut - At the Lodges of Long Branch
Bevier Township
10.0 out of 10, Exceptional, (1 review)
"We enjoyed our stay. It was nice and clean and had everything that we needed. The host was very friendly and responsive "
United States
Ryan S.
Blue Heron Hut - At the Lodges of Long Branch

Unwind on Vine

Unwind on Vine
Macon
9.6 out of 10, Exceptional, (27 reviews)
"Very happy with the accommodations. "
United States
keith r.
The price is AED 512
AED 631 total
includes taxes & fees
11 Jun - 12 Jun
Unwind on Vine

Newly Built Shouse Near Mark Twain Lake!

Newly Built Shouse Near Mark Twain Lake!
Monroe City
10.0 out of 10, Exceptional, (9 reviews)
"What a great place! It rained half the time we were there, yet there was plenty of room to hang out inside, play cornhole and watch movies. We loved our overnight stay and look forward to returning. "
United States
Christina H.
The price is AED 808
AED 1,147 total
includes taxes & fees
7 Jun - 8 Jun
Newly Built Shouse Near Mark Twain Lake!

'Grace Place' Clark House on Farm: Shared Hot Tub!

'Grace Place' Clark House on Farm: Shared Hot Tub!
Clark
10.0 out of 10, Exceptional, (32 reviews)
"We had such a relaxing time and really enjoyed conversations w/ our host and loving on her animals."
United States
Derek L.
'Grace Place' Clark House on Farm: Shared Hot Tub!

Cozy 3 bed, 2 bath home close to historic downtown Hannibal

Cozy 3 bed, 2 bath home close to historic downtown Hannibal
Hannibal
10.0 out of 10, Exceptional, (56 reviews)
"Clean, updated, comfortable beds, good location."
United States
Anonymous traveler
Cozy 3 bed, 2 bath home close to historic downtown Hannibal

The Benjamin House, Quality and Comfortable Townhouse with small town feel

The Benjamin House, Quality and Comfortable Townhouse with small town feel
Hallsville
10.0 out of 10, Exceptional, (5 reviews)
"Nice clean place"
United States
Bryon C.
The Benjamin House, Quality and Comfortable Townhouse with small town feel

Spacious Home w/ Pond ~ 13 Mi to Columbia!

Spacious Home w/ Pond ~ 13 Mi to Columbia!
Hallsville
7.6 out of 10, Good, (13 reviews)
"Great place for a staff of baseball coaches to stay at. AC had issues first night we were there and they jumped on it quick to get it back up and running"
United States
Will D.
Spacious Home w/ Pond ~ 13 Mi to Columbia!

Totally Renovated Home on 5 Acres - Just 4 Miles From Mark Twain Lake

Totally Renovated Home on 5 Acres - Just 4 Miles From Mark Twain Lake
Monroe City
10.0 out of 10, Exceptional, (8 reviews)
"We enjoyed our stay and had a fabulous time. The house was super clean and everything that you need for a great stay. We really enjoyed spending time by the fire pit outside, the scenery was beautiful and relaxing and the wood stacked and ready was a special treat. "
United States
Carroll S.
Totally Renovated Home on 5 Acres - Just 4 Miles From Mark Twain Lake

Spacious 4-bedroom 3 bath house in fabulous Hallsville

Spacious 4-bedroom 3 bath house in fabulous Hallsville
Hallsville
8.0 out of 10, Very Good, (1 review)
"Nice home to stay in!"
United States
Jessica D.
Spacious 4-bedroom 3 bath house in fabulous Hallsville

2 bedroom house near Mark Twain Lake on Salt River! WiFi and Boat parking!

2 bedroom house near Mark Twain Lake on Salt River! WiFi and Boat parking!
Santa Fe
10.0 out of 10, Exceptional, (1 review)
"The deck was just beautiful. The common area was spacious and comfortable. Kitchen had everything we needed. Bathroom was good size and the hot shower was perfect. The place was so clean and area was very quiet. I would suggest to not use google maps because it took us the wrong way but we found our way. The host was responsive and accommodating . We will definitely be back. "
United States
Dawn S.
2 bedroom house near Mark Twain Lake on Salt River! WiFi and Boat parking!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Monroe County Hotel Reviews